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SUBCHRONIC: 作品数：36被引量：51H指数：4; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：王玉荣周安祥王子元林磊光王秀玲更多>>; 相关机构：白银公司劳动卫生研究所哈尔滨医科大学上海医科大学中国预防医学科学院更多>>; 相关期刊：《Journal of Rare Earths》《Chinese Journal of Integrative Medicine》《Science China Chemistry》《现代出版》更多>>; 相关基金：国家自然科学基金中国博士后科学基金更多>>

Berberine Hydrochloride Improves Cognitive Function and Hippocampal Antioxidant Status in Subchronic and Chronic Lead Poisoning: 《Chinese Journal of Integrative Medicine》2025年第1期49-54,共6页Fatemeh Zare Mehrjerdi Azadeh Shahrokhi Raeini Fatemeh Sadate Zebhi Zeynab Hafizi Reyhaneh Mirjalili Faezeh Afkhami Aghda; Supported by the Research Project of Shahid Sadoughi University of Medical Sciences and Health Services(No.5894)Yazd Neuroendocrine Research Center;School of Medicine,Shahid Sadoughi University of Medical Sciences and Health Services,Yazd(8915133149),Iran。; Objective: To determine the neuroprotective effects of berberine hydrochloride(BBR) against lead-induced injuries on the hippocampus of rats. Methods: Wistar rats were exposed orally to doses of 100 and 500 ppm lead a...; 关键词：lead acetate BERBERINE HIPPOCAMPUS oxidative stress Morris water maze

Intestinal microbiota dysbiosis contributes to the liver damage in subchronic arsenic-exposed mice: 《Acta Biochimica et Biophysica Sinica》2024年第12期1774-1788,共15页Ling Dong Peng Luo Aihua Zhang; supported by the grant from the National Natural Science Foundation of China(No.81430077).; There is an extensive amount of evidence that links changes in the intestinal microbiota structure to the progression and pathophysiology of many liver diseases.However,comprehensive analysis of gut flora dysbiosis in...; 关键词：ARSENIC intestinal microbiota fecal microbiota transplantation intestinal barrier liver damage

The risk factors and threshold level of subchronic inhalation exposure of reclaimed water: 《Journal of Environmental Sciences》2024年第3期639-650,共12页Jiayang Kong Yun Lu Yunru Ren Menghao Chen Gang Liu Liangliang Shi; supported by the National Natural Science Foundation of China (Nos.51738005 and 21777084)。; Inhalation of reclaimed water is known to cause lung infammation,and free endotoxins have been shown to be a major risk factor for acute exposure.Subchronic exposure has also been shown to induce infammatory responses...; 关键词：Reclaimed water Inhalation exposure Risk factor THRESHOLD Infammation ENDOTOXIN

Subchronic Oral Toxicity Evaluation of Sodium Dehydroacetate: A 90-day Repeated Dose Study in Rats被引量：1: 《Biomedical and Environmental Sciences》2022年第4期296-311,共16页FANG Jin LIU Hai Bo ZHI Yuan FENG Yong Quan WANG Hui Ling CUI Wen Ming ZHANG Ji Yue WANG Hua Li YU Zhou JIA Xu Dong; supported by the National Key R&D Program of China[2019YFC1605203];China Food Safety Talent Competency Development Initiative:CFSA 523 Program; Objective The present study was undertaken to evaluate the subchronic oral toxicity of sodium dehydroacetate(DHA-Na)and to determine the point of departure(POD),which is a critical factor in the establishment of an ac...; 关键词：Sodium dehydroacetate Sub-chronic toxicity 90-day repeated oral dose test Benchmark dose Point of departure

Tolerance and safety evaluation of sodium sulfate:A subchronic study in laying hens: 《Animal Nutrition》2021年第2期576-586,共11页Bing Liu Jiaming Zhu Qin Zhou Dongyou Yu; the National Key Research and Development Program of China(grant no.2013BAD20B02);Feed Quality and Safety Supervision Project of Ministry of Agriculture,Beijing,China.; Sodium sulfate(Na2SO4)is a readily available chlorine-free source of sodium,which could be used to reduce sodium chloride to maintain the ratio between chlorine and sodium in poultry diets.Dietary supplementation with...; 关键词：Sodium sulfate TOLERANCE HISTOPATHOLOGY Intestinal function Laying hen

