CO-IMMUNOPRECIPITATION

作品数:9被引量:27H指数:2
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相关领域:医药卫生生物学更多>>
相关作者:李杰杨细飞杨亮刘建军张毅更多>>
相关机构:深圳市疾病预防控制中心华南理工大学浙江省医学科学院浙江大学更多>>
相关期刊:《Cellular & Molecular Immunology》《International Journal of Ophthalmology(English edition)》《Genomics, Proteomics & Bioinformatics》《Journal of Pharmaceutical Analysis》更多>>
相关基金:国家自然科学基金更多>>
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Nintedanib regulates miR-23b-3p/TGFBR2 axis and competitively binds to TGFBR2 protein, inhibiting EMT process in human pterygium cells
《International Journal of Ophthalmology(English edition)》2025年第5期779-791,共13页Ke-Ke Zhang Meng Li Yan-Hong Liao Xiao-Tian Liu Yong-Bo Bao Yan Gong 
Supported by the Ningbo Natural Science Foundation(No.2023J212);Zhejiang Medical and Health Technology Program(No.2023KY1141).
AIM:To investigate the effects of nintedanib on epithelial-mesenchymal transition(EMT)in cells derived from pterygium,aiming to explore its potential as a pharmacological intervention for pterygium treatment.METHODS:P...
关键词:PTERYGIUM epithelial-mesenchymal transition nintedanib molecular docking CO-IMMUNOPRECIPITATION 
Co-immunoprecipitation for identifying protein-protein interaction on lipid droplets被引量:1
《Biophysics Reports》2024年第2期102-110,共9页Xiaochuan Fu Shuyan Zhang Pingsheng Liu 
supported by the National Key R&D Program of China(2018YFA0800700,2018YFA0800900 and 2023YFA1801100);National Natural Science Foundation of China(32170787,91954108,91857201 and 32100557)。
The lipid droplet(LD)is a conserved organelle that exists in almost all organisms,ranging from bacteria to mammals.Dysfunctions in LDs are linked to a range of human metabolic syndromes.The formation of protein comple...
关键词:Lipid droplet CO-IMMUNOPRECIPITATION Protein interaction 
Global Profiling of 2-hydroxyisobutyrylome in Common Wheat
《Genomics, Proteomics & Bioinformatics》2022年第4期688-701,共14页Ning Zhang Lingran Zhang Linjie Li Junyou Geng Lei Zhao Yan Ren Zhongdong Dong Feng Chen 
funded by the National Key R&D Program of China(Grant No.2019YFE0118300);the National Natural Science Foundation of China(Grant Nos.U1804234,31901542,and 31861143008);the Henan Natural Science Foundation,China(Grant No.202300410196)。
As a novel post-translational modification(PTM),lysine 2-hydroxyisobutyrylation(Khib)is considered to regulate gene transcriptional activities in eukaryotic cells;however,the functions of Khib-modified proteins in pla...
关键词:Post-translational modification Lysine 2-hydroxyisobutyrylation Common wheat PROTEOMICS CO-IMMUNOPRECIPITATION 
Co-immunolocalization of Disc1 and Gas7 protein in adult mice brain
《Brain Science Advances》2022年第1期70-77,共8页Udaya Kumar 
Objective: The aim of the present study was to check the potential interaction of two neurodevelopmental proteins, Disc1 and Gas7, in the adult mice brain. Methods: Twenty-four male Swiss albino mice were used for the...
关键词:Disc1 Gas7 co-immunolocalization co-immuno-fluorescence CO-IMMUNOPRECIPITATION 
HAX1 deletion impairs BCR internalization and leads to delayed BCR-mediated apoptosis被引量:2
《Cellular & Molecular Immunology》2016年第4期451-461,共11页Susanne Wolkerstorfer Elisabeth Schwaiger Mark Rinnerthaler Iris Karina Gratz Thomas Zoegg Hans Brandstetter Gertrude Achatz-Straussberger 
Deletion of HAX1 in mice causes a severe reduction in the numbers of lymphocytes in the bone marrow and in the spleen. Additionally, B220+ B progenitor cells in the bone marrow are reduced, suggesting an important fu...
关键词:VIABILITY apoptosis INTERNALIZATION BCR surface plasmon resonance analysis (SPRA) wild type (WT) B cellreceptor (BCR) co-immunoprecipitation (co-IP) room temperature (RT) annexin V(A) eFluor (eF) 
Effect of newly identified hTERT-interacting proteins on telomerase activity被引量:4
《Acta Biochimica et Biophysica Sinica》2013年第8期674-682,共9页Lina Zhou Bing Chen Xing Hua Ping Zhou Lian Guo Yong Peng Kunhua Qiu 
There is a close relationship between telomeres-telomerase and age-related disease. Human telomerase reverse tran- scriptase (hTERT) is both the catalytic component of human telomerase and the rate-limiting determin...
关键词:TELOMERASE HTERT yeast two-hybrid screen CO-IMMUNOPRECIPITATION 
Verification of the Interaction between SET and eEF1A1 in Human Liver Cells by Co-immunoprecipitation被引量:2
《Agricultural Science & Technology》2010年第8期87-90,共4页杨亮 杨细飞 张毅 刘建军 李杰 
Supported by National Natural Science Foundation (30972454);Shenzhen Science and Technology Plan Major Project (200801010)~~
[Objective] The aim was to investigate the possible interaction between SET and eEF1A1 in human liver cells. [Method] Firstly the total proteins of human L-02 liver cells were extracted under non-denaturing conditions...
关键词:SET eEF1A1 IMMUNOPRECIPITATION INTERACTION 
Interaction between fragile histamine triad and protein kinase C alpha in human non-small cell lung cancer tissues
《Journal of Pharmaceutical Analysis》2009年第1期57-61,共5页Peng-hui Zhuang1, Zhao-hui Liu2, Xiao-gang Jiang3, Cheng-en Pan41. Department of Thoracic Surgery, the First Affiliated Hospital, Medical School of Xi’an Jiaotong University 2. Department of Anatomy and Histology & Embryology, Medical School of Xi’an Jiaotong University 3. Department of Genetics and Molecular Biology, Medical School of Xi’an Jiaotong University 4. Department of Geratic Surgery, the First Affiliated Hospital, Medical School of Xi’an Jiaotong University, Xi’an 710061, China. 
supported by the Scientific and Technological Development Research Project of Shaanxi Province (No.2005k09-G1)
Objective To investigate the interaction between fragile histamine triad (FHIT) and protein kinase C alpha (PKCα) in human non-small cell lung cancer tissues. Methods FHIT and PKCα double positive samples were scree...
关键词:fragile histamine triad (FHIT) protein kinase C alpha (PKCα) non-small cell lung cancer (NSCLC) CO-IMMUNOPRECIPITATION 
Coordinated peak expression of MMP-26 and TIMP-4 in preinvasive human prostate tumor被引量:18
《Cell Research》2006年第9期750-758,共9页Seakwoo Lee Kevin K Desai Kenneth A Iczkowski Robert G Newcomer Kevin J WU Yun-Ge Zhao Winston W Tan Mark D Roycik Qing-Xiang Amy Sang 
The identification of novel biomarkers for early prostate cancer diagnosis is highly important because early detection and treatment are critical for the medical management of patients. Disruption in the continuity of...
关键词:matrix metalloproteinase-26 tissue inhibitor of metalloproteinases-4 high-grade prostatic intraepithel ialneoplasia prostate cancer biomarkers early diagnosis IMMUNOHISTOCHEMISTRY CO-IMMUNOPRECIPITATION 
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