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Active Components Formulation Developed from Fuzheng Huayu Recipe for Anti-Liver Fibrosis被引量：3
《Chinese Journal of Integrative Medicine》2022年第6期538-544,共7页SUN Xin TAN Ye LYU Jing LIU Hong-liang ZHAO Zhi-min LIU Cheng-hai 
Supported by the Major Projects of the Ministry of Science and Technology of China(No.2014ZX10005001);the National Natural Science Foundation of China(No.81603467,81730109);the Third Batch of Open Projects of Shanghai Innovation Center of Traditional Chinese Medicine Health Service(No.ZYJKFW201811013)。
Objective:To screen the active components from Fuzheng Huayu Recipe(FZHY)and redesign a new recipe composed of the active components,and validate the effect of active components formulation from FZHY against liver fib...
关键词：active components formulation Fuzheng Huayu Recipe Chinese medicine liver fibrosis hepatic stellate cells hepatic sinusoidal capillarization 
Structural basis for recognition of anti-migraine drug lasmiditan by the serotonin receptor 5-HT1F-G protein complex被引量：4
《Cell Research》2021年第9期1036-1038,共3页Sijie Huang Peiyu Xu Yangxia Tan Chongzhao You Yumu Zhang Yi Jiang H.Eric Xu 
This work vyas partially supported by the Ministry of Science and Technology of China(2018YFA0507002 to HEX);Strategic Priority Research Program of the Chinese Academy of Sciences(XDB37030103 to HEX);Shanghai Municipal Science and Technology Major Project(2019SHZDZX02 to HEX);the National Natural Science Foundation of China(31770796 to YJ);National Science&Technology Major Project"Key New Drug Creation and Manufacturing Program"(2018ZX09711002-002-002 to YJ).
Dear Editor,The serotonin 5-HTt receptor subtypes,including 5-HT_(1A)/5-HT_(1B)/5-HT_(1D),5-HT_(1E),and 5-HT_(1F),are G protein-coupled receptors(GPCRs)that respond to the endogenous neurotransmitter serotonin and cou...
关键词：SEROTONIN ENDOGENOUS MIGRAINE 
Adjuvant therapies after curative treatments for hepatocellular carcinoma: Current status and prospects被引量：14
《Genes & Diseases》2020年第3期359-369,共11页Xiao-Dong Zhu Kang-Shuai Li Hui-Chuan Sun 
This work was supported by the Leading Investigator Program of Shanghai municipal government(17XD1401100);the National Key Basic Research Program(973 Program,2015CB554005)from the Ministry of Science and Technology of the People’s Republic of China;the National Natural Science Foundation of China(81372655,81472224 and 81672326)to HCS.
Tumor recurrence rate after surgery or ablation of hepatocellular carcinoma(HCC)is as high as 70%.However,there are no widely accepted adjuvant therapies;therefore,no treatment has been recommended by guidelines from ...
关键词：Adjuvant therapy Anti-PD-1 antibody Clinical trial Hepatocellular carcinoma Molecular targeted therapy Recurrence-free survival 
Intracellular codelivery of anti-inflammatory drug and anti-miR 155 to treat inflammatory disease被引量：14
《Acta Pharmaceutica Sinica B》2020年第8期1521-1533,共13页Chao Teng Chenshi Lin Feifei Huang Xuyang Xing Shenyu Chen Ling Ye Helena S.Azevedo Chenjie Xu Zhengfeng Wu Zhongjian Chen Wei He 
supported by the National Natural Science Foundation of China(Nos.81872823 and 81773826);the Double First-Class(CPU2018PZQ13,China)of the China Pharmeutical University;the Ministry of Science and Technology of China(2018ZX09711001);the Shanghai Science and Technology Committee(19430741500,China);the Key Laboratory of Modern Chinese Medicine Preparation of Ministry of Education of Jiangxi University of traditional Chinese Medicine(TCM201905,China)
Atherosclerosis(AS) is a lipid-driven chronic inflammatory disease occurring at the arterial subendothelial space. Macrophages play a critical role in the initiation and development of AS. Herein,targeted codelivery o...
关键词：miR155 INFLAMMATORY SUSTAINED 
Plant-derived phosphocholine facilitates cellular uptake of anti-pulmonary fibrotic HJT-sRNA-m7被引量：37
《Science China(Life Sciences)》2019年第3期309-320,共12页Jianchao Du Zhu Liang Jiantao Xu Yan Zhao Xiaoyun Li Yanli Zhang DANDan Zhao Ruxuan Chen Yang Liu Trupti Joshi Jiahui Chang Zhiqing Wang Yanxu Zhang Jindong Zhu Qiang Liu Dong Xu Chengyu Jiang 
supported by the Ministry of Science and Technology of China (2015CB553406);the National Natural Science Foundation of China (81230002, 81490531);the Ministry of Education (IRT1121, B08007)
Pulmonary fibrosis, a progressive chronic disease with a high mortality rate, has limited treatment options. Currently, lung transplantation remains the only effective treatment. Here we report that a small RNA, HJT-s...
