Aim: To observe the rats’ learning and memory acquisition ability disturbance induced by BI-D1870. Methods: Male SD rats were randomly divided into control group, solvent control group and BI-D1870 group. The rats in...
National Natural Science Foundation of China (No.81273546);Shanghai Science and Technology Committee (No. 14DZ2294100).
BRAF and MEK inhibitors have shown remarkable clinical efficacy in BRAF-mutant melanoma;however, most patients develop resistance, which limits the clinical benefit of these agents. In this study, we found that the hu...