the Natural Science Foundation of Liaoning Province,No.2023-MS-149.
BACKGROUND As a novel endogenous anti-angiogenic molecule, vasohibin 1(VASH1) is not only expressed in tumor stroma, but also in tumor tissue. Moreover, studies have shown that VASH1 may be a prognostic marker in colo...
Supported by Natural Science Fund Project in Jiangsu Province(No.BK20180380);Nanjing Health Commission(No.YKK18260)。
Ischemic and neovascular disease is one of the most difficult ocular diseases to deal with nowadays.Redundancy,poor visual acuity and decreased life quality are bothering patients and ophthalmologists for decades.Afte...
In the initial published version of this article,there was an inadvertent omission from the Acknowledgements that work in the lab of MB is supported by grants from Danish Cancer Society Scientific Committee(KBVU;R146-...
We thank the staffs of Shanghai Synchrotron Radiation Facility at beam lines BL17U1, BL18U1, and BL19U1 for assistance in data collection and processing;supported by the "Strategic Priority Research Program" of the Chinese Academy of Sciences (Grant No. XDB19000000);National Natural Science Foundation of China Grants 31570737 and 31770806 (to C.X.), 31500601 (to S.L), and 31501093 (to H.Y.) CX;is also supported by the Major/lnnovative Program of the Development Foundation of the Hefei Center for Physical Science and Technology (2018CXFX007) and the ^Thousand Young Talent program";H.Y. is supported by China Postdoctoral Science Foundation Grant (2015M5805470);The work was also supported by the Fundamental Research Funds for the Central Universities (WK2070080001);We would like to thank Martina Barisic for excellent technical support;We thank J. Nilsson, S. Geley, R. Medema, P. Draber and I. Cheeseman for sharing reagents and E. Vitiello for her help with the polar plots;We also thank Dr. Zhongliang Zhu for his assistance in processing the datasets of SeMet crystals.
α-Tubulin detyrosination, largely catalyzed by vasohibins, is involved in many microtubule (MT)-related cellular events. In this study, we identified a core heterodimeric complex of human small vasohibin-binding prot...