OLIGONUCLEOTIDE

作品数：101被引量：206H指数：7
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相关机构：北京大学首都医科大学南京医科大学中国科学院更多>>
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Design and application of 60mer oligonucleotide microarray in SARS coronavirus detection被引量：4
《Chinese Science Bulletin》2003年第12期1165-1169,共4页SHI Rong MA Wenli WU Qinghua ZHANG Bao SONG Yanbin GUO Qiuye XIAO Weiwei WANG Yan ZHENG Wenling 
The 60mer oligonucleotide microarray was designed and applied to detecting of SARS (severe acute res-piratory syndrome) coronavirus. Thirty 60mer specific oligos were designed to cover the whole genome of the first su...
关键词：SARS CORONAVIRUS OLIGONUCLEOTIDE MICROARRAY RD tech-nique fluorescent LABELING molecular hybridization. 
DNA microarray synthesis by using PDMS molecular stamps (Ⅲ)——Optimization for the reaction conditions被引量：5
《Chinese Science Bulletin》2002年第13期1073-1076,共4页XIAO Pengfeng, LU Zuhong, LIU Zhengchun, HE Quanguo & HE NongyueKey Laboratory for Molecular and Biomolecular Electronics of Ministry of Education, Southeast University, Nanjing 210096, China 
This work was supported by the 863 National High Technology Research ; Development Program (Grant Nos. 103-13-05-01 and 101-01-01);the 973 National Key Fundamental Research Project (Grant No. G1998051204);the National Science Foundation of China (Gra
Optimization for the technological processes of fabricating oligonucleotide microarray by the molecular stamping method is studied in this note. Three factors that affect the pressing coupling reactions of the nucleos...
关键词：OLIGONUCLEOTIDE MICROARRAY MOLECULAR STAMPING method DNA chemical synthesis. 
Spectroscopic investigation on the telomeric DNA base sequence repeat
《Chinese Science Bulletin》2002年第2期108-111,共4页Sichuan Xu Xicheng Ai Zhaoyong Sun Qiyuan Zhang Xingkang Zhang 
Thiswork was supported by the Science Creative Project of the Chinese Academy of Sciences (Grant No. KJCX2-H2).
Telomeres are protein-DNA complexes at the terminals of linear chromosomes, which protect chromoso-mal integrity and maintain cellular replicative capacity. From single-cell organisms to advanced animals and plants, s...
关键词：DNA TELOMERE OLIGONUCLEOTIDE FLUORESCENCE quantum yield. 
MULTIPLE MUTATIONS ON DOUBLE-STRANDED DNA
《Chinese Science Bulletin》1990年第20期1729-1733,共5页朱榴琴 申同健 
Project supported by the National High Technology Foundation (Term No. 103-20).
The site-specific mutagenesis of the gene has become an important technique in gene modification and protein engineering. Among all methods, the primer extension one using single-stranded DNA (such as the infective fo...
关键词：DOUBLE-STRANDED DNA MULTIPLE MUTATION OLIGONUCLEOTIDE primer. 
CHARACTERIZATION OF β-THALASSEMIA MUTATIONS IN CHINESE USING OLIGONUCLEOTIDE HYBRIDIZATION WITH AMPLIFIED DNA
《Chinese Science Bulletin》1990年第3期261-262,共2页黄淑帧 周霞娣 朱皓 任兆瑞 曾溢滔 
β-Thalassemia is a relatively common monogenic disorder in China. Up to the present, over 60 different mutations have been found to cause β-thalassemia in the world; and each ethnic group or population carries its o...
关键词：alleles mutant populations migration ETHNIC pathogenesis DNA prevention carries GLOBIN 
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