supported by the National Key R&D Program of China(grant number 2019YFA09005400);the Zhejiang Provincial Natural Science Foundation of China(grant number LQ21C010002).
The anti-Clostridium difficile infection(CDI)drug fidaxomicin is a natural polyketide metabolite mainly produced by Micromonosporaceae,such as Actinoplanes deccanensis,Dactylosporangium aurantiacum,and Micromonospora ...
the National Natural Science Foundation of China(32061143035,32271752);Inner Mongolia Seed Industry Science and Technology Innovation Major Demonstration Project(2022JBGS0040);the Fundamental Research Funds for the Central Universities(lzujbky-2022-ey17).
The plant natural product scopolin,a coumarin secondary metabolite,has been extensively exploited in flavor,cosmetic,medicine,and other industrial fields.Melilotus albus,a leguminous rotation crop,contains high concen...
supported by the National Key R&D Program of China(grant number 2018YFA0900400);the National Natural Science Foundation of China(grant number 32100053).
Metabolomics is an essential discipline in omics technology that promotes research on the biology of microbial systems.Streptomyces albus J1074 is a model organism used in fundamental research and industrial microbiol...
This work was supported by the National Key R&D Program of China[grant number 2018YFA0900400];the National Natural Science Foundation of China[grant number 31670090],and J1 Biotech Co.,Ltd.
Spinosyns are natural broad-spectrum biological insecticides with a double glycosylated polyketide structure that are produced by aerobic fermentation of the actinomycete,Saccharopolyspora spinosa.However,their large-...
supported by grants from National Key Research and Development Program of China(2018YFC1200100 and 2020YFC0842400);Guangdong Medical Science and Technology Research Center Project(A2019460);Entrepreneurship Leadership Project in Guangzhou Development Zone of China(CY2018-003);Guangzhou Science and Technology Project(202008040002);Scientific Research Project of Guangdong Province Traditional Chinese Medicine Bureau(20201191);Innovative and Strong School Project of Guangdong Provincial Department of Education(2020KZDZX1122);Guangdong Science and Technology Project(2020B111106001);Foshan Science and Technology Innovation Project(2020001000416).
The incidences of nosocomial infections(NIs)are increasing throughout the world,especially for those airborne diseases caused by pathogens or air particulates that float in air.In this study,we designed and manufactur...
supported by the National Natural Science Foundation of China(31670050,31100069);the Fundamental Research Funds for the Central Universities(XDJK2017B011)。
Dear Editor,Polyene macrolides are a group of natural products with potent antifungal activity (Caffrey et al., 2016). Candicidin/FR-008, a potent broad-spectrum anti-fungal agent, is produced by several Streptomycete...
Supported by Hunan Science and Technology Department Planning Project(2012NK3056)
[Objectives]The effect and mechanism of grape seed and sweet wormwood extract on growth of Monopterus albus were studied.[Methods]1 500 healthy M.albus with average mass of 23.8 g/tail were randomly divided into 5 gro...
supported by grants from the Ministry of Science and Technology of China (2015CB150600);the National Natural Science Foundation of China (31571281 and 31771378)
Dear Editor,Streptomyces can produce a large variety of secondary metabolites as a major source of anti-infective, antitumor or immune-suppressive agents widely applied in clinical treatment. Antibiotics-resistant bac...