Tenofovir amibufenamide(TMF)is a novel prodrug of tenofovir that demonstrates a promising safety and efficacy profile.A recent study by Peng et al compared TMF with tenofovir alafenamide in the treatment of chronic he...
Non-alcoholic fatty liver disease(NAFLD)has emerged as a global public health concern,affecting over one-quarter of the global population.It is closely associated with the prevalence of obesity and metabolic syndrome....
Supported by National Natural Science Foundation of China,No.82100599 and No.81960112;Jiangxi Provincial Department of Science and Technology,No.20242BAB26122;Science and Technology Plan of Jiangxi Provincial Administration of Traditional Chinese Medicine,No.2023Z021;Project of Jiangxi Provincial Academic and Technical Leaders Training Program for Major Disciplines,No.20243BCE51001.
In this editorial,we provide insights into the publication by Niu et al featured in the latest edition of the World Journal of Gastroenterology.Specifically,our focus was on exploring the potential of traditional Chin...
Supported by National Natural Science Foundation of China,No.82170593,No.81700503;the National Key Research and Development Program of China,No.2021YFC2700802.
The incidence rates of hepatocellular carcinoma(HCC)have increased in recent decades.Despite advancements in therapy and early diagnosis improving shortterm prognosis,long-term outcomes remain poor.Long noncoding RNAs...
Autophagy,a conserved cellular degradation process,is crucial for various cellular processes such as immune responses,inflammation,metabolic and oxidative stress adaptation,cell proliferation,development,and tissue re...
Nonalcoholic fatty liver disease(NAFLD)is the most rapidly growing contributor to liver mortality and morbidity.Hepatocellular injury in nonalcoholic steatohepatitis(NASH)is caused by an increase in metabolic substrat...
the National Natural Science Foundation of China,No.82070648;the Science and Technology Innovation Program of Hunan Province,No.2021SK4014.
Hepatic ischemia-reperfusion injury(HIRI)is the major complication of liver surgery and liver transplantation,that may increase the postoperative morbidity,mortality,tumor progression,and metastasis.The underlying mec...
National Natural Science Foundation of China,No.81900466;and Hunan Provincial Natural Science Foundation of China,No.2020JJ5307.
Chronic and recurrent inflammatory disorders of the gastrointestinal tract caused by a complex interplay between genetics and intestinal dysbiosis are called inflammatory bowel disease.As a result of the interaction b...
the National Natural Science Foundation of China,No.81901141;the Scientific Research Project of Hunan Provincial Health Commission,No.202204114480.
The coronavirus disease 2019(COVID-19)pandemic has been a serious threat to global health for nearly 3 years.In addition to pulmonary complications,liver injury is not uncommon in patients with novel COVID-19.Although...
Supported by the National Natural Science Foundation of China,No.31960236;the Talent Innovation and Entrepreneurship Project of Lanzhou City,No.2019-RC-34;the Lanzhou Cheng guan District Science and Technology Planning Project,No.2020SHFZ0029.
Primary sclerosing cholangitis(PSC)is an autoimmune disease characterized by chronic cholestasis,a persistent inflammation of the bile ducts that leads to sclerotic occlusion and cholestasis.Gut microbes,consisting of...