supported by NIH CORE Grant P30 EY08098 to the Department of Ophthalmology,University of Pittsburgh,the Eye and Ear Foundation of Pittsburgh (to KCC)。
SRY-related HMG-box(Sox) transcription factors are known to regulate central nervous system development and are involved in several neurological diseases.Post-translational modification of Sox proteins is known to alt...
supported by the National Natural Science Foundation of China(General Program),No.316781246(to DYZ);the Science and Technology Fund of Health Planning Commission of Binhai New Area of Tianjin of China,No.2011BHKY008,2012BWKZ002(to KY);the National Key Research and Development Program of China,No.2016YFC1101600(to DYZ)
Small ubiquitin-like modifiers (SUMOs) have been shown to regulate axonal regeneration, signal transduction, neuronal migration, and myelination, by covalently and reversibly attaching to the protein substrates during...
Recently there have been exciting research advances in neuroprotective therapies for ischemic stroke. In the past, the search for neu- roprotective agents has been fraught with failure at the clinical trials stage due...
Glaucoma and other optic neuropathies result in optic nerve degeneration and the loss of retinal ganglion cells(RGCs)through complex signaling pathways.Although the mechanisms that regulate RGC development remain un...