PARKINSON_DISEASE

作品数：125被引量：198H指数：7
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相关机构：首都医科大学附属北京天坛医院福建医科大学环境与疾病相关基因教育部重点实验室西安交通大学更多>>
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Emerging role of microglia in the developing dopaminergic system:Perturbation by early life stress
《Neural Regeneration Research》2026年第1期126-140,共15页Kaijie She Naijun Yuan Minyi Huang Wenjun Zhu Manshi Tang Qingyu Ma Jiaxu Chen 
supported by the National Natural Science Foundation of China,Nos.82304990(to NY),81973748(to JC),82174278(to JC);the National Key R&D Program of China,No.2023YFE0209500(to JC);China Postdoctoral Science Foundation,No.2023M732380(to NY);Guangzhou Key Laboratory of Formula-Pattern of Traditional Chinese Medicine,No.202102010014(to JC);Huang Zhendong Research Fund for Traditional Chinese Medicine of Jinan University,No.201911(to JC);National Innovation and Entrepreneurship Training Program for Undergraduates in China,No.202310559128(to NY and QM);Innovation and Entrepreneurship Training Program for Undergraduates at Jinan University,Nos.CX24380,CX24381(both to NY and QM)。
Early life stress correlates with a higher prevalence of neurological disorders,including autism,attention-deficit/hyperactivity disorder,schizophrenia,depression,and Parkinson's disease.These conditions,primarily inv...
关键词：Chinese herbal drugs dopamine early life stress epigenetics gut-brain axis hypothalamo–pituitary–adrenal axis innate immune memory MICROGLIA neuroinflammation Parkinson disease PHAGOCYTOSIS REWARD 
Clinical observation of acupuncture and Tuina combined with Ba Duan Jin in improving motor function in patients with Parkinson disease in the early and middle stages
《Journal of Acupuncture and Tuina Science》2025年第2期151-158,共8页ZENG Liang GU You HU Jiawei YANG Hualan DONG Xiaowei PAN Guoliang ZHOU Fei 
上海市浦东新区科技发展基金民生科研专项资金医疗卫生项目,No.PKJ2020-Y107;上海市浦东新区卫生系统优秀青年医学人才培养计划,No.PWRq2024-50;上海浦东新区中医药传承创新发展示范试点项目,No.YC-2023-0128,No.YC-2023-0129,No.YC-2023-0202,No.YC-2023-0607;上海市浦东新区卫生系统领先人才培养计划,No.PWRl2023-08;上海市“十四五”中医特色专科和中医急诊能力提升孵化项目,No.ZYTSZK2-1.
Objective:To observe the improving effect of acupuncture and Tuina(Chinese therapeutic massage)combined with Ba Duan Jin(Eight-brocade Exercise)on motor function in patients with Parkinson disease(PD)in the early and ...
关键词：Acupuncture Therapy TUINA MASSAGE Eight-brocade Exercise Gongfa Parkinson Disease Motor Activity 
Effects of acupuncture on SATB1/p21 signaling pathway and SASPs in MPTP-induced Parkinson disease model mice
《Journal of Acupuncture and Tuina Science》2025年第1期1-11,共11页LI Guona ZHAO Chen WANG Zhaoqin HUA Xuegui WU Luyi ZHANG Xiyin SHEN Lin CHEN Ziyi HU Wenqing CHEN Yiyi CHENG Ling QIAO Yu 
国家中医药管理局高水平中医药重点学科建设项目,No.zyyzdxk-2023068;国家自然科学基金项目,No.82205260;上海市浦东新区卫计委名中医培养计划,No.PWRzm2020-12;浦东新区卫计委学科建设中医针灸重点专科,No.PWZzk2022-25.
Objective:To observe the effects of acupuncture on the motor function of Parkinson disease(PD)model mice and to investigate the neuroprotective effects of acupuncture on PD from the perspective of cellular senescence....
关键词：Acupuncture Therapy Point Baihui(GV20) Point Yanglingquan(GB34) Parkinson Disease Signal Transduction Cell Aging Mice 
Multi-omics analysis reveals the neuroprotective effect of Atractylodis Rhizoma Alba extract against Parkinson's disease in mouse
《Journal of Traditional Chinese Medicine》2024年第6期1111-1117,共7页KANG Sohi LEE Soong-In MOON Byeong Cheol SONG Jun Ho KIM Sung-Ho MOON Changjong LEE Sueun KIM Chul KIM Joong Sun 
the Development of Sustainable Application for Standard Herbal Resource by the Korea Institute of Oriental Medicine (No. KSN2012320)。
OBJECTIVE: To assess Atractylodis Rhizoma Alba extract(ARE) neuroprotective function in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine(MPTP)-treated mice and related genes. METHODS: Examined m RNA-DNA methylation change...
