PARKINSON_DISEASE

作品数:123被引量:198H指数:7
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相关作者:余舒扬陈滢陈晓春王涛张巧俊更多>>
相关机构:首都医科大学附属北京天坛医院福建医科大学环境与疾病相关基因教育部重点实验室西安交通大学更多>>
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相关基金:国家自然科学基金北京市自然科学基金国家重点基础研究发展计划陕西省自然科学基金更多>>
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  • 期刊=Neural Regeneration Researchx
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Health-related quality of life in Parkinson's disease patients in northeastern Sicily, Italy An ecological perspective被引量:1
《Neural Regeneration Research》2013年第17期1615-1622,共8页Letteria Spadaro Lilla Bonanno Giuseppe Di Lorenzo Placido Bramanti Silvia Marino 
supported by a grant from the Ministry of Health (Research for the Strategic Program 2007)
Parkinson's disease has a negative impact on health-related quality of life in Parkinson's disease patients. Depression, cognitive impairment, coping strategies, dyskinesia, gait disorders and complications of dopam...
关键词:neural regeneration neurodegenerative disease health-related quality of life Parkinson's disease ecological model Parkinson's Disease Questionnaire-39 Items social variables the UnifiedParkinson Disease Rating Scale motor subscales CAREGIVER grants-supported paper 
Establishing motor disorder mouse models of Parkinson disease Comparison of 6-hydroxydompamine and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine
《Neural Regeneration Research》2007年第10期611-616,共6页Zhi hua Ren Jie Gao Yan Chen Zhen yu Lu 
the grants from Shanghai Educational Committee, No. 03BZ03;Department of Education for Doctor Foundation, No. 20040266014;Shanghai Jiao Tong University Medical School for Doctor Foundation, No. BXJ0304
At present, pathogenesis and mechanism of Parkinson disease (PD) are still unclear. Animal models of PD are essential tools in studies on etiology and therapy and should mimic the chronic pathological process, histo...
关键词:Parkinson disease 6-HYDROXYDOPAMINE 1-methyl-4-phenyl-1  2  3  6-tetrahydropyridine motor behavioral dysfunction 
Intrastriatal glial cell line-derived neurotrophic factors for protecting dopaminergic neurons in the substantia nigra of mice with Parkinson disease被引量:4
《Neural Regeneration Research》2007年第4期207-210,共4页Chenghua Xiao Yanqiang Wang Hongmei Liu Hongjun Wang Junping Cao Dianshuai Gao 
the Natural Science Foundation of Jiangsu Department of Education, No. 02KJB310009
BACKGROUND: Substantia nigra is deep in position and limited in range, the glial cell line-derived neurotrophic factor (GDNF) injection directly into substantia nigra has relatively greater damages with higher diff...
关键词:glial cell line-derived neurotrophic factor (GDNF) dopaminergic neurons 1 -methy1-4-pheny1- 1 2 3 6-tetrahydropyridine (MPTP) 
Alpha-synuclein and Parkinson disease被引量:2
《Neural Regeneration Research》2007年第4期239-243,共5页Hui Liu Xiaozhong Wang 
OBJECTIVE: To review the recent progresses on the studies of α -synuclein in the pathogenesis of Parkinson disease (PD) and look into the perspective of α -synuclein as a new therapy target. DATA SOURCES: To sea...
关键词:Α-SYNUCLEIN Parkinson's disease Lewy's body 
Risk factors for Parkinson disease and the path analysis: One-to-one paired design
《Neural Regeneration Research》2007年第2期117-120,共4页Xianhua Tan 
BACKGROUND: Parkinson disease (PD) results from the reduce of neurotransmitter dopamine that transmits intracellular information in brain caused by some reasons, then leads to the dynamic disequilibrium with anothe...
关键词:Parkinson disease risk factors Logistic models 
Dopamine transporter distribution in patients with Parkinson disease of different stages detected using single-photon emission computed tomography brain imaging
《Neural Regeneration Research》2007年第1期18-21,共4页Jiwu Zhang Lijuan Zhu Jianqiang Du Bo Liu 
BACKGROUND: Literatures have reported that the density changes of dopamine transporter is negatively correlated with the severity degree and grading of disease condition of Parkinson disease (PD). However, the dist...
关键词:Parkinson disease DOPAMINE tomography  emission-computed  single-photon 
Analysis of brain-stem auditory evoked potential and visual evoked potential in patients with Parkinson disease
《Neural Regeneration Research》2006年第5期449-452,共4页Qiaorong Deng Jianzhong Deng Yanmin Zhao Xiaohai Yan Pin Chen 
BACKGROUND: With the development of neuroelectrophysiology, it had been identified that all kinds of evoked potentials might reflect the functional status of corresponding pathway. Evoked potentials recruited in the ...
Feasibility of establishing model of Parkinson disease by injecting 6-hydroxydopamine at different parts of the nigrostriatal pathway in the brain of rats
《Neural Regeneration Research》2006年第2期126-129,共4页Yuefei Shen Xuean Mo Guifang Long 
Foundation for the Returned Overseas Chinese Scholars of Guangxi Zhuang Autonomous Region, No. 0448017
BACKGROUND: Previous researches found that animal models with Parkinson disease (PD) could be established by injecting 6-hydroxydopamine (6-OHDA) into medial forebrain bundle (MFB), substantia nigra compacta (...
关键词:Feasibility of establishing model of Parkinson disease by injecting 6-hydroxydopamine at different parts of the nigrostriatal pathway in the brain of rats 
Expression of calbindin D28K in substantia nigra of model rats with Parkinson disease被引量:2
《Neural Regeneration Research》2006年第2期121-125,共5页Dianshuai Gao Hongmei Liu Yanxia Ding Hongjun Wang Yanqiang Wang 
Scientific and Technological Project of State Ministry of Education, No. 204055; the Natural Science Foundation of Educational Bureau of Jiangsu Province, No. 02KJB310009
BACKGROUND: Previous researches suggested that expression level of calbindin D28K mRNA decreased in substantia nigra (SN) of model rats with Parkinson disease (PD), and this might be related to the decrease of an...
关键词:FIGURE Expression of calbindin D28K in substantia nigra of model rats with Parkinson disease 
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