关键词：PC CELLULAR UPTAKE anti-fibrotic HJT SRNA 
Demonstration of quantum anti-Zeno effect with a single trapped ion
《Chinese Physics B》2018年第9期191-196,共6页Man-Chao Zhang Wei Wu Lin-Ze He Yi Xie Chun-Wang Wu Quan Li Ping-Xing Chen 
Project supported by the National Basic Research Program of China(Grant No.2016YFA0301903);the National Natural Science Foundation of China(Grant Nos.11174370,11304387,61632021,11305262,11574398,and N 61205108);the Research Plan Project of National University of Defense Technology,China(Grant No.ZK16-03-04)
We experimentally demonstrate the quantum anti-Zeno effect in a two-level system based on a single trapped ion ^（40）Ca~＋. In the large detuning regime, we show that the transfer from the ground state to the excited...
关键词：quantum anti-Zeno effect single trapped ion quantum measurement 
Observation of Weak Anti-Localization and Electron-Electron Interaction on Few-Layer 1T′-MoTe2 Thin Films
《Chinese Physics Letters》2018年第7期95-98,共4页王钦 于鹏 黄祥威 樊洁 景秀年 姬忠庆 刘政 刘广同 杨昌黎 吕力 
Supported by the National Basic Research Program of China under Grant Nos 2014CB920904 and 2015CB921101;the Strategic Priority Research Program B of the Chinese Academy of Sciences under Grant No XDB07010200;the Singapore National Research Foundation under Grant No NRF-RF2013-08
Electronic transports of few-layer 1T＇-MoTe2 films are measured at temperatures down to 0.26 K. The lowtemperature conductivity exhibits logarithmic temperature dependence and negative magneto response. The negative ...
Mechanically robust antireflective coatings
《Nano Research》2018年第3期1699-1713,共15页Sadaf Bashir Khan Hui Wu Xiaochen Huai Sumeng Zou Yuehua Liu Zhengjun Zhang 
The authors are grateful to the financial support by the National Basic Research Program of China （973 program, No. 2013CB934301）, the National Natural Science Foundation of China （Nos. 51531006 and 51572148）, the Research Project of Chinese Ministry of Education （No. 113007A）, and the Tsinghua University Initiative Scientific Research Program.
Mechanical strength is an essential parameter that influences and limits the lifetime performance of antireflective （AR） coatings in optical devices. Speciflcally, amphiphobic AR coatings with reduced reflectance ar...
关键词：antireflection （AR） super-liquid repellency thin films thermally stable mechanically robust ADHESION 
Interaction between anti-shear galleries and surrounding rock in the right-bank slope of Dagangshan hydropower station被引量：2
《Journal of Mountain Science》2017年第7期1428-1444,共17页LI Lian-chong XING Ya-zi LIU Xing-zong MA Ke XU Nu-wen ZHANG Fei 
jointly supported by grants from the National Key Research and Development Program(Grant No.2016YFC0801607,2016YFC0801602);the National Natural Science Foundation of China(Grant No.51279024);the National Basic Research Program of China(Grant No.2014CB047103)
The fight-bank slope of the Dagangshan hydropower station located in Southwest China is a highly unloaded rock slope. Moreover, large-scale natural faults were detected in the slope body; some excavation-induced unloa...
关键词：Slope stability Microseismic monitoring Numerical simulation Safety factor Anti-sheargallery 
Weak Anti-Localization and Quantum Oscillations in Topological Crystalline Insulator PbTe
《Chinese Physics Letters》2017年第2期67-70,共4页Ke-Jie Wang Wei Wang Min-Hao Zhang Xiao-Qian Zhang Pei Yang Bo Liu Ming Gao Da-Wei Huang Jun-Ran Zhang Yu-Jie Liu Xue-Feng Wang Feng-Qiu Wang Liang He Yong-Bing Xu Rong Zhang 
Supported by the National Key Research and Development Program of China under Grant No 2016YFA0300803;the National Basic Research Program of China under Grant No 2014CB921101;the National Natural Science Foundation of China under Grant Nos 61474061 and 61674079
Topological crystalline insulators （TCIs） have attracted worldwide interest since their theoretical predication and have created exciting opportunities for studying topological quantum physics and for exploring spin...
关键词：Weak Anti-Localization and Quantum Oscillations in Topological Crystalline Insulator PbTe length 
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