TOLL-LIKE

作品数:156被引量:883H指数:15
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相关领域:医药卫生更多>>
相关作者:黄志新富宁刘艳君韩勇彬胡大海更多>>
相关机构:首都医科大学中国医科大学广州中医药大学深圳市中医院更多>>
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相关基金:国家自然科学基金国家重点基础研究发展计划国家教育部博士点基金内蒙古自治区自然科学基金更多>>
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Bupleurum polysaccharides ameliorated renal injury in diabetic mice associated with suppression of HMGB1-TLR4 signaling被引量:16
《Chinese Journal of Natural Medicines》2019年第9期641-649,共9页LIU Zhen-Zhen WENG Hong-Bo ZHANG Li-Jie PAN Ling-Yu SUN Wei CHEN Hai-Xia CHEN Mei-Yu ZENG Tao ZHANG Yun-Yi CHEN Dao-Feng LI Hong 
funded by the National Natural Science Foundation of China(Nos.81673658,81274165 and 30925042);Ministry of Science and Technology of China(No.2018ZX09735003-002);the Science and Technology Commission of Shanghai Municipality(No.12JC1400800)
Bupleurum polysaccharides(BPs)is isolated from Bupleurum smithii var.parvifolium,a key traditional Chinese medicine.The study was to investigate the effects of BPs on diabetic kidney injury.After two intraperitoneal i...
关键词:RENAL injury Bupleurum:High-mobility group box TOLL-LIKE receptor 4 Inflammation RENAL FIBROSIS POLYSACCHARIDES 
Mapping Toll-Like Receptor Signaling Pathway Genes of Zhikong Scallop(Chlamys farreri) with FISH被引量:3
《Journal of Ocean University of China》2015年第6期1075-1081,共7页ZHAO Bosong ZHAO Liang LIAO Huan CHENG Jie LIAN Shanshan LI Xuan HUANG Xiaoting BAO Zhenmin 
financially supported by the National Natural Science Foundation of China(31270047);the National High Tech R&D Program(2012AA10A410);the National Basic Research Program of China(2010CB126402);the National Key Technology R&D Program of China(2011BAD45B01 and 2011BAD13B05)
Toll-like receptor(TLR) signaling pathway plays a pivotal role in the innate immune system. Studies on TLR signaling pathway genes in Zhikong scallop(Chlamys farreri) have mainly focused on sequence analysis and expre...
关键词:IMMUNOGENETICS CHLAMYS FARRERI TLR signaling pathway FISH 
单核/巨噬细胞表面髓样细胞表达激发受体(TREM)-1分子的促炎作用及其调控机制
《中华微生物学和免疫学杂志》2015年第5期391-394,共4页黄子雄 张昕玮 葛青 
973项目(2011CB711000);国家自然科学基金(31270935,81471525);北京市自然科学基金(5152010)
巨噬细胞是一类重要的免疫调节和免疫效应细胞。它们存在于所有组织中,具有极大的可塑性和功能多样性,是免疫应答、组织修复、维持机体稳态的关键调节者。巨噬细胞表达各种受体,这些受体是巨噬细胞实现多种功能的基础。巨噬细胞能通...
关键词:病原体相关分子模式 模式识别受体 巨噬细胞表面 细胞表达 receptor 免疫球蛋白超家族 固有免疫应答 TOLL-LIKE 
Critical role of Toll-like receptor signaling in NK cell activation
《Chinese Science Bulletin》2012年第24期3192-3202,共11页GUO Qie ZHANG Cai 
supported by the National Natural Science Foundation of China (90713033, 30901307, and 30772497);the National Basic Research Program of China (2007CB815800)
Toll-like receptors (TLRs) and NK cell receptors are the most important receptor superfamilies in innate immunity. TLRs act as the sensor of external pathogens, while NK cells detect alterations in endogenous protein ...
关键词:TOLL样受体 NK细胞 信号通路 活化 免疫反应 细胞受体 适应性反应 微生物感染 
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