supported by the National Key Research and Development Program of China(No.2021YFA1301100,2021YFA1301101);Shandong Provincial Natural Science Foundation of China(No.SYS202202);the Research Project of Jinan Microecological Biomedicine Shandong Laboratory(China)(No.JNL-2023009Q,JNL-2022012B).
In the mammalian heart,cardiomyocytes undergo a transient window of proliferation that leads to regenerative impairment,limiting cardiomyocyte proliferation and myocardial repair capacity.Cardiac developmental pattern...
BACKGROUND Non-ST segment elevation myocardial infarction(NSTEMI)poses significant challenges in clinical management due to its diverse outcomes.Understanding the prognostic role of hematological parameters and derive...
Objectives This study aimed to develop a hospital-community-family trinity cardiac rehabilitation(CR)intervention program and assess its’effects on patients with acute myocardial infarction(AMI)after percutaneous cor...
Supported by the National Natural Science Foundation of China(No.82174215);the National Science Fund for Excellent Young Scholars(No.82222075);the National Major Scientific and Technological Special Project for"Significant New Drugs Development"(No.2019ZX09201004-001-011)。
Objective:To assess the cardioprotective effect and impact of Qishen Granules(QSG)on different ischemic areas of the myocardium in heart failure(HF)rats by evaluating its metabolic pattern,substrate utilization,and me...
supported by the National Natural Science Foundation of China(No.82173772,82003916,82204586,81773677);Shaanxi Provincial Key Research and Development Program(No.2022ZDLSF05-06);the Open Project Program of MOE Key Laboratory of Drug Quality Control and Pharmacovigilance(No.DQCP20/21PQ07);the innovation Capability Support Program of Shaanxi(No.2020TD-041)。
Objective:Myocardial inflammation during myocardial infarction(MI)could be inhibited by regulating arachidonic acid(AA)metabolism.Recent studies demonstrated that Sini Decoction(SND)was identified to be an effective p...
funded by the Ministry of Science and Higher Education of the Republic of Kazakhstan,grant numbers AP14969403 and AP23485820.
Myocardial infarction(MI)is one of the leading causes of death globally among cardiovascular diseases,necessitating modern and accurate diagnostics for cardiac patient conditions.Among the available functional diagnos...
BACKGROUND Primary percutaneous coronary intervention(PCI)is the preferred treatment for ST-segment elevation myocardial infarction(STEMI).However,in patients with high thrombus burden,immediate stenting during PCI ca...
BACKGROUND The incidence of acute myocardial infarction(AMI)is rising,with cardiac rupture accounting for approximately 2%of deaths in patients with acute ST-segment elevation myocardial infarction(STEMI).Ventricular ...
supported by the R&D project of Pazhou Lab(Huangpu)under Grant 2023K0610;the National Natural Science Foundation of China(Grants 12126602);the National Natural Science Foundation of China(Grants 82030102);the Shenzhen Medical Research Fund(Grants C2302001);the Shenzhen Science and Technology Innovation Committee(No.ZDSYS20200810171403013);the Chinese Postdoctoral Science Foundation(No.2022M721463);the Ministry of Science and Technology of China(Grants 2022YFC3702703).
Objective This study aimed to investigate the impact of glycemic control and diabetes duration on subsequent myocardial infarction(MI)in patients with both coronary heart disease(CHD)and type 2 diabetes(T2D).Methods W...
funded by the National Key Research and Development Projects of China(2022YFA1104500,2022YFC3602400);National Nature Science Foundation of China(91939303,92249301,U22A6008);Youth Independent Innovation Project of Chinese People's Liberation Army General Hospital(22QNFC043).
Objective:To explore the approach of minimally invasive transthoracic intramyocardial cellular transplantation under echocardiographic guidance to promote ischemic myocardial repair in a preclinical big-animal study.M...