PARKINSON_DISEASE

作品数:123被引量:198H指数:7
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相关作者:余舒扬陈滢陈晓春王涛张巧俊更多>>
相关机构:首都医科大学附属北京天坛医院福建医科大学环境与疾病相关基因教育部重点实验室西安交通大学更多>>
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相关基金:国家自然科学基金北京市自然科学基金国家重点基础研究发展计划陕西省自然科学基金更多>>
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Effects of acupuncture on SATB1/p21 signaling pathway and SASPs in MPTP-induced Parkinson disease model mice
《Journal of Acupuncture and Tuina Science》2025年第1期1-11,共11页LI Guona ZHAO Chen WANG Zhaoqin HUA Xuegui WU Luyi ZHANG Xiyin SHEN Lin CHEN Ziyi HU Wenqing CHEN Yiyi CHENG Ling QIAO Yu 
国家中医药管理局高水平中医药重点学科建设项目,No.zyyzdxk-2023068;国家自然科学基金项目,No.82205260;上海市浦东新区卫计委名中医培养计划,No.PWRzm2020-12;浦东新区卫计委学科建设中医针灸重点专科,No.PWZzk2022-25.
Objective:To observe the effects of acupuncture on the motor function of Parkinson disease(PD)model mice and to investigate the neuroprotective effects of acupuncture on PD from the perspective of cellular senescence....
关键词:Acupuncture Therapy Point Baihui(GV20) Point Yanglingquan(GB34) Parkinson Disease Signal Transduction Cell Aging Mice 
Multi-omics analysis reveals the neuroprotective effect of Atractylodis Rhizoma Alba extract against Parkinson's disease in mouse
《Journal of Traditional Chinese Medicine》2024年第6期1111-1117,共7页KANG Sohi LEE Soong-In MOON Byeong Cheol SONG Jun Ho KIM Sung-Ho MOON Changjong LEE Sueun KIM Chul KIM Joong Sun 
the Development of Sustainable Application for Standard Herbal Resource by the Korea Institute of Oriental Medicine (No. KSN2012320)。
OBJECTIVE: To assess Atractylodis Rhizoma Alba extract(ARE) neuroprotective function in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine(MPTP)-treated mice and related genes. METHODS: Examined m RNA-DNA methylation change...
关键词:Parkinson disease nerve degeneration 1-methyl-4-phenyl-1 2 3 6-TETRAHYDROPYRIDINE Atractylodis Rhizoma Alba Methyl-seq 
Investigating efficacy mechanism of electroacupuncture in treating Parkinson disease through TMT proteomics
《Journal of Acupuncture and Tuina Science》2024年第6期470-481,共12页ZHU Lu LI Guona WU Pin WU Luyi SHEN Lin QIAO Yu LI Jing LI Lingjie WANG Zhaoqin CHEN Yiyi MA Xiaopeng LI Kunshan WU Huangan 
上海市老龄化和妇儿健康研究专项,No.2020YJZX0134;国家自然科学基金青年科学基金项目,No.82205260;上海市科学技术委员会科研计划项目,No.18401970700;上海市卫生健康委员会科研课题,No.20204Y0271;国家中医药管理局高水平中医药重点学科(针灸学)建设项目,No.ZYYZDXK-2023068.
Objective:To explore the therapeutic mechanism of electroacupuncture(EA)in treating Parkinson disease(PD)using Tandem mass tag(TMT)quantitative proteomics technology.Methods:Forty-eight PD patients were randomly divid...
关键词:Acupuncture Therapy ELECTROACUPUNCTURE PROTEOMICS Tandem Mass Spectrometry Cyclic AMP Parkinson Disease 
Correlations of transcranial sonography of substantia nigra characteristics with MRI iron deposition on substantia nigra in patients with Parkinson disease
《中国医学影像技术》2024年第8期1160-1163,共4页ZOU Quan CHEN Fei MENG Wenyu ZHENG Hong 
Objective To explore the correlations of transcranial sonography of substantia nigra(SN-TCS)characteristics with MRI iron deposition on substantia nigra in patients with Parkinson disease(PD).Methods Data of SN-TCS an...
关键词:Parkinson disease substantia nigra IRON ULTRASONOGRAPHY magnetic resonance imaging 
Effectivenss of electroacupuncture for skeletal muscle pain in Parkinson's disease:a Clinical randomized controlled trial被引量:1
《Journal of Traditional Chinese Medicine》2024年第2期388-395,共8页WANG Shaosong SUN Jingqing FENG Qingyin LI Bin WANG Xin YUAN Fan CUI Yingxue 
the Project of National Famous Old Chinese Medicine Experts Inheritance Studio Construction:the National Project of Taking Inheriting Experience of Prestigious Chinese Physicians Wang Linpeng(No.ZY202275)。
OBJECTIVE:To explore the effect of electroacupuncture on skeletal muscle pain in Parkinson's disease(PD).METHODS:A single-center randomized controlled trial was conducted with sixty patients with Parkinson's disease w...
