supported by the NationalNature Science Foundation of China(82002056,32000969,92268206);The general funding grants(2020 M673672);the special funding grants(in-station,2022 T150789);the China Postdoctoral Science Foundation,theMilitaryMedical Research Projects(145AKJ260015000X,2022-JCJQ-ZD-096-00);National key research and development program(2022YFA1104604);Key Support Program for Growth Factor Research(SZYZ-TR-03);the Science Fund for National Defense Distinguished Young Scholars(2022-JCJQ-ZQ-016);Youth Independent Innovation Science Fund Project of PLA General Hospital(22QNFC018).
Background:Eccrine sweat gland(SG)plays a crucial role in thermoregulation but exhibits very limited regenerative potential.Although SG lineage-restricted niches dominate SG morphogenesis and benefit SG regeneration,r...