supported by a grant from the key project of the National Natural Science Foundation of China (to Qinghua ZHOU) (No. 30430300);National Natural Science Foundation of China (to Qinghua ZHOU) (No. 30670922);INTERNATION Scienc and Techniquie COOPRATION PROGRAM OF CHINA (ISCP) (to Qinghua ZHOU)(No.2006DFB32330)
Background and objective Lung cancer has not only become the most frequent malignant cancer which is increasing fastest among all the tumors, but also become the rst killer