GUANOSINE

作品数:53被引量:106H指数:6
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相关领域:医药卫生更多>>
相关作者:余奕李晓东杨文修赵玉英梁鸿更多>>
相关机构:北京大学南开大学中国药科大学香港科技大学更多>>
相关期刊:《International Journal of Ophthalmology(English edition)》《Chinese Medical Journal》《Signal Transduction and Targeted Therapy》《Neural Regeneration Research》更多>>
相关基金:国家自然科学基金国家重点基础研究发展计划上海市自然科学基金更多>>
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  • 期刊=Neural Regeneration Researchx
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Guanosine-5'-triphosphate cyclohydrolase 1 regulated long noncoding RNAs are potential targets for microglial activation in neuropathic pain被引量:4
《Neural Regeneration Research》2021年第3期596-600,共5页Yan-Hu Liang Guo-Wu Chen Xue-Song Li Shu Jia Chun-Yang Meng 
supported by the National Natural Science Foundation of China,Nos.81572205 and 81974345(both to CYM)。
Several studies have confirmed that microglia are involved in neuropathic pain.Inhibition of guanosine-5′-triphosphate cyclohydrolase 1(GTPCH1)can reduce the inflammation of microglia.However,the precise mechanism by...
关键词:cells factors INFLAMMATION MICROGLIA PAIN pathway protein RNA 
Current perspectives on the antidepressant-like effects of guanosine被引量:1
《Neural Regeneration Research》2016年第9期1411-1413,共3页Luis E.B.Bettio Joana Gil-Mohapel Ana Lucia S.Rodrigues 
funding from Conselho Nacional de Desenvolvimento Científico e Tecnológico(CNPq;#403120/2012-8,#308723/2013-9,#449436/2014-4);Coordenacao de Aperfeicoamento de Pessoal de Nível Superior(CAPES),Brazil
Purines have a recognized importance as intercellular mes- sengers. These molecules play an important role in the de- velopment and maintenance of the central nervous system (CNS), as well as in its response to path...
关键词:Current perspectives on the antidepressant-like effects of guanosine 
Puerarin prevents high glucose-induced apoptosis of Schwann cells by inhibiting oxidative stress被引量:10
《Neural Regeneration Research》2012年第33期2583-2591,共9页Yingying Wu Bing Xue Xiaojin Li Hongchen Liu 
supported by the National Natural Science Foundation of China, No. 30973354
Oxidative stress may be the unifying factor for the injury caused by hyperglycemia in diabetic peripheral neuropathy. Puerarin is the major isoflavonoid derived from Radix puerariae and has been shown to be effective ...
关键词:PUERARIN diabetic peripheral neuropathy hyperglycemia Schwann cell apoptosis caspase mitochondrial transmembrane potential oxidative stress 8-hydroxy-2-deoxyguanosine reactive oxygen radical 
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