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作品数：2030被引量：3606H指数：21
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Treatment of immunoglobulin A nephropathy:Current perspective and future prospects
《World Journal of Clinical Cases》2025年第19期5-10,共6页Yusuf ZiyaŞener SeherŞener 
Immunoglobulin(Ig)A nephropathy is the most common type of primary glomerulonephritis globally.It typically manifests with microscopic hematuria and a spectrum of proteinuria,although rapidly progressive glomeruloneph...
关键词：Immunoglobulin A nephropathy Telitacicept Complement inhibitors B-cell lineage depletion Anti-proteinuric treatment 
Novel silver nanoparticles loaded Cu-based metal-organic framework as a promising antimicrobial material for controlling Escherichia coli O157:H7 in pork
《Food Science and Human Wellness》2025年第3期914-924,共11页Dongbo Yang Jing Yi Xiaoya Li Shuqi Zhang Yiming Xiang Xingxing Liu Zhongguo Shan Haihua Wang 
funded by the Key Research and Development Projects of Shaanxi Province(2023-YBNY-178);Shaanxi Fundamental Science Research Project for Chemistry&Biology(22JHQ029);China Postdoctoral Science Foundation(2019M653766);National Natural Science Foundation of China(21901212)。
The risk of infection following consumption of foodborne pathogens contaminated foods became a significant concern for human health and imposes great economic losses to food industry.Herein,Ag nanoparticles were integ...
关键词：Metal-organic frameworks ANTIMICROBIAL ANTIBIOFILM Pork model 
Unsaponifiable matter from walnut oil ameliorate memory deficits and mitochondrial dysfunction in aging mice via activating Nrf2 signaling pathway
《Food Science and Human Wellness》2025年第3期1127-1138,共12页Dan Hong Xiao Xiao Aijin Ma Zhou Chen Siting Li Junxia Xia Yiling Tian Yingmin Jia 
supported by the National Key Research and Development Program(2022YFD1600402);Hebei Provincial Major Science and Technology Achievement Transformation Project(21287101Z);Hebei Provincial Innovation and Entrepreneurship Team Project(215A7102D)。
Aging is an inevitable biological phenomenon that involves a multitude of physiological alterations.Dietary interventions are being considered as potential strategies for delaying age-related dysfunction.Unsaponifiabl...
关键词：Unsaponifiable matter Memory impairment mitochondrial dysfunctions Nrf2 signaling pathway Antioxidant stress 
Granulomatosis with polyangiitis induced by the anti-programmed cell death-1 inhibitor tislelizumab:A case report
《World Journal of Clinical Cases》2025年第15期56-62,共7页Jian-Hui Zhao Jing-Jiao Wang Yi-Wen Li 
BACKGROUND Immune checkpoint inhibitors(ICIs)are a new class of antitumor agents.They enhance antitumor effects by blocking inhibitory receptors and related ligands expressed on T cells.ICIs also modulate regular immu...
关键词：Tislelizumab Programmed cell death-1 inhibitor Granulomatosis with polyangiitis Anti-neutrophil cytoplasmic antibody-associated vasculitis Case report 
An Uncertainty Quantization-Based Method for Anti-UAV Detection in Infrared Images
《Computers, Materials & Continua》2025年第4期1439-1458,共20页Can Wu Wenyi Tang Yunbo Rao Yinjie Chen Hui Ding Shuzhen Zhu Yuanyuan Wang 
supported by the Science and Technology Project of Sichuan(Grant No.2024ZHCG0170);the National Key Research and Development Program of China,“Key Technologies for Instrumentation and Control System Program Security Based on Blockchain”(Project No.2024YFB3311000);States Key Laboratory of Air Traffic Management System(Grant No.SKLATM202202);the Chengdu Science and Technology Project(Grant No.2022-YF05-00068-SN).
Infrared unmanned aerial vehicle(UAV)target detection presents significant challenges due to the inter-play between small targets and complex backgrounds.Traditional methods,while effective in controlled environments,...
关键词：Object segmentation uncertainty quantification bayesian convolutional neural network 
Identification of key hub genes associated with anti-gastric cancer effects of lotus plumule based on machine learning algorithms
《World Journal of Gastrointestinal Oncology》2025年第4期384-415,共32页Fan-Di Meng Shu-Min Jia Yu-Bin Ma Yu-Hua Du Wen-Jing Liu Yi Yang Ling Yuan Yi Nan 
Supported by Ningxia Key Research and Development Program,No.2023BEG02015;Talent Development Projects of Young Qihuang of National Administration of Traditional Chinese Medicine(2020).
BACKGROUND Lotus plumule and its active components have demonstrated inhibitory effects on gastric cancer(GC).However,the molecular mechanism of lotus plumule against GC remains unclear and requires further investigat...
关键词：Gastric cancer Lotus plumule Network pharmacology Weighted gene co-expression network analysis Machine learning 
Structurally diverse sesquiterpenoids with anti-MDR cancer activity from Penicillium roqueforti
《Chinese Journal of Natural Medicines》2025年第4期504-512,共9页Shuyuan Mo Nanjin Ding Zhihong Huang Jun Yao Weiguang Sun Jianping Wang Yonghui Zhang Zhengxi Hu 
supported by the National Natural Science Foundation of China(Nos.82273811,32470417,and U22A20380);the National Program for Support of Top-notch Young Professionals(No.0106514050);the Hubei Provincial Natural Science Foundationof China(No.2024AFA028);the National Key R&D Program of China(No.2021YFA0910500);the Science and Technology Major Project of Hubei Province(Nos.2021