supported by the National Natural Science Foundation of China(82173808,U21A20419,82270500);Natural Science Foundation of Guangdong Province(2021B1515020100,China);Guangzhou Basic and Applied Basic Research Project(202206080007,China);Local Innovative and Research Teams Project of Guangdong Pearl River Talents Program(2017BT01Y093,China);Guangdong Provincial Key Laboratory of Construction Foundation(2017B030314030,China);Academic promotion program of Shandong First Medical University(2019LJ003,China).
The clinical utilization of doxorubicin(Dox)in various malignancies is restrained by its major adverse effect:irreversible cardiomyopathy.Extensive studies have been done to explore the prevention of Dox cardiomyopath...