DIAZOXIDE

作品数:19被引量:33H指数:4
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相关领域:医药卫生更多>>
相关作者:宋治远仝识非钟理胡红玲赵建平更多>>
相关机构:第三军医大学西南医院华中科技大学第三军医大学附属西南医院重庆医科大学更多>>
相关期刊:《中国心脏起搏与心电生理杂志》《Acta Pharmacologica Sinica》《World Journal of Gastroenterology》《介入放射学杂志》更多>>
相关基金:国家自然科学基金国家教育部博士点基金国家科技支撑计划更多>>
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Diazoxide toxicity in congenital hyperinsulinism:A case report
《World Journal of Clinical Pediatrics》2024年第4期102-108,共7页Roberta Pajno Camilla Visconti Carmen Bucolo Maria Pia Guarneri Paolo Del Barba Paolo Silvani Marco Gregnanin Graziano Barera 
BACKGROUND Diazoxide is the sole approved drug for congenital hyperinsulinism;however,diuretic administration and vigilant monitoring are crucial to prevent and promptly identify potentially life-threatening adverse e...
关键词:DIAZOXIDE HYPOGLYCEMIA Congenital hyperinsulinism Side effect Case report 
Efficacy and safety of octreotide treatment for diazoxide-unresponsive congenital hyperinsulinism in China被引量:1
《Pediatric Investigation》2020年第1期29-36,共8页Bingyan Cao Di Wu Chang Su Jiajia Chen Xuejun Liang Min Liu Wenjing Li Xiaoqiao Li Chunxiu Gong 
The study was funded by National Key Research and Development Program of China(2016YFC1305304);Beijing Children's Hospital Young Investigator Program(No.BCHYIPA-2016-06);Beijing Municipal Administration of Hospital Clinical Medicine Development of Special Funding Support(No.ZYLX201821).
Importance: Octreotide is an off-label medicine for congenital hyperinsulinism (CHI), but is currently widely used for treatment of patients with CHI. Thus far, variable efficacy and adverse effects have been reported...
关键词:OCTREOTIDE Congenital hyperinsulinism EFFICACY Safety 
Beneficial effects of adenosine triphosphate-sensitive K^+ channel opener on liver ischemia/reperfusion injury被引量:3
《World Journal of Gastroenterology》2014年第41期15319-15326,共8页Mateus Antunes Nogueira Ana Maria Mendona Coelho Sandra Nassa Sampietre Rosely Antunes Patzina Fabiano Pinheiro da Silva Luiz Augusto Carneiro D'Albuquerque Marcel Cerqueira Cesar Machado 
Supported by Fundao de Amparoà Pesquisa do Estado de So Paulo,No.2010/19078-1
AIM: To investigate the effect of diazoxide administration on liver ischemia/reperfusion injury.
关键词:Liver ischemia/reperfusion DIAZOXIDE K+ channel opener Mitochondrial ATP-sensitive potassium channel Liver mitochondria 
Effect of indomethacin on electrical field stimulation-induced contractions of isolated transverse and longitudinal rat gastric fundus strips被引量:2
《World Journal of Gastroenterology》2005年第34期5358-5361,共4页Salimeh Afshin Mansoor Keshavarz Mahmood Salami Fatemeh Mirershadi Bijan Djahanguiri 
AIM: To study the effects of indomethacin on the isolated transverse and longitudinal rat gastric fundus strips.METHODS: The strips were suspended in an organ bath containing oxygenated Krebs solution, and contractile...
关键词:Gastric fundus KATP channel INDOMETHACIN DIAZOXIDE Glybenclamide 
Cardioprotective effects of mitochondrial K_(ATP) channels activated at different time被引量:5
《Chinese Medical Journal》2004年第5期647-651,共5页魏珂 闵苏 龙村 
Backgroud Recent studies in adult hearts have indicated that K ATP channels in the inner mitochondrial membrance are responsible for the protection. And we investigated whether opening of mitochondrial K ATP ...
关键词:immature heart  · mitochondria  · diazoxide  · ATP-dependent potassium channel  · CARDIOPROTECTION 
Diazoxide对乳鼠窦房结细胞模拟缺血-再灌注时的保护作用研究
《中国心脏起搏与心电生理杂志》2004年第z1期79-80,共2页仝识非 宋治远 钟理 
  目的为探讨KATP通道开放剂Diazoxide对模拟缺血-再灌注时培养乳鼠窦房结细胞的保护作用及其可能机制.……
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