SCNT

作品数：38被引量：118H指数：6
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相关领域：农业科学生物学更多>>
相关作者：吴燕妮廖世军张志人刘黎明许卫华更多>>
相关机构：西北农林科技大学吉林大学吉林农业大学甘肃农业大学更多>>
相关期刊：《Science China(Life Sciences)》《新材料产业》《Genes & Diseases》《中国兽医杂志》更多>>
相关基金：国家自然科学基金国家高技术研究发展计划国家重点基础研究发展计划国家教育部博士点基金更多>>
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Inhibition of Wnt activity improves peri-implantation development of somatic cell nuclear transfer embryos
《National Science Review》2023年第9期157-173,共17页Yanhe Li Caihong Zheng Yingdong Liu Jincan He Qiang Zhang Yalin Zhang Xiaochen Kou Yanhong Zhao Kuisheng Liu Dandan Bai Yanping Jia Xiaoxiao Han Yifan Sheng Jiqing Yin Hong Wang Shuai Gao Wenqiang Liu Shaorong Gao 
supported by the Ministry of Science and Technology of China(2021YFA1102900);the National Natural Science Foundation of China(31721003,31820103009,82022027,31970814,32270909 and 32200665);supported by the National Key R&D Project of China(2020YFA0113200,2021YFC2700300 and 2018YFC1003102);the 2115 Talent Development Program of China Agricultural University(to S.G.);the Youth Innovation Promotion Association of the Chinese Academy of Sciences(2020104);the Science and Technology Commission of Shanghai Municipality(19JC1415300 and 21JC1405500).
Somatic cell nuclear transfer(SCNT) can reprogram differentiated somatic cells into totipotency.Although pre-implantation development of SCNT embryos has greatly improved,most SCNT blastocysts are still arrested at th...
关键词：SCNT reprogramming implantation WNT naïve pluripotency primed pluripotency EPIBLAST single-cell RNA-seq epigenetic barrier 
Cell totipotency:molecular features,induction,and maintenance被引量：6
《National Science Review》2015年第2期217-225,共9页Falong Lu Yi Zhang 
supported by National Institutes of Health and Howard Hughes Medical Institute.YZ is an Investigator of the Howard Hughes Medical Institute
In mammals, pluripotent stem cells can give rise to every cell type of embryonic lineage, and hold great potential in regenerative medicine and disease modeling. Guided by the mechanism underlying pluripotency, plurip...
关键词：TOTIPOTENCY PLURIPOTENCY EPIGENETICS embryonic stem cell REPROGRAMMING somatic cell nuclear transfer(SCNT) 
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