关键词:Parkinson disease MUSCLE SKELETAL PAIN ELECTROACUPUNCTURE muscle tention mood disorders randomized controlled trial 
Prognosis Factors of Urinary Quality of Life in Parkinson Disease
《Open Journal of Therapy and Rehabilitation》2024年第1期10-17,共8页Ngor Side Diagne Sakhi Othman Ababacar Mamadou Gueye Marie Jeanne Sakho Fatou Dialo Mboup Amélie Ndeye Makarame Sy Papa Ndiouga Lo Ba Seydina Ousmane Anna Modji Basse Maouly Fall Adjaratou Dieynaba Sow Moustapha Ndiaye Amadou Gallo Diop 
Introduction: Quality of life in Parkinson disease is not necessary linked to motor symptoms. It’s correlated of overactive bladders and prostatic symptoms. Prognosis factors of urinary quality of life are unknown. O...
关键词:URINARY Quality of Life Parkinson Disease DAKAR 
Relationship among Parkinson’s disease, constipation, microbes, and microbiological therapy被引量:1
《World Journal of Gastroenterology》2024年第3期225-237,共13页Xin-Yang Yuan Yu-Sen Chen Zhou Liu 
This comprehensive review elucidates the complex interplay between gut microbiota and constipation in Parkinson’s disease(PD),a prevalent non-motor symptom contributing significantly to patients’morbidity.A marked a...
关键词:Parkinson disease CONSTIPATION Gut microbiota PREBIOTICS PROBIOTICS Fecal microbiota transplantation 
Gene therapy for Parkinson’s Disease and Ethical Challenges: A Systematic Review
《Advances in Parkinson's Disease》2023年第2期9-28,共20页Théodora M. Zohoncon Joseph Sawadogo Abdou Azaque Zoure Abdoul Karim Ouattara Marie N. L. Ouedraogo Luc Zongo Paul Ouedraogo Florencia W. Djigma Christelle W. M. Nadembèga Raphael Kabore Djénéba Ouermi Dorcas Obiri-Yeboah Jacques Simpore 
Background: Parkinson’s disease (PD) is a complex, multifactorial neurodegenerative disorder with a pathophysiology deriving from the synergy of abnormal aggregation of neuroinflammation, synuclein and dysfunction of...
关键词:Neurodegenerative Diseases Parkinson Disease Molecular Mechanism Gene Therapy Gene Therapy Ethics 
Bifurcations for counterintuitive post-inhibitory rebound spike related to absence epilepsy and Parkinson disease
《Chinese Physics B》2023年第9期206-219,共14页王宪军 古华光 贾雁兵 陆博 周辉 
the National Natural Science Foundation of China(Grant Nos.12072236,11872276,and11802086);the Postdoctoral Research Project of Henan Province,China(Grant No.19030095);the Science and Technology Development Program of Henan Province,China(Grant No.212102210543)。
Seizures are caused by increased neuronal firing activity resulting from reduced inhibitory effect and enhancement of inhibitory modulation to suppress this activity is used as a therapeutic tool.However,recent experi...
关键词:bifurcation threshold post-inhibitory rebound spike brain disease 
Protective effect of Tongdu Tiaoshen acupuncture combined with Xiaoxuming decoction(小续命汤)on dopaminergic neurons in Parkinson’s disease model被引量:4
《Journal of Traditional Chinese Medicine》2023年第3期484-493,共10页WU Haiyang WANG Ying HAN Wei LI Huihui JI Haisheng LIU Xiuxiu 
Supported by National Natural Science Foundation of China:Study on the Mechanism of Regulating miR-124 by Tongdu Tiaoshen Acupuncture to Promote Neuroprotection in Cerebral Ischemia Reperfusion Injury(No.81973933);Natural Science Fund for Colleges and Universities in Anhui Province:Study on the Regulatory Mechanism of Tongdu Tiaoshen Acupuncture on Dopaminergic Neurons in Parkinson’s Disease Model Mice Based on Mitochondrial Autophagy(No.KJ2019A0475)。
OBJECTIVE:To explore the possible mechanism of Tongdu Tiaoshen acupuncture combined with Xiaoxuming decoction(小续命汤,XXMD)in the treatment of Parkinson’s disease(PD).METHODS:C57BL/6 mice were randomly divided into ...
关键词:Parkinson disease ACUPUNCTURE dopaminergic neurons Tongdu Tiaoshen Xiaoxuming decoction mitochondrial autophagy 
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