National Natural Science Foundation of China:Study on the Mechanism of Tuina Inhibiting the Spinal Cord Central Sensitization of Neuropathic Pain through Regulates Interleukin-10/β-Endorphin Pathway in Spinal Microglia(No.82205302);Study on the Mechanism of Peripheral and Central Pain in Lumbar disc herniation with Nerve Injury and the Analgesia Mechanism of Tuina(No.82030121);Shanghai Sailing Program:Study on the Analgesic Mechanism of Tuina Inhibiting Spinal Cord Central Sensitization based on Microglia and Related Pro-inflammatory Factors(20YF1450900);Science Foundation of Yueyang Hospital of Integrated Traditional Chinese and Western Medicine:Study on the Mechanism of Tuina Analgesia based on Spinal Cord Microglia and Inflammatory Factors(2021yygq03)。
OBJECTIVE:To observe the analgesic effects of Tuina on neuropathic pain(NPP)and the underlying mechanisms.METHODS:Forty-eight Sprague-Dawley(SD)rats were assigned by random into three treatment groups:sham,chronic con...
Natural Science Foundation-funded Project:Study on the Mechanism of Tuina and Tuina in Regulating the Synaptic Plasticity of Spinal Dorsal Horn in Lumbar Disc Herniation Based on LncRNA-HOTAIR/miR-219 Mediated NMDAR Pathway(No.82174523);Natural Science Foundation of Fujian Province:Study on the Mechanism of Tuina Regulating the Synaptic Plasticity of Spinal Dorsal Horn in Lumbar Disc Herniation based on NMDAR-CAMK2-CREB Pathway(No.2020J01757);Study on Analgesic Mechanism of Tuina on Neuropathic Pain in Spinal Dorsal Horn/ACC Brain Region based on PKA-NMDA-NR2B Pathway(No.2020J01758);Fujian Health Science and Technology Program:Study on the Analgesic Mechanism of Tuina Manipulation On Lumbar Disc Herniation from the Efficacy of miR-219/NR2B Mediated Synaptic Transmission(No.2020GGA070);Effects of Tuina Point Press on AMPA/NMDA Receptor Scaffold Protein and Synaptic Plasticity in Spinal Dorsal Horn of Rats with Neuropathic Pain(No.2020CXA052)。
OBJECTIVE:To investigate whether the Chinese massage system,Tuina,exerts analgesic effects in a rat model of chronic constriction injury(CCI)by remodeling the synaptic structure in the spinal cord dorsal horn(SCDH).ME...
BACKGROUND Herpes zoster is caused by reactivation of latent varicella-zoster virus infection within the sensory nerve ganglion of the spinal or cranial nerves.Laryngeal herpes zoster is rare and involves superior lar...
To the best of our knowledge, this is the first report in the literature showing the efficacy of transcranial direct current stimulation (tDCS) in treating refractory post-herpetic neuralgia in a patient with dermatom...
BACKGROUND Neuralgia is frequently noted in patients with Kummell’s disease,and its mechanism is complex,rendering it challenging to treat.Percutaneous kyphoplasty(PKP)has been widely used to treat osteoporotic verte...
Objective: to summarize 21 cases of herpes zoster neuralgia patients nursing experience. Methods: select our hospital from February 2021 to January 2022,21 cases of herpes herpetic neuralgia patients with health educa...
Objective: to select patients with diabetes mellitus complicated with herpes zoster, treat them with modified Liuwei Dihuang Decoction combined with plum blossom needle and cupping, and observe their clinical curative...
Objective:To observe the efficacy of needling the Xi-Cleft points of yang meridians plus topical surrounding needling and pregabalin in treating postherpetic neuralgia(PHN)affecting the head and face and its influence...
Objective: to enhance the therapeutic effect of trigeminal neuralgia and analyze the therapeutic effect of acupuncture combined with carbamazepine. Methods: all the subjects were selected in our hospital. A total of 6...