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UC: 作品数：1644被引量：3281H指数：19; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：沈洪欧阳钦王新月郑红斌闫曙光更多>>; 相关机构：辽宁中医药大学湖南中医药大学广州中医药大学南京医科大学更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划国家高技术研究发展计划江苏省自然科学基金更多>>

Neuroserpin alleviates cerebral ischemia-reperfusion injury by suppressing ischemia-induced endoplasmic reticulum stress: 《Neural Regeneration Research》2026年第1期333-345,共13页Yumei Liao Qinghua Zhang Qiaoyun Shi Peng Liu Peiyun Zhong Lingling Guo Zijian Huang Yinghui Peng Wei Liu Shiqing Zhang István Adorján Yumi Fukuzaki Eri Kawashita Xiao-Qi Zhang Nan Ma Xiaoshen Zhang Zoltán Molnár Lei Shi; supported in part by the National Key Research&Development Program of China,No. 2022YFA1104900 (to LS);the National Natural Science Foundation of China,Nos. 82371175, 82071535 (both to LS), 82101614 (to YP);the International Science and Technology Cooperation Projects of Guangdong Province,No. 2023A0505050121 (to LS);Guangdong Basic and Applied Basic Research Foundation,Nos. 2022B1515130007 (to LS), 2023A1515030012 (to SZ), 2022A1515010666 (to WL);the Science and Technology Program of Guangzhou,Nos. 202102070001 (to LS), 202201010041 (to YP);Shenzhen Basic Research Grant,Nos. JCYJ20200109140414636, JCYJ20230807145103007 (both to WL);awarded a Royal Society Newton Advanced Fellowship,No. AOMS-NAF0051003;in collaboration with Zoltán Molnár,Department of Physiology,Anatomy and Genetics,University of Oxford (2017–2021)。; Neuroserpin, a secreted protein that belongs to the serpin superfamily of serine protease inhibitors, is highly expressed in the central nervous system and plays multiple roles in brain development and pathology. As a...; 关键词：endoplasmic reticulum stress ischemia-reperfusion injury NEURON neuronal apoptosis NEUROPROTECTION NEUROSERPIN protein synthesis secretory protein stroke transcriptomic analysis

Gamma-induced positron beam generation at SLEGS: 《Nuclear Science and Techniques》2025年第5期1-10,共10页Sheng Jin Zi-Rui Hao Long-Xiang Liu Kai-Jie Chen Yu-Xuan Yang Hang-Hua Xu Yue Zhang Qian-Kun Sun Zhen-Wei Wang Gong-Tao Fan Hong-Wei Wang; supported by the National Key Research and Development program(Nos.2022YFA1602404,2023YFA1606901);the National Natural Science Foundation of China(Nos.12275338,12388102,and U2441221);the Key Laboratory of Nuclear Data foundation(JCKY2022201C152)xm。; Energy-variable gamma-rays are produced in Laser Compton Slant-scattering mode at the Shanghai Laser Electron Gamma Source(SLEGS),a beamline of the Shanghai Synchrotron Radiation Facility(also called Shanghai Light So...; 关键词：Shanghai Laser Electron Gamma Source Monte Carlo simulation Nondestructive testing POSITRON GEANT4

溃疡性结肠炎患者LncRNABC012900/IFNG-AS1的表达水平与其临床意义: 《中文科技期刊数据库(全文版)医药卫生》2025年第4期017-021,共5页董侠威何思民张海莲孟云超张启芳; 广西自然科学基金(No.81560094);广西壮族自治区卫生健康委员会计划课题(No.Z20191039);广西桂林市科学研究与技术开发计划课题(NO.20190218-8-2)。; 通过检测溃疡性结肠炎(Ulcerative Colitis,UC)患者血清及肠黏膜组织中LncRNA BC012900和LncRNA IFNG-AS1的表达水平,探讨其对UC的诊断价值。方法选择47例确诊的UC患者作为UC组,另选择同期20例健康体检者作为对照组,采集入院时的血清...; 关键词：溃疡性结肠炎(UC) 长链非编码RNA(LncRNA) 内镜诊断

A Genome-wide association study identifies candidate genes for heat tolerance in adult cucumber plants: 《Horticultural Plant Journal》2025年第2期774-787,共14页Zaizhan Wang Shaoyun Dong Yanyan Liu Diane M.Beckles Caixia Li Jianan Han Yi Zhang Xiaoping Liu Jiantao Guan Xingfang Gu Han Miao Shengping Zhang; supported by Beijing Joint Research Program for Germplasm Innovation and New Variety Breeding(Grant No.G20220628003-03);Chongqing Municipal People's Government and Chinese Academy of Agricultural Sciences strategic cooperation project,Key-Area Research and Development Program of Guangdong Province(Grant No.2020B020220001);the Earmarked Fund for Modern Agro-industry Technology Research System(Grant No.CARS-23);Science and Technology Innovation Program of the Chinese Academy of Agricultural Science(Grant No.CAAS-ASTIP-IVFCAAS);Central public-interest Scientific Institution Basal Research Fund(Grant No.Y2017PT52);the Key Laboratory of Biology and Genetic Improvement of Horticultural Crops,Ministry of Agriculture,P.R.China。; Heat stress causes overgrowth,leaf dryness and fruit malformation,which negatively impacts cucumber quality and yield.Yet,in spite of the devastating consequences of this abiotic stress,few genes for heat tolerance in...; 关键词：Cucumis sativus L. Heat tolerance GWAS Candidate gene analysis

