PYRIN

作品数：164被引量：457H指数：10
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相关领域：医药卫生更多>>
相关作者：韩蓉吴东明许颖郭兵肖瑛更多>>
相关机构：贵州医科大学空军军医大学南方医科大学成都医学院第一附属医院更多>>
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相关基金：国家自然科学基金新疆维吾尔自治区自然科学基金陕西省自然科学基金山东省医药卫生科技发展计划项目更多>>
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Jianpi Gushen Huayu decoction ameliorated diabetic nephropathy through modulating metabolites in kidney,and inhibiting TLR4/NF-κB/NLRP3 and JNK/P38 pathways被引量：3
《World Journal of Diabetes》2024年第3期502-518,共17页Zi-Ang Ma Li-Xin Wang Hui Zhang Han-Zhou Li Li Dong Qing-Hai Wang Yuan-Song Wang Bao-ChaoPan Shu-Fang Zhang Huan-Tian Cui Shu-Quan Lv 
Supported by the Scientific Foundation of Administration of Traditional Chinese Medicine of Hebei Province,China,No.2023257.
BACKGROUND Jianpi Gushen Huayu Decoction(JPGS)has been used to clinically treat diabetic nephropathy(DN)for many years.However,the protective mechanism of JPGS in treating DN remains unclear.AIM To evaluate the therap...
关键词：Diabetic nephropathy Jianpi Gushen Huayu Decoction Oxidative stress Inflammation Untargeted metabolomics Toll-like receptor 4/nuclear factor-kappa B/NOD-like receptor family pyrin domain containing 3 pathway c-Jun N-terminal kinase/P38-mediated apoptosis 
Long noncoding RNA X-inactive specific transcript regulates NLR family pyrin domain containing 3/caspase-1-mediated pyroptosis in diabetic nephropathy被引量：9
《World Journal of Diabetes》2022年第4期358-375,共18页Jia Xu Qin Wang Yi-Fan Song Xiao-Hui Xu He Zhu Pei-Dan Chen Ye-Ping Ren 
Supported by Natural Science Foundation of Shenzhen University General Hospital (SUGH2020QD011)
BACKGROUND NLRP3-mediated pyroptosis is recognized as an essential modulator of renal disease pathology.Long noncoding RNAs(lncRNAs)are active participators of diabetic nephropathy(DN).X inactive specific transcript(X...
关键词：Diabetic nephropathy PYROPTOSIS Renal tubular epithelial cell Long noncoding RNA X-inactive specific transcript microRNA-15b-5p Toll-like receptor 4 NLR family pyrin domain containing 3/caspase-1 pathway 
Thioredoxin interacting protein,a key molecular switch between oxidative stress and sterile inflammation in cellular response被引量：10
《World Journal of Diabetes》2021年第12期1979-1999,共21页Islam N Mohamed Luling Li Saifudeen Ismael Tauheed Ishrat Azza B El-Remessy 
Tissue and systemic inflammation have been the main culprit behind the cellular response to multiple insults and maintaining homeostasis.Obesity is an independent disease state that has been reported as a common risk ...
关键词：Thioredoxin interacting protein NOD-like receptor pyrin domain containing 3 INFLAMMASOME Interleukin 1b Inflammation Obesity High-fat diet ISCHEMIA REPERFUSION Oxidative stress 
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