supported by National Natural Science Foundation of China(32188101 and 81971976).
Hand,foot and mouth disease(HFMD),mainly caused by enterovirus 71(EV71),has frequently occurred in the Asia-Pacific region,posing a significant threat to the health of infants and young children.Therefore,research on ...
supported by the grants from the Henan Province Outstanding Youth Science Fund Project(No.242300421025);the National Natural Science Foundation of China(No.82271460);the Research Foundation of Henan Province(No.HNGD2022067);the National High-End Foreign Expert Recruitment Plan of China(No.G2022026006L);the Research Foundation of Xinxiang Medical University(No.XYBSKYZZ202202).
Endothelial dysfunction(ED)serves as the pathological basis for various cardiovascular diseases.Guanosine triphosphate cyclopyrrolone 1(GCH1)emerges as a pivotal protein in sustaining nitric oxide(NO)production within...
SMURF2(smad ubiquitination regulatory factor 2)属于HECT(homologous to E6AP C terminus)家族E3泛素连接酶,有研究报道SMURF2在不同类型癌症中发挥促癌或抑癌作用.本研究探讨了SMURF2在前列腺(癌)细胞中调节STAT1(signal transducer...
the JSPS Grant-in-Aid(C)grant number 17K11005;the JSPS bilateral Joint Research Project grant number 1007397 to T.K.,MEXT/JSPS grant number JP19K12218 to T.S.,MEXT/JSPS grant number JP15H05952(“Resonance Bio”)to T.S.and T.I.,and MEXT/JSPS KAKENHI grant number JP16H06280(“Advanced Bioimaging Support”)。
Transforming growth factor-β(TGF-β)and bone morphogenetic protein(BMP)play important roles in bone metabolism.Smad ubiquitination regulatory factors(Smurfs)regulate TGF-β/BMP signaling via ubiquitination,resulting ...