目的:观察运动后小鼠脑室室管膜下区(subventricular zone,SVZ)蛋白酶体活性变化,探讨运动促进神经发生的机制。方法:应用荧光分光光度法检测新生小鼠(Postnantal day 0,P0)、成年小鼠(Postnantal day 90,P90)及老年小鼠(Postnantal day...
Neurogenesis from inner brain neural stem cells (NSCs) is a process which takes place continuously in mammals through- out their life. However, the main ontogenic difference is the intensity of neurogenesis, which c...
This study was supported by China National Key Research and Development Program (2016YFA0100801 YS), and the National Natural Science Foundation of China (Grant Nos. 8133030 YS and 31620103904 YS), and grants: 2016YFC102705 YS; 2014BAI04B07 WZL; 81470715 YS;TJ1504219036 WZL.
Aging associated cognitive decline has been linked to dampened neural stem/progenitor cells (NSC/NPCs) activities manifested by decreased proliferation, reduced propensity to produce neurons, and increased different...