supported by the National Natural Science Foundation of China(31670050,31100069);the Fundamental Research Funds for the Central Universities(XDJK2017B011)。
Dear Editor,Polyene macrolides are a group of natural products with potent antifungal activity (Caffrey et al., 2016). Candicidin/FR-008, a potent broad-spectrum anti-fungal agent, is produced by several Streptomycete...
supported by grants from the Ministry of Science and Technology of China (2015CB150600);the National Natural Science Foundation of China (31571281 and 31771378)
Dear Editor,Streptomyces can produce a large variety of secondary metabolites as a major source of anti-infective, antitumor or immune-suppressive agents widely applied in clinical treatment. Antibiotics-resistant bac...
supported by grants from the National Natural Science Foundation of China(21661140002 and 31470157);the Ministry of Science and Technology of China(2012CB721005 and 2012AA022107)
An ideal surrogate host for heterologous production of various natural products is expected to have efficient nutrient utilization,fast growth,abundant precursors and energy supply,and a pronounced gene expression.Str...