AXIS

作品数：1101被引量：2797H指数：21
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Gut–brain axis and environmental factors in Parkinson's disease:bidirectional link between disease onset and progression
《Neural Regeneration Research》2025年第12期3416-3429,共14页Soo Jung Park Kyung Won Kim Eun Jeong Lee 
supported by the National Research Foundation(NRF)of Korea(2022R1C1C1005741 and RS-2023-00217595)。
Parkinson's disease has long been considered a disorder that primarily affects the brain,as it is defined by the dopaminergic neurodegeneration in the substantia nigra and the brain accumulation of Lewy bodies contain...
关键词：gut inflammation gut microbiome gut-brain axis micro/nano-plastics Parkinson’s disease Α-SYNUCLEIN 
Longitudinal assessment of peripheral organ metabolism and the gut microbiota in an APP/PS1 transgenic mouse model of Alzheimer’s disease
《Neural Regeneration Research》2025年第10期2982-2997,共16页Hongli Li Jianhua Huang Di Zhao Lemei Zhu Zheyu Zhang Min Yi Weijun Peng 
financially supported by the National Natural Science Foundation of China,No.823 74552 (to WP);the Science and Technology Innovation Program of Hunan Province,No.2022RC1220 (to WP);the Natural Science Foundation of Hunan Province of China,Nos.2020JJ4803 (to WP),2022JJ40723 (to MY);the Scientific Research Launch Project for New Employees of the Second Xiangya Hospital of Central South University (to MY)
Alzheimer’s disease not only affects the brain,but also induces metabolic dysfunction in peripheral organs and alters the gut microbiota.The aim of this study was to investigate systemic changes that occur in Alzhei...
关键词：Alzheimer’s disease APP/PS1 mice brain-kidney axis gut microbiota heart-brain axis liver-brain axis lung-brain axis microbiota-gut-brain axis peripheral organ metabolism spleen-brain axis 
The gut-eye axis:from brain neurodegenerative diseases to age-related macular degeneration
《Neural Regeneration Research》2025年第10期2741-2757,共17页Qianzi Jin Suyu Wang Yujia Yao Qin Jiang Keran Li 
supported by the National Natural Science Foundation of China,No.82171080;Nanjing Medical Science and Technology Development Project,No.YKK23264;Postgraduate Research&Practice Innovation Program of Jiangsu Province,Nos.JX10414151,JX10414152(all to KL)。
Age-related macular degeneration is a serious neurodegenerative disease of the retina that significantly impacts vision.Unfortunately,the specific pathogenesis remains unclear,and effective early treatment options are...
关键词：age-related macular degeneration biological agents blinding eye disease dietary nutrition fecal microbial transplantation gut-eye axis intestinal flora METABOLITE MICROECOLOGY neurodegenerative disease 
Bidirectional regulation of the brain-gut-microbiota axis following traumatic brain injury被引量：1
《Neural Regeneration Research》2025年第8期2153-2168,共16页Xinyu You Lin Niu Jiafeng Fu Shining Ge Jiangwei Shi Yanjun Zhang Pengwei Zhuang 
supported by the National Natural Science Foundation of China,No.82174112(to PZ);Science and Technology Project of Haihe Laboratory of Modern Chinese Medicine,No.22HHZYSS00015(to PZ);State-Sponsored Postdoctoral Researcher Program,No.GZC20231925(to LN)。
Traumatic brain injury is a prevalent disorder of the central nervous system.In addition to primary brain parenchymal damage,the enduring biological consequences of traumatic brain injury pose long-term risks for pati...
关键词：traumatic brain injury brain-gut-microbiome axis gut microbiota NEUROIMMUNE immunosuppression host defense vagal afferents bacterial infection dorsal root ganglia nociception neural circuitry 
Prophylactic effects of edible Lilium-egg yolk compound powder on depression-like behaviors in rats exposed to chronic unpredictable mild stress:a role of gut-brain axis
《Food Science and Human Wellness》2025年第3期1169-1184,共16页Yu Huang Yuxin Luo Sainan Tian Mengzhou Xie Liang Li Mingxing Jiang Zhiying Yuan 
financial support of the Natural Science Foundation of Hunan Province(2023JJ60481);the Natural Science Foundation of Changsha Municipality(kq2208181);the Hunan Provincial Department of Education’s Outstanding Youth Science Research Project(22B0360);the Hunan Provincial Department of Education’s Science Research Project(22C0191);the National Ministry of Agriculture’s Edible Lily Longshan Comprehensive Experimental Station Project(CARS-21);the Hunan University of Chinese Medicine Graduate Innovation Project(2023CX157)。
The incidence rate and harmfulness of depression are increasing yearly,and the research on the antidepressant effect of regulating the intestinal microecology balance has attracted widespread attention.The purpose of ...
