supported by National Institutes of Health(NIH)grant R01CA240447 to W.L.
Melanoma is a lethal skin malignancy and the fifth most diagnosed cancer in the United States.1 Currently,for unresectable melanoma,the recommended treatment options include checkpoint inhibitor immunotherapy targetin...
supported by the National Natural Science Foundation of China(Nos.82272321 and 81971943);Fundamental Research Funds for the Central Universities(2042023kf0230);the Stanley Foundation from the Stanley Medical Research Institute(SMRI),United States(No.06R-1366).
Human endogenous retroviruses(HERVs)are remnants of retroviral infections in human germline cells from millions of years ago.Among these,ERVW-1(also known as HERV-W-ENV,ERVWE1,or ENVW)encodes the envelope protein of t...