Subchronic Oral Cadmium Exposure Exerts both Stimulatory and Suppressive Effects on Pulmonary Inflammation/Immune Reactivity in Rats被引量：4: 《Biomedical and Environmental Sciences》2019年第7期508-519,共12页KULAS Jelena NINKOV Marina TUCOVIC Dina POPOV Aleksandrov Aleksandra UKROPINA Mirela CAKIC MILOSEVIC Maja MUTIC Jelena KATARANOVSKI Milena MIKROV Ivana; supported by the Ministry of Education,Science and Technological Development of the Republic of Serbia(Grant#173039); Objective The aim of this study is to investigate the effects of oral cadmium(Cd) ingestion on the pulmonary immune response. Methods Determination of Cd content in lungs and histopathological evaluation of the tissue...; 关键词：RATS ORAL cadmium administration Lungs CYTOKINE response

Hepcidin-orchestrated Hemogram and Iron Homeostatic Patterns in Two Models of Subchronic Hepatic injury被引量：1: 《Biomedical and Environmental Sciences》2019年第3期153-161,共9页Ibtsam GHEITH Abubakr EL-MAHMOUDY; Objective This study was designed to evaluate hematological disorders and the orchestrating roles of hepcidin and IL-6 in rat models of thioacetamide(TAA) and carbon tetrachloride(CCl_4) hepatotoxicity. Methods Rats w...; 关键词：ANEMIA IRON Liver Fibrosis HEPCIDIN IL-6

Subchronic Oral Toxicity Evaluation of Lanthanum： A 90-day, Repeated Dose Study in Rats被引量：10: 《Biomedical and Environmental Sciences》2018年第5期363-375,共13页FANG Hai Qin YU Zhou ZHI Yuan FANG Jin LIChen Xi WANG Yi Mei PENG Shuang Qing JIA Xu Dongl; supported by China Food Safety Talent Competency Development Initiative:CFSA 523 Program;the National Natural Science Foundation of China[No.81402683]; Objective The present study was undertaken to evaluate the subchronic toxicity of lanthanum and to determine the no observed adverse effect level（NOAEL）,which is a critical factor in the establishment of an acceptab...; 关键词：LANTHANUM Subchronic toxicity 90-day repeated oral dose test No observed adverse effectLevel Acceptable dietary intake Benchmark dose

Subchronic Oral Toxicity of Silica Nanoparticles and Silica Microparticles in Rats被引量：1: 《Biomedical and Environmental Sciences》2018年第3期197-207,共11页LIANG Chun Lai XIANG Qian CUI Wen Ming FANG Jin SUN Na Na ZHANG Xiao Peng LI Yong Ning YANG Hui YU Zhou JIA Xu Dong; supported by China Food Safety Talent Competency Development Initiative:CFSA 523 Program; Objective To investigate the subchronic oral toxicity of silica nanoparticles（NPs） and silica microparticles（MPs） in rats and to compare the difference in toxicity between two particle sizes.Methods Sprague-Dawley...; 关键词：Subchronic toxicity Silica nanoparticles Silica microparticles RATS

Effects of subchronic oral toxic metal exposure on the intestinal microbiota of mice被引量：13: 《Science Bulletin》2017年第12期831-840,共10页Qixiao Zhai Tianqi Li Leilei Yu Yue Xiao Saisai Feng Jiangping Wu Jianxin Zhao Hao Zhang Wei Chen; supported by the National Natural Science Foundation of China Key Program(31530056);National Natural Science Foundation of China(31601452);the General Financial Grant from the China Postdoctoral Science Foundation(2016M590412);the Natural Science Foundation of Jiangsu Province(BK20160175);the General Financial Grant from the Jiangsu Postdoctoral Science Foundation(1601113C);BBSRC Newton Fund Joint Centre Award; Oral exposure to toxic metals such as cadmium （Cd）, lead （Pb）, copper （Cu） and aluminum （AI） can induce various adverse health effects in humans and animals. However, the effects of these metals on the gut mic...; 关键词：CadmiumLeadAluminumCopperGut microbiotaMetal

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