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作品数：772被引量：1543H指数：15
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相关机构：中国科学院大学清华大学天津医科大学总医院中国科学院更多>>
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Safety Evaluation of Bridge underMoving Abnormal Indivisible Load Based on Fusing Bridge Inspection Data and Load Test Data
《Structural Durability & Health Monitoring》2025年第3期499-530,共32页He Zhang He-Qing Mu Xiao Zhang He Zhang Yuedong Yang 
funded by the Science and Technology Development Fund(SKLIOTSC(UM)-2021-2023);the State Key Laboratory of Internet of Things for Smart City(University of Macao)(SKL-IoTSC(UM)-2024-2026/ORP/GA07/2023);Guangdong Provincial Key Laboratory of Modern Civil Engineering Technology(2021B1212040003).
Safety evaluation of a bridge under Moving Abnormal Indivisible Loads(MAILs)directly relates to whether an oversized and/or overweight Large-Cargo Transportation(LCT)vehicle is permitted to pass the bridge.Safety eval...
关键词：Moving loads moving abnormal indivisible load large-cargo transportation vehicle load-bearing capacity bridge reliability bridge safety evaluation reliability updating 
The abnormal splicing regulation network caused by synonymous mutations in FBN1 exon 39 leads to Marfan syndrome
《Genes & Diseases》2025年第3期4-6,共3页Fudan Wu Mingjie Li Xuan Zhou Qianyun Wang Yan’an Wu 
supported by the Fujian Provincial Health Technology Project(China)(No.2023QNA016);the Guidance in Medical and Health Program of Xiamen,China(No.3502Z20209120);Scientific Research Foundation for Advanced Talents,Xiang’an Hospital of Xiamen University(China)(No.PM201809170018).
Mutations in fibrillin-1 gene(FBN1)have been shown to be associated with Marfan syndrome and most FBN1 mutations display missense or nonsense.Recently,reports on synonymous mutation-related diseases have attracted wid...
关键词：Marfan syndrome marfan syndrome splicing regulation abnormal splicing synonymous mutation synonymous mutations FBN saccharomyces cerevisiae 
Elevated waist-to-hip ratio,as an abdominal obesity index,predicts the risk of diabetic kidney injury
《World Journal of Diabetes》2025年第4期117-127,共11页Di-Ni Lin Dan Li Meng-Meng Peng Hong Yang Zhen-Zhen Lin En-Ling Ye Wen-Ting Chen Meng-Xue Zhou Xian-En Huang Xue-Mian Lu 
Supported by the Science and Technology Project of Wenzhou City,No.Y20240252 and No.Y2023374.
BACKGROUND Diabetic nephropathy(DN)is associated with a high incidence of type 2 diabetic mellitus(T2DM)in Asia.Central obesity is an important risk factor for DN,represented by a series of indices,including waist cir...
关键词：Diabetic nephropathy Type 2 diabetes mellitus Central obesity Waist-to-hip ratio Abnormal serum lipids 
SET-NUP214-induced hypermethylation landscape promotes abnormal overexpression of HOXC cluster genes in acute megakaryoblastic leukemia
《Genes & Diseases》2025年第2期72-75,共4页Akhilesh Kaushal Samrat Roy Choudhury 
supported by grants from the National Institutes of Health (No.P20GM121293)to S.R.C.;funded by the Seeds of Science Award and startup from the University of Arkansas for Medical Sciences (UAMS) and Arkansas Children's Research Institute (ACRI)to S.R.C.
The SET-NUP214 gene fusion is mainly found in patients primarily diagnosed with T-cell acute lymphoblastic leukemia(T-ALL)and rarely in acute myeloid leukemia(AML).1 Patients with the SET-NUP214 fusion protein(referre...
关键词：acute LEUKEMIA cluster 
Prediction of abnormal TBM disc cutter wear in mixed ground condition using interpretable machine learning with data augmentation
《Journal of Rock Mechanics and Geotechnical Engineering》2025年第4期2059-2071,共13页Kibeom Kwon Hangseok Choi Jaehoon Jung Dongku Kim Young Jin Shin 
support of the“National R&D Project for Smart Construction Technology (Grant No.RS-2020-KA157074)”funded by the Korea Agency for Infrastructure Technology Advancement under the Ministry of Land,Infrastructure and Transport,and managed by the Korea Expressway Corporation.