关键词：Parkinson disease nerve degeneration 1-methyl-4-phenyl-1 2 3 6-TETRAHYDROPYRIDINE Atractylodis Rhizoma Alba Methyl-seq 
Investigating efficacy mechanism of electroacupuncture in treating Parkinson disease through TMT proteomics
《Journal of Acupuncture and Tuina Science》2024年第6期470-481,共12页ZHU Lu LI Guona WU Pin WU Luyi SHEN Lin QIAO Yu LI Jing LI Lingjie WANG Zhaoqin CHEN Yiyi MA Xiaopeng LI Kunshan WU Huangan 
上海市老龄化和妇儿健康研究专项,No.2020YJZX0134;国家自然科学基金青年科学基金项目,No.82205260;上海市科学技术委员会科研计划项目,No.18401970700;上海市卫生健康委员会科研课题,No.20204Y0271;国家中医药管理局高水平中医药重点学科(针灸学)建设项目,No.ZYYZDXK-2023068.
Objective:To explore the therapeutic mechanism of electroacupuncture(EA)in treating Parkinson disease(PD)using Tandem mass tag(TMT)quantitative proteomics technology.Methods:Forty-eight PD patients were randomly divid...
关键词：Acupuncture Therapy ELECTROACUPUNCTURE PROTEOMICS Tandem Mass Spectrometry Cyclic AMP Parkinson Disease 
Correlations of transcranial sonography of substantia nigra characteristics with MRI iron deposition on substantia nigra in patients with Parkinson disease
《中国医学影像技术》2024年第8期1160-1163,共4页ZOU Quan CHEN Fei MENG Wenyu ZHENG Hong 
Objective To explore the correlations of transcranial sonography of substantia nigra(SN-TCS)characteristics with MRI iron deposition on substantia nigra in patients with Parkinson disease(PD).Methods Data of SN-TCS an...
关键词：Parkinson disease substantia nigra IRON ULTRASONOGRAPHY magnetic resonance imaging 
Effectivenss of electroacupuncture for skeletal muscle pain in Parkinson's disease:a Clinical randomized controlled trial被引量：1
《Journal of Traditional Chinese Medicine》2024年第2期388-395,共8页WANG Shaosong SUN Jingqing FENG Qingyin LI Bin WANG Xin YUAN Fan CUI Yingxue 
the Project of National Famous Old Chinese Medicine Experts Inheritance Studio Construction:the National Project of Taking Inheriting Experience of Prestigious Chinese Physicians Wang Linpeng(No.ZY202275)。
OBJECTIVE:To explore the effect of electroacupuncture on skeletal muscle pain in Parkinson's disease(PD).METHODS:A single-center randomized controlled trial was conducted with sixty patients with Parkinson's disease w...
关键词：Parkinson disease MUSCLE SKELETAL PAIN ELECTROACUPUNCTURE muscle tention mood disorders randomized controlled trial 
Prognosis Factors of Urinary Quality of Life in Parkinson Disease
《Open Journal of Therapy and Rehabilitation》2024年第1期10-17,共8页Ngor Side Diagne Sakhi Othman Ababacar Mamadou Gueye Marie Jeanne Sakho Fatou Dialo Mboup Amélie Ndeye Makarame Sy Papa Ndiouga Lo Ba Seydina Ousmane Anna Modji Basse Maouly Fall Adjaratou Dieynaba Sow Moustapha Ndiaye Amadou Gallo Diop 
Introduction: Quality of life in Parkinson disease is not necessary linked to motor symptoms. It’s correlated of overactive bladders and prostatic symptoms. Prognosis factors of urinary quality of life are unknown. O...
关键词：URINARY Quality of Life Parkinson Disease DAKAR 
Relationship among Parkinson’s disease, constipation, microbes, and microbiological therapy被引量：1
《World Journal of Gastroenterology》2024年第3期225-237,共13页Xin-Yang Yuan Yu-Sen Chen Zhou Liu 
This comprehensive review elucidates the complex interplay between gut microbiota and constipation in Parkinson’s disease(PD),a prevalent non-motor symptom contributing significantly to patients’morbidity.A marked a...
关键词：Parkinson disease CONSTIPATION Gut microbiota PREBIOTICS PROBIOTICS Fecal microbiota transplantation 
Gene therapy for Parkinson’s Disease and Ethical Challenges: A Systematic Review
《Advances in Parkinson's Disease》2023年第2期9-28,共20页Théodora M. Zohoncon Joseph Sawadogo Abdou Azaque Zoure Abdoul Karim Ouattara Marie N. L. Ouedraogo Luc Zongo Paul Ouedraogo Florencia W. Djigma Christelle W. M. Nadembèga Raphael Kabore Djénéba Ouermi Dorcas Obiri-Yeboah Jacques Simpore 
Background: Parkinson’s disease (PD) is a complex, multifactorial neurodegenerative disorder with a pathophysiology deriving from the synergy of abnormal aggregation of neuroinflammation, synuclein and dysfunction of...
关键词：Neurodegenerative Diseases Parkinson Disease Molecular Mechanism Gene Therapy Gene Therapy Ethics 
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