PARKINSON_DISEASE

作品数：123被引量：198H指数：7
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相关机构：首都医科大学附属北京天坛医院福建医科大学环境与疾病相关基因教育部重点实验室西安交通大学更多>>
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Olfactory swab sampling optimization for α-synuclein aggregate detection in patients with Parkinson’s disease被引量：2
《Translational Neurodegeneration》2022年第1期390-400,共11页Matilde Bongianni Mauro Catalan Daniela Perra Elena Fontana Francesco Janes Claudio Bertolotti Luca Sacchetto Stefano Capaldi Matteo Tagliapietra Paola Polverino Valentina Tommasini Giulia Bellavita Elham Ataie Kachoie Roberto Baruca Andrea Bernardini Mariarosaria Valente Michele Fiorini Erika Bronzato Stefano Tamburin Laura Bertolasi Lorenzo Brozzetti Maria Paola Cecchini Gianluigi Gigli Salvatore Monaco Paolo Manganotti Gianluigi Zanusso 
Fondazione Cariverona:“Development and validation of a novel molecular assay forα-synuclein in patients with Parkinson’s disease and otherα-synucleinopathies”#2018.0708 to GZ and Brain Research Verona Foundation to GZ.Dr.Elena Fontana is attending a doctoral fellowship supported by COPAN group.
Background: In patients with Parkinson’s disease (PD), real-time quaking-induced conversion (RT-QuIC) detection of pathological α-synuclein (α-syn) in olfactory mucosa (OM) is not as accurate as in other α-synucle...
关键词：Parkinson disease ALPHA-SYNUCLEIN Real-time quaking-induced conversion assay Olfactory mucosa Cerebrospinal fluid 
No association between Parkinson disease and autoantibodies against NMDA-type glutamate receptors被引量：1
《Translational Neurodegeneration》2019年第1期127-133,共7页Franziska Hopfner Stefanie HMüller Dagmar Steppat Joanna Miller Nele Schmidt Klaus-Peter Wandinger Frank Leypoldt Daniela Berg Andre Franke Wolfgang Lieb Lukas Tittmann Monika Balzer-Geldsetzer Simon Baudrexel Richard Dodel Ruediger Hilker-Roggendorf Elke Kalbe Jan Kassubek Thomas Klockgether Inga Liepelt-Scarfone Brit Mollenhauer Petra Neuser Kathrin Reetz Oliver Riedel Claudia Schulte Jörg BSchulz Annika Spottke Alexander Storch Claudia Trenkwalder Hans-Ulrich Wittchen Karsten Witt Ullrich Wüllner Günther Deuschl Gregor Kuhlenbäumer 
Intramural funding of the Dept.of Neurology,Kiel University.
Background:IgG-class autoantibodies to N-Methyl-D-Aspartate(NMDA)-type glutamate receptors define a novel entity of autoimmune encephalitis.Studies examining the prevalence of NMDA IgA/IgM antibodies in patients with ...
关键词：NMDA antibody NMDA IgA/IgM antibodies Parkinson disease Cognitive impairment 
Nicotine from cigarette smoking and diet and Parkinson disease:a review被引量：6
《Translational Neurodegeneration》2017年第1期174-180,共7页Chaoran Ma Yesong Liu Samantha Neumann Xiang Gao 
This work was supported by the National Institute of Neurological Disorders and Stroke at the National Institutes of Health(NINDS R03 NS09324501A1 and NINDS/NIH 1R21NS087235-01A1 to to X.G.).
Evidence from epidemiological studies suggest a relationship between cigarette smoking and low risk of Parkinson disease(PD).As a major component of tobacco smoke,nicotine has been proposed to be a substance for preve...
关键词：NICOTINE SMOKING DIET Gene-environment interactions Parkinson disease 
The biomarkers of immune dysregulation and inflammation response in Parkinson disease被引量：3
《Translational Neurodegeneration》2016年第1期131-136,共6页Li Chen Mingshu Mo Guangning Li Luan Cen Lei Wei Yousheng Xiao Xiang Chen Shaomin Li Xinling Yang Shaogang Qu Pingyi Xu 
This review was supported by research grants from the State Key Development Program for Basic Research of China(2011CB510000);the National Natural Science Foundation of China(81271428,81471292,U1503222 and 81430021);the keypoint Science Foundation of Guangdong of China(2015A030311021);a grant supported by technology project of Guangzhou(201604020152);a grant supported by assisting research project of science and technology for Xinjiang(201591160).
Parkinson’s disease(PD)is referring to the multi-systemicα-synucleinopathy with Lewy bodies deposited in midbrain.In ageing,the environmental and genetic factors work together and overactive major histocompatibility...
关键词：Parkinson’s disease α-synucleinopathy INFLAMMATION Biomarkers 
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