应用咪喹莫特(imiquimod,IMQ)诱导的银屑病小鼠模型以及五联因子(a mixture of five proinflammatory cytokines,M5)诱导的银屑病角质形成细胞模型,评价羧胺三唑(carboxyamidotriazole,CAI)对银屑病的治疗效果和可能机制。银屑病皮损面...
National Natural Science Foundation of China(grant numbers 32170923,82103011);Beijing Natural Science Foundation(grant number 7214248);CAMS Innovation Fund for Medical Sciences(grant number 2021-I2M-1-050);Youth Elite Scientists Sponsorship Program by CAST(grant number 2019QNRC001);Beijing Nova Program of Science and Technology(grant number Z191100001119049).
Dear Editor,In recent years,the rapid development of immunotherapy has brought survival benefits for lung squamous cell carcinoma(LUSC)patients who have rare treatment options.Nevertheless,there are still some patient...
Objective:Filaggrin(FLG)is a protein expressed in the epidermis and involved in the maintenance of the epidermal barrier.However,the expression and localization of FLG in the upper airway remain controversial.The pres...