SPHINGOSINE

作品数：80被引量：236H指数：8
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相关领域：医药卫生更多>>
相关作者：张翼肖琼尹大力徐美林王菁更多>>
相关机构：北京协和医学院首都医科大学天津市胸科医院天津医科大学更多>>
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相关基金：国家自然科学基金广东省自然科学基金北京市自然科学基金国家重点基础研究发展计划更多>>
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Sphingosine-1-Phosphate Protects Against the Development of Cardiac Remodeling via Sphingosine Kinase 2 and the S1PR2/ERK Pathway
《Current Medical Science》2022年第4期702-710,共9页Hui YAN Hu ZHAO Shao-wei YI Hang ZHUANG Dao-wen WANG Jian-gang JIANG Gui-fen SHEN 
supported by the National Natural Science Foundation of China(No.81873505).
Objective:Cardiac remodeling is a common pathological change in various cardiovascular diseases and can ultimately result in heart failure.Thus,there is an urgent need for more effective strategies to aid in cardiac p...
关键词：sphingosine-l-phosphate cardiac remodeling sphingosine kinase 2 sphingosine-1-phosphate receptor extracellular regulated protein kinase 
Sphingolipids in cardiovascular and cerebrovascular systems:Pathological implications and potential therapeutic targets
《World Journal of Cardiology》2013年第4期75-86,共12页Masahito Kawabori Rachid Kacimi Joel S Karliner Midori A Yenari 
Supported by Grants from the National Institutes of Health (NS40516,to Yenari MA);the Veteran's Merit Award(Yenari MA);the Uehara Foundation(2013 Research Fellowship,to Kawabori M);the National Heart,Lung,and Blood Institute/NHLBI(1P01 HL 68738 and R01 HL 090606 to Karliner JS);Grants to Yenari MA and Karliner JS were administered by the Northern California Institute for Research and Education;supported by resources of the Veterans Affairs Medical Center, San Francisco,California
The sphingolipid metabolites ceramide,sphingosine,and sphingosine-1-phosphate(S1P) and its enzyme sphingosine kinase(SphK) play an important role in the regulation of cell proliferation,survival,inflammation,and cell ...
关键词：SPHINGOLIPIDS Sphingosine-1-phosphate SPHINGOSINE KINASE CERAMIDE KINASE 
Sphingosine signaling and atherogenesis被引量：5
《Acta Pharmacologica Sinica》2004年第7期849-854,共6页Cang-baoXU JacobHANSEN-SCHWARTZ LarsEDVINSSON 
This work is supported by Swedish Research Council (grandNo5958).
Sphingosine-1-phosphate (S1P) has diverse biological functions acting insidecells as a second messenger to regulate cell proliferation and survival, and extracellularly, as aligand for a group of G protein-coupled rec...
关键词：sphingosine 1-phosphate sphingosine kinase sphingosine-1-phosphatereceptors ENDOTHELIUM MYOCARDIUM smooth muscle ARTERIOSCLEROSIS 
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