基于肠道菌群探讨刺糖酸性多糖对UC小鼠的影响: 《食品与发酵工业》2025年第7期74-81,共8页高霜陈章浩李进发干振常军民; 国家自然科学基金资助项目(82060756)。; 研究刺糖酸性多糖对葡聚糖硫酸钠(dextran sulphate sodium, DSS)诱导的溃疡性结肠炎(ulcerative colitis, UC)小鼠的改善作用,并分析其对小鼠肠道菌群的影响。将40只SPF级雄性C57BL/6小鼠随机分为对照组、模型组、美沙拉嗪组(100 mg/kg...; 关键词：刺糖酸性多糖溃疡性结肠炎疾病活动指数评分炎症因子肠道菌群

中医药对炎症性肠病的治疗作用: 《天然产物研究与开发》2025年第4期792-793,共2页张芳; 炎症性肠病(inflammatory bowel disease,IBD)是一类以慢性肠道炎症为特征的疾病,主要包括克罗恩病(Crohn′s disease,CD)和溃疡性结肠炎(ulcerative colitis,UC)。IBD机制复杂、病因不明,涉及遗传易感性、肠道菌群失调、免疫系统异常...; 关键词：炎症性肠病促炎因子 UC IBD CD

活动期UC患者超声内镜检查的相关参数与其病情程度的关系: 《中文科技期刊数据库(引文版)医药卫生》2025年第3期120-123,共4页王鑫夏本林徐天翠罗志珍; 探讨活动期UC患者超声内镜检查的相关参数与其病情程度的关系。方法本研究共选取40例在2021年8月至2022年8月期间在我院就诊的UC患者作为观察组,并根据超声内镜检查结果将其分为静止期UC组(超声内镜结果显示黏膜下血管呈不规则性排列...; 关键词：溃疡性结肠炎活动期超声内镜检查相关参数病情程度

广藿香酮对溃疡性结肠炎的抗炎作用及其作用机制研究: 《成都大学学报(自然科学版)》2025年第1期1-8,共8页李美慧黄友付豪吴孟霞张月傅舒张文静张臻傅超美; 国家自然科学基金联合基金重点项目(U21A20409);四川省科技厅科技计划项目(2021YJ0251);四川省中医药管理局中医药科研专项(2021MS109);成都中医药大学杏林学者青年学者专项(QNXZ2019031)。; 研究广藿香酮对溃疡性结肠炎(UC)的作用机制.使用葡聚糖硫酸钠建立UC小鼠模型,共有30只雄性ICR小鼠随机分为对照组、模型组、广藿香酮高剂量组(80 mg/kg)、广藿香酮中剂量组(40 mg/kg)和广藿香酮低剂量组(20 mg/kg);药物连续干预7 d后,...; 关键词：广藿香酮 UC 转录组学网络药理学分子对接分子动力学模拟

Injury/ischemia-induced stem cells: up-to-date knowledge and future perspectives for neural regeneration: 《Neural Regeneration Research》2025年第3期797-798,共2页Takayuki Nakagomi; partially supported by the Japan Society for the Promotion of Science (JSPS) KAKENHI (15K06723;18K07380);the Japan Agency for Medical Research and Development (AMED) (21nk0101538h0002) (to TN)。; Brain injuries like ischemic stroke induce endogenous stem cell production. Although the precise traits of stem cells in pathological brains remain unclear, we previously demonstrated that injury/ischemia-induced stem...; 关键词：ISCHEMIA INJURIES

布拉氏酵母菌联合柳氮磺吡啶肠溶片治疗UC的临床研究: 《中国肛肠病杂志》2025年第2期44-46,共3页李鸿儒辛祎冯鹏飞王永辉; 河南省高等学校重点科研项目(22A310002);河南省医学科技攻关计划项目(LHGJ20231008)。; 目的:探讨布拉氏酵母菌联合柳氮磺吡啶肠溶片治疗溃疡性结肠炎(UC)的临床疗效及对肠黏膜屏障功能的影响。方法:将2023年2月至2024年2月我院收治的符合入组标准的80例UC患者随机分为观察组和对照组,各40例。对照组接受柳氮磺吡啶治疗,观...; 关键词：溃疡性结肠炎布拉氏酵母菌柳氮磺吡啶疗效

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