supported by the National Natural Science Foundation of China(No.81672209,81871769,82272550);the Chongqing Science and Technology Bureau(China)(No.cstc2021jcyj-bshX0214).
Cartilage development is controlled by the highly synergistic proliferation and differentiation of growth plate chondrocytes,in which the Indian hedgehog(IHH)and parathyroid hormone-related protein-parathyroid hormone...
NSFC grant(82170921,81771033);the Department of Science and Technology of Sichuan Province(2016JQ0054)to L.Z.;The Yunnan Provincial Department of Science and Technology-Kunming Medical University granted a basic research joint special fund project(202001AY070001-151)to J.Z.
PTH-related peptide(PTHr P) improves the bone marrow micro-environment to activate the bone-remodelling, but the coordinated regulation of PTHr P and transforming growth factor-β(TGFβ) signalling in TMJ-OA remains i...
Supported by the Agencia Nacional de Promoción Científica y Tecnológica;No. PICT-2013-1441;Consejo Nacional de Investigaciones Científicas y Técnicas;No. PIP11220150100350;Instituto Nacional del Cáncer Asistencia Financiera Ⅱ;RESOL 493/14, No. 2002-4395-14-1;Instituto Nacional del Cáncer Asistencia Financiera Ⅲ-2016-2017, RESOL-2016-1006-E-APN-MS;No. 2002-3862-16-1 CANCER;Universidad Nacional del Sur;No. PGI:24/B230 and No. PGI:24/B303;Fundación Alberto J. Roemmers of Argentina
BACKGROUND Parathyroid hormone-related peptide(PTHrP)plays a key role in the development and progression of many tumors.We found that in colorectal cancer(CRC)HCT116 cells,the binding of PTHrP to its receptor PTHR typ...