Supported by the Spanish Ministry of Education and Science,No.SAF2010-15896,No.SAF2013-43284-P and No.SAF2017-82261-P.
BACKGROUND The challenges for inflammatory bowel disease(IBD)diagnostics are to discriminate it from gut conditions with similar symptoms such as irritable bowel syndrome(IBS),to distinguish IBD subtypes,to predict di...
Supported by the Program of International S&T Cooperation,No.2014DFA31850;National Natural Science Foundation of China,No.81870379.
Genetic polymorphism is associated with irritable bowel syndrome(IBS)in terms of susceptibility and clinical manifestations.Previous studies have shown that genetic polymorphism might play a key role in the onset and ...
Supported by the National Key Technology Support Program during “12th Five-Year Plan”period of China,No.2014BAI08B00;the Leapforward Development Program for Beijing Biopharmaceutical Industry(G20),No. Z171100001717008.
BACKGROUND Visceral hypersensitivity and psychological performance are the main pathophysiological mechanisms of irritable bowel syndrome(IBS).Previous studies have found that cholecystokinin(CCK)can enhance colon mov...
Despite the bi-directional interaction between gut microbiota and the brain not being fully understood,there is increasing evidence arising from animal and human studies that show how this intricate relationship may f...
Gastrointestinal(GI)ultrasound(GIUS)is valuable in the evaluation of GI diseases such as inflammatory bowel disease,but its use in functional GI disorders(FGIDs)is largely unknown although promising.In order to review...
Research supported by New Zealand College of Chinese Medicine
Irritable bowel syndrome(IBS)is a relatively common condition characterized by abdominal pain,among other symptoms,that significantly impacts the quality of life of IBS patients.Therapeutic treatment of IBS results in...
Objective: To evaluate the efficacy and safety of Tongxiening Granules(痛泻宁颗粒, TXNG) in the treatment of irritable bowel syndrome with predominant diarrhea(IBS-D). Methods: A randomized, double-blind, double-dummy...
Supported by Shanghai Three-year Action Plan for Accelerating the Development of Traditional Chinese Medicine,No.ZY(2018-2020)-CCCX-2002-01
BACKGROUND Irritable bowel syndrome(IBS)and functional constipation(FC)are two commonly encountered functional gastrointestinal disorders in clinical practice and are usually managed with Western medicines in cooperat...
the National Key Technology Support Program for the “12th Five-Year Plan” of China,No.2014BAI08B00;the Research Projects on Biomedical Transformation of China-Japan Friendship Hospital,No.PYBZ1815
BACKGROUND Fecal metabolites are associated with gut visceral sensitivity,mucosal immune function and intestinal barrier function,all of which have critical roles in the pathogenesis of irritable bowel syndrome(IBS).H...
Supported by the National Nature Science Foundation of China,No.81572243;Scientific Research Funds Project of Liaoning Education Department,No.LJC2019ST02
BACKGROUND Irritable bowel syndrome(IBS)is a common digestive system disease with a high incidence rate and is common in women.The cause of IBS remains unclear.Some studies have shown that mental and psychological dis...