supported by Grants from the National Science Foundation of China(81771205,91632113,81973963,81674085,and 81674075);the National Key Research and Development Program of China(2018YFC1704600);the Natural Science Foundation and Major Basic Research Program of Shanghai(16JC1420500 and 16JC1420502);the Chinese Academy of Medical Sciences Innovation Fund for Medical Sciences(2017-I2M-3-008)。
Pain on the body surface can accompany disorders in the deep tissue or internal organs. However, the anatomical and physiological mechanisms are obscure.Here, we provided direct evidence of axon bifurcation in primary...
supported by grants from the National Natural Science Foundation of China (81471137, 31730040, and 81771187);the Priority Academic Program Development of Jiangsu Higher Education Institutions of China
Chronic visceral hypersensitivity is an important type of chronic pain with unknown etiology and pathophysiology. Recent studies have shown that epigenetic regulation plays an important role in the development of chro...
supported by grants from the National Natural Science Foundation of China(81471137,31730040,and 81500952);the Priority Academic Program Development of Jiangsu Higher Education Institutions of China
The pathophysiology of visceral pain in patients with irritable bowel syndrome remains largely unknown.Our previous study showed that neonatal maternal deprivation(NMD) does not induce visceral hypersensitivity at the...
Objective Cisplatin exerts its cytotoxic effect through distinct DNA lesions,leading to peripheral neuropathy.The risk of sensory neuropathy is a common problem during cancer treatment with cisplatin,leading to somati...