Supported by the Ningbo Natural Science Foundation(No.2023J212);Zhejiang Medical and Health Technology Program(No.2023KY1141).
AIM:To investigate the effects of nintedanib on epithelial-mesenchymal transition(EMT)in cells derived from pterygium,aiming to explore its potential as a pharmacological intervention for pterygium treatment.METHODS:P...
supported by the National Key R&D Program of China(2018YFA0800700,2018YFA0800900 and 2023YFA1801100);National Natural Science Foundation of China(32170787,91954108,91857201 and 32100557)。
The lipid droplet(LD)is a conserved organelle that exists in almost all organisms,ranging from bacteria to mammals.Dysfunctions in LDs are linked to a range of human metabolic syndromes.The formation of protein comple...
funded by the National Key R&D Program of China(Grant No.2019YFE0118300);the National Natural Science Foundation of China(Grant Nos.U1804234,31901542,and 31861143008);the Henan Natural Science Foundation,China(Grant No.202300410196)。
As a novel post-translational modification(PTM),lysine 2-hydroxyisobutyrylation(Khib)is considered to regulate gene transcriptional activities in eukaryotic cells;however,the functions of Khib-modified proteins in pla...
Objective: The aim of the present study was to check the potential interaction of two neurodevelopmental proteins, Disc1 and Gas7, in the adult mice brain. Methods: Twenty-four male Swiss albino mice were used for the...
Deletion of HAX1 in mice causes a severe reduction in the numbers of lymphocytes in the bone marrow and in the spleen. Additionally, B220+ B progenitor cells in the bone marrow are reduced, suggesting an important fu...
There is a close relationship between telomeres-telomerase and age-related disease. Human telomerase reverse tran- scriptase (hTERT) is both the catalytic component of human telomerase and the rate-limiting determin...
Supported by National Natural Science Foundation (30972454);Shenzhen Science and Technology Plan Major Project (200801010)~~
[Objective] The aim was to investigate the possible interaction between SET and eEF1A1 in human liver cells. [Method] Firstly the total proteins of human L-02 liver cells were extracted under non-denaturing conditions...
supported by the Scientific and Technological Development Research Project of Shaanxi Province (No.2005k09-G1)
Objective To investigate the interaction between fragile histamine triad (FHIT) and protein kinase C alpha (PKCα) in human non-small cell lung cancer tissues. Methods FHIT and PKCα double positive samples were scree...
The identification of novel biomarkers for early prostate cancer diagnosis is highly important because early detection and treatment are critical for the medical management of patients. Disruption in the continuity of...