云南高校图书馆联盟文献共享服务平台- TRANILAST

TRANILAST: 作品数：16被引量：15H指数：2; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：曹阳魏厚仁沈联芳笪邦红吴冬辉更多>>; 相关机构：华中科技大学中国科学院武汉物理研究所中国科学院华西医科大学更多>>; 相关期刊：《International Journal of Ophthalmology(English edition)》《Frigid Zone Medicine》《波谱学杂志》《物理化学学报》更多>>; 相关基金：国家自然科学基金广东省自然科学基金更多>>

Tranilast在角膜碱烧伤治疗中的潜在作用: 《眼科学》2023年第3期101-107,共7页林雅娜杨程成刘洋; 角膜碱烧伤是临床上常见的眼外伤类型,致盲率极高,其发生机制涉及角膜基质细胞、炎性细胞浸润、角膜胶原纤维降解、各种细胞因子及其相互作用。积累的证据表明,Tranilast具有广泛的药理特性,如抗炎、减轻纤维化和免疫调节作用。本文综述...; 关键词：TRANILAST 角膜碱烧伤胶原降解炎症

Tranilast treats cold-related hypertension by reducing the expression of NLRP3 inflammasome被引量：1: 《Frigid Zone Medicine》2021年第2期95-101,共7页Hui Yu Yun Zhou Yu Duan Yunlong Gao Ning Fang Jiawei Zhang Yue Li; Objective:Cold exposure is associated with increased prevalence of hypertension and the related severe cardiovascular events.Aberrant activation of the nucleotide-binding oligomerization domain-like receptor protein 3...; 关键词：cold exposure blood pressure NLRP3 TRANILAST

Intravesical Infusion of Budesonide Foam Improves Symptoms in a Bladder Pain Syndrome/Interstitial Cystitis Rat Model被引量：1: 《Open Journal of Urology》2020年第5期123-133,共11页Kimio Sugaya Saori Nishijima Katsuhiko Noguchi Shiho Okitsu Katsumi Kadekawa Kennosuke Karube Hideyuki Yamamoto; Purpose: Since intravesically administered steroid therapy may treat bladder pain syndrome/interstitial cystitis (BPS/IC) with fewer side effects than the current treatment of orally administered steroids, we investig...; 关键词：BLADDER Pain BUDESONIDE Interstitial CYSTITIS Rats TRANILAST

Tranilast inhibits TGF-β-induced collagen gel contraction mediated by human corneal fibroblasts被引量：1: 《International Journal of Ophthalmology(English edition)》2018年第8期1247-1252,共6页Ye Liu Xiao-Jing Zhao Xiao-Shuo Zheng Hui Zheng Lei Liu Ling-Bin Meng Qin Li Yang Liu; Supported by the National Science Foundation of China (No.81770889);the Natural Science Foundation of Guangdong Province (No.2017A030313774);the Research Fund of Jilin Provincial Science and Technology Department to Yang Liu (International Cooperation Item, No.20160414055GH); AIM： To determine if tranilast affects human corneal fibroblast（HCFs） contraction.METHODS： HCFs cultured in a three-dimensional type I collagen gel were treated with or without transforming growth factor beta（TGF...; 关键词：TRANILAST transforming growth factor beta corneal fibroblast corneal wound healing

Inhibitory effects of resveratrol on human mast cell degranulation, cytokine, chemokine and leukotriene release被引量：1: 《Open Journal of Immunology》2012年第4期187-194,共8页Adriana Catalli Clayton MacDonald Priyanka Pundir Marianna Kulka; Resveratrol, a polyphenol abundant in peanuts, red wine and the skin of grapes, has been shown to have anti-cancer, anti-oxidant and anti-inflammatory activities, and may also have beneficial effects on allergic infla...; 关键词：Mast Cells RESVERATROL TRANILAST IgE Substance P LEUKOTRIENES

Antagonistic Effects of Tranilast on Proliferation and Collagen Synthesis Induced by TGF-β_2 in Cultured Human Trabecular Meshwork Cells: 《Journal of Huazhong University of Science and Technology(Medical Sciences)》2004年第5期490-492,496,共4页笪邦红曹阳魏厚仁陈志新水迎波李忠玉; ThisprojectwassupportedbyagrantfromtheNationalNaturalSciencesFoundationofChina (No .38970 75 8) .; Whether tranilast had antagonistic effect on proliferation inhibition and collagen synthesis promotion induced by TGF-β 2 in cultured human trabecular meshwork cells was investigated. Suspension of 1×104 cultured h...; 关键词：transforming growth factor HUMAN trabecular meshwork cultured cell PROLIFERATION COLLAGEN

Tranilast对人眼小梁细胞胶原合成的抑制被引量：1: 《眼科研究》2003年第4期353-354,共2页曹阳魏厚仁笪邦红; 国家自然科学基金资助(38970758); 目的观察tranilast对体外培养人眼小梁细胞胶原合成的影响.方法体外培养第3～5代牛眼小梁细胞经0 μg/ml(对照组)、12.5、25和50 μg/ml tranilast处理后,采用3H-脯氨酸掺入及液体闪烁测量技术观察tranilast对体外培养人眼小梁细胞胶原...; 关键词：TRANILAST 人眼小梁细胞胶原合成抑制原发性开角型青光眼

Tranilast抑制TGF-β_2对人眼小梁细胞胶原合成的促进作用被引量：2: 《中国实用眼科杂志》2003年第7期555-557,共3页曹阳魏厚仁笪邦红; 国家自然科学基金资助项目 (38970 758); 目的 :观察tranilast对转化生长因子 -β2 (Transforminggwowthfactor -β2 ,TGF -β2 )促进体外培养人眼小梁细胞胶原合成作用的影响。方法 :采用3 H -脯氨酸掺入及液体闪烁测量技术观察 0 μg·ml-1(对照组 )、 12 5 μg·ml-1、 2 5...; 关键词：TRANILAST TGF—β2 小梁细胞胶原合成细胞培养青光眼转化生长因子

Tranilast对滤过泡的影响: 《国外医学（眼科学分册）》2002年第4期254-255,共2页李建军; 关键词：青光眼滤过术青光眼小梁切除术 TRANILAST 滤过泡

Tranilast对TGF-β_2抑制人眼小梁细胞生长作用的影响被引量：1: 《眼视光学杂志》2002年第2期92-94,共3页曹阳魏厚仁笪邦红; 国家自然科学基金资助项目 (3 8970 75 8); 目的 :观察tranilast对转化生长因子 β2 (transform inggrowthfactor β2 ,TGF β2 )抑制体外培养人眼小梁细胞生长作用的影响。方法 :采用MTT法观察 0 μg/ml、12 .5 μg/ml、2 5μg/ml和 5 0 μg/mltranilast对 3.2ng/mlTGF β2 抑...; 关键词：TRANILAST TGF-Β2 小梁细胞原发性开角型青光眼细胞培养

TRANILAST