The widespread adoption of tunnel boring machines(TBMs)has led to an increased focus on disc cutter wear,including both normal and abnormal types,for efficient and safe TBM excavation.However,abnormal wear has yet to ...
关键词：Disc cutter Abnormal wear Mixed ground Interpretable machine learning Data augmentation 
Focal cortical dysplasia type Ⅱ:review of neuropathological manifestations and pathogenetic mechanisms
《Acta Epileptologica》2025年第1期32-44,共13页Yubao Fang Yaqian Zhang Tiancai Huang Shengyu Yang Yinchao Li Liemin Zhou 
supported by the Shenzhen Municipal Science and Technology key projects of the Basic Research Program(file no.LMZ JCYJ20220818102007015);the National Natural Science Foundation of China(file no.LMZ 82071447,82371456).
Focal cortical dysplasia(FCD)is an important cause of intractable epilepsy,with FCD type Ⅱ(FCD Ⅱ)being the most common subtype.FCD Ⅱ is characterized by cortical dyslamination accompanied by dysmorphic neurons(DNs)...
关键词：Focal cortical dysplasia Abnormal differentiation Gene mutations Epigenetic alterations 
Selection of abnormal trends in nuclearβ-decay half-lives by neural network and exploration of the physical mechanisms
《Nuclear Science and Techniques》2025年第3期134-145,共12页Peng Li Zhong-Ming Niu Yi-Fei Niu 
supported by the‘Young Scientist Scheme’of the National Key R&D Program of China(No.2021YFA1601500);National Natural Science Foundation of China(Nos.12075104,12375109,11875070,and 11935001);Anhui Project(Z010118169);Key Research Foundation of the Education Ministry of Anhui Province(No.2023AH050095)。
Nuclearβ-decay,a typical decay process for unstable nuclei,is a key mechanism for producing heavy elements in the Universe.In this study,neural networks were employed to predictβ-decay half-lives and,for the first t...
关键词：β-decay half-lives Neural network Abnormal nuclei 
Serum homocysteine showed potential association with cognition and abnormal gut microbiome in major depressive disorder
《World Journal of Psychiatry》2025年第3期234-248,共15页Chen-Chen Xu Wen-Xuan Zhao Yu Sheng Ya-Jun Yun Ting Ma Ning Fan Jia-Qi Song Jun Wang Qi Zhang 
Supported by the Wuxi Municipal Health Commission Youth Fund Project,No.Q202268;Wuxi Scientific and technological breakthrough of“Light of the Taihu Lake”(Basic Research),No.K20221039;Jiangsu Shuangchuang Doctoral Program,No.JSSCBS20221991;Beijing Municipal Administration of Hospital Incubating Program,No.PX2023070 and No.PX2024072;Capital’s Funds for Health Improvement and Research,No.SF2024-4-2134;Beijing Hospitals Authority Youth Program,No.QML20232003;the Top Talent Support Program for young and middle-aged people of Wuxi Health Committee,No.HB2023089.
BACKGROUND Cognitive impairment is one of the common clinical manifestations of depression,causing negative distress to patients.Elevated homocysteine(Hcy)concentrations and gut microbiome dysfunction may be observed ...
关键词：HOMOCYSTEINE MICROBIOME Intestinal flora Gut microbiota Gut-brain axis Major depressive disorder Cognitive function Cognitive impairment 
Abnormal invasive hemodynamics in heart transplant recipients:A single-center,retrospective study
《World Journal of Transplantation》2025年第3期148-156,共9页Navin Rajagopalan Donna R Dennis Julia Akhtarekhavari Kenneth Campbell 
BACKGROUND Few studies have quantified invasive hemodynamic parameters in post heart transplant recipients.AIM To report the incidence of abnormal hemodynamics in heart transplant recipients at 1-year and 3-year post-...
关键词：Heart transplantation Right heart catheterization OBESITY Heart failure HEMODYNAMICS 
Ambulatory Blood Pressure Characteristics and Risk Factors for Circadian Rhythm Abnormalities in Elderly Patients with Hypertension
《Journal of Clinical and Nursing Research》2025年第3期154-160,共7页Yaqian Huang 
Objective:To analyze the characteristics of ambulatory blood pressure in elderly patients with hypertension and find out the risk factors of abnormal circadian rhythm.Methods:According to the circadian rhythm of patie...
关键词：Elderly patients HYPERTENSION Ambulatory blood pressure Abnormal circadian rhythm 
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