关键词：Depression “Microbiota-gut-brain”axis Intestinal mucosal GR/BDNF/NPY LILIUM Egg yolk 
Tremella polysaccharide mitigates high-fat diet-induced anxiety-like behavior through the microbiota-gut-brain axis
《Food Science and Human Wellness》2025年第3期1062-1079,共18页Haicui Wu Shuyu Chen Wenxiu Zhang Yuqing Lub Jiayi Zheng Jinhui Chang Jiachi Chiou 
supported by the Seed Fund of Research Institute of Future Food(1-CD54)。
High-fat diet(HFD)consumption induces gut microbiota dysbiosis and neuropsychiatric disorders,including anxiety.Previous research found that Tremella polysaccharide(TP)exhibited neuroprotective effects in vitro and in...
关键词：Tremella polysaccharide High-fat diet Anxiety-like behavior Microbiota-gut-brain axis 
The effects of 17β-trenbolone and bisphenol A on sexual behavior and social dominance via the hypothalamic-pituitary-gonadal axis in male mice
《Journal of Environmental Sciences》2025年第5期54-67,共14页Xiang Zuo Minghe Sun Huijuan Bai Shuhui Zhang Jialu Luan Qian Yu Zhenhua Fu Qili Zhao Mingzhu Sun Xin Zhao Xizeng Feng 
supported by the National Natural Science Foundation of China(Nos.62027812 and 62273186).
17β-Trenbolone(17-TB)is well documented as an environmental endocrine disruptor in aquatic biological studies,but its effects on mammals remain poorly understood.Furthermore,17-TB acts as a hormone with properties si...
关键词：17β-Trenbolone(17-TB) Bisphenol A(BPA) hypothalamic-pituitary-gonadal axis(HPG) Sex hormones Social dominance Sexual behavior 
Gut microbiota-astrocyte axis: new insights into age-related cognitive decline
《Neural Regeneration Research》2025年第4期990-1008,共19页Lan Zhang Jingge Wei Xilei Liu Dai Li Xiaoqi Pang Fanglian Chen Hailong Cao Ping Lei 
supported by the Haihe Laboratory of Cell Ecosystem Innovation Foundation,No.22HHXBSS00047(to PL);Graduate Science and Technology Innovation Project of Tianjin,No.2022BKY173(to LZ);Tianjin Municipal Science and Technology Bureau Foundation,No.20201194(to PL).
With the rapidly aging human population,age-related cognitive decline and dementia are becoming increasingly prevalent worldwide.Aging is considered the main risk factor for cognitive decline and acts through alterati...
关键词：age aging Alzheimer’s disease ASTROCYTES cognitive decline dementia gut microbiota gut–brain axis microbial metabolites NEUROINFLAMMATION Parkinson’s disease 
Ocular biological characteristics and refractive errors in children with unilateral congenital ptosis
《International Journal of Ophthalmology(English edition)》2025年第4期691-698,共8页Yu-Ying Sun Bing-Ying Lin Zhen Mao Xuan-Wei Liang Cui-Yu Zhang Dan-Ping Huang Yao Ni Zuo-Hong Li 
Supported by the Fundamental Research Funds of the State Key Laboratory of Ophthalmology(No.30306020240020319);Municipal School(Hospital)Jointly Fund Project of Guang Zhou(No.SL2024A03J00492);Teaching Reform Projects in 2023 by the Steering Committee for the Construction of New Medical Departments in Guangdong Province;Guangdong Medical Research Foundation(No.A2021369);Natural Science Foundation of Guangdong Province,China(No.2023A1515011652).
AIM:To evaluate refraction and ocular biological characteristics in children with unilateral congenital ptosis.METHODS:In this cross-sectional study,200 Chinese children(3-15y)with unilateral congenital ptosis were ev...
关键词：congenital ptosis axis length ocular biological characteristics 
Review of the mechanisms of the biliary-enteric axis in the development of cholangiocarcinoma
《World Journal of Clinical Oncology》2025年第4期44-52,共9页Tian-Hao Shen Xue Yu Cheng Zhou Yu Liu Qiu-Ying Li Wei Li Ting-Hui Jiang Yong-Qiang Zhu Yan Liu 
Cholangiocarcinoma(CCA)is a particularly aggressive and challenging type of cancer,known for its poor prognosis,which is worsened by the complex interplay of various biological and environmental factors that contribut...
关键词：CHOLANGIOCARCINOMA Biliary-enteric communication of liver-gut axis MICROBIOME Bile acid metabolism Inflammatory response 
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