PARKINSON_DISEASE

作品数:125被引量:198H指数:7
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相关作者:余舒扬陈滢陈晓春王涛张巧俊更多>>
相关机构:首都医科大学附属北京天坛医院福建医科大学环境与疾病相关基因教育部重点实验室西安交通大学更多>>
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相关基金:国家自然科学基金北京市自然科学基金国家重点基础研究发展计划陕西省自然科学基金更多>>
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Correlations of transcranial sonography of substantia nigra characteristics with MRI iron deposition on substantia nigra in patients with Parkinson disease
《中国医学影像技术》2024年第8期1160-1163,共4页ZOU Quan CHEN Fei MENG Wenyu ZHENG Hong 
Objective To explore the correlations of transcranial sonography of substantia nigra(SN-TCS)characteristics with MRI iron deposition on substantia nigra in patients with Parkinson disease(PD).Methods Data of SN-TCS an...
关键词:Parkinson disease substantia nigra IRON ULTRASONOGRAPHY magnetic resonance imaging 
Substantia nigra hyperechogenicity in Parkinson disease patients with leucine-rich repeat kinase 2 variants in the Chinese Han population
《Chinese Medical Journal》2020年第12期1483-1484,共2页Kai Li Chen-Chen Gu Jin-Ru Zhang Hong Jin Yi-Lun Ge Jing Chen Ya-Ping Yang Fen Wang Cheng-Jie Mao Ying-Chun Zhang Chun-Feng Liu 
This work was supported by grants from the National Key R&D Program of China(No.2017YFC0909100);the National Natural Science Foundation of China(No.81801120);the Initial Scientific Research Fund at the Second Affiliated Hospital of Soochow University(No.SDFEYBS1702);Jiangsu Provincial Medical Key Discipline Project(No.ZDXKB2016022);Jiangsu Provincial social development projects(No.BE2018658 and BE2017653);Suzhou Clinical Research Center of Neurological Disease(No.Szzx201503).
To the Editor:Parkinson disease(PD)is the second most common neurodegenerative disease,and is characterized by both motor and non-motor symptoms.The leucine-rich repeat kinase 2(LRRK2)gene,characterized by different m...
关键词:PATIENTS CLINICAL MUTATION 
The prevalence of freezing of gait in Parkinson’s disease and in patients with different disease durations and severities被引量:9
《Chinese Neurosurgical Journal》2020年第2期92-102,共11页Hong-Liang Ge Xiao-Yong Chen Yuan-Xiang Lin Ting-Juan Ge Liang-Hong Yu Zhang-Ya Lin Xi-Yue Wu De-Zhi Kang Chen-Yu Ding 
Background:The prevalence rates of freezing of gait(FOG)in Parkinson’s disease(PD)vary widely,ranging from 14.0 to 55.1%.Our aim is to calculate the overall prevalence of FOG in all PD patients with different disease...
关键词:PREVALENCE FREEZING GAIT Parkinson disease 
Evaluation of cardiovascular risk in patients with Parkinson disease under levodopa treatment被引量:3
《Journal of Geriatric Cardiology》2016年第1期75-80,共6页Zeki Yuksel Gunaydln Fahriye Feriha Ozer Ahmet Karagoz Osman Bektas Mehmet Baran Karatas Ash Vural Adil Bayramoglu Abdullah Celik Mehmet Yaman 
BackgroundLevodopa 是在有 Parkinson 疾病(PD ) 的病人的中间的治疗的不可缺少的选择。因为 L-dopa 治疗被显示增加浆液 homocysteine 层次,为心血管的混乱的一个著名风险因素,有在 L-dopa 治疗下面的 PD 的病人将在为未来的增加的...
关键词:Aortic distensibility Aortic stiffness Cardiovascular risk HOMOCYSTEINE Parkinson disease 
Analysis of brain-stem auditory evoked potential and visual evoked potential in patients with Parkinson disease
《Neural Regeneration Research》2006年第5期449-452,共4页Qiaorong Deng Jianzhong Deng Yanmin Zhao Xiaohai Yan Pin Chen 
BACKGROUND: With the development of neuroelectrophysiology, it had been identified that all kinds of evoked potentials might reflect the functional status of corresponding pathway. Evoked potentials recruited in the ...
Exon Deletions of Parkin Gene in Patients with Parkinson Disease
《Journal of Huazhong University of Science and Technology(Medical Sciences)》2004年第3期262-265,共4页王涛 梁直厚 孙圣刚 曹学兵 彭海 刘红进 童萼塘 
ThisprojectwassupportedbygrantsfromthekeyprogramofthespecialscientificprojectofScientific&TechnologicAgencyofHubeiprovince(No.2001AA308B01)andthehygienicresearchprojectofHygienicAgencyofHubeiprovince(No.WJ01529).
Summary: Mutations in the parkin gene have recently been identified in familial and isolated patients with early-onset Parkinson disease (PD) and that subregions between exon 2 and 4 of the parkin gene are hot spots o...
关键词:Parkinson disease parkin gene deletive mutation 
Experimental Study of Serum Substantia Nigra Neuron Autoantibody and Its Effect in Parkinson Disease Patients被引量:4
《Journal of Huazhong University of Science and Technology(Medical Sciences)》2001年第4期280-282,共3页陈吉相 曹学兵 徐岩 孙圣刚 
To investigate the serum substantia nigra neuron autoantibody and its effect in the patients with Parkinson disease (PD), substantia nigra slices and a rat model of injection of serum from PD patients in unilateral si...
关键词:substantia nigra AUTOANTIBODY SERUM Parkinson disease 
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