supported by the National Natural Science Foundation of China (22222509, 52025035, 52103194, and 22105199);The Ministry of Science and Technology of China (2022YFE0110200);Bureau of International Cooperation Chinese Academy of Sciences (121522KYSB20200029);Jilin Province Science and Technology Development Plan (YDZJ202101ZYTS131, 20220402037GH, and 20210508049RQ);Jilin Provincial International Cooperation Key Laboratory of Biomedical Polymers (20210504001GH);The Youth Innovation Promotion Association of Chinese Academy of Sciences (2020232)。
Neoantigen cancer vaccines have been envisioned as one of the most promising means for cancer therapies.However,identifying neoantigens for tumor types with low tumor mutation burdens continues to limit the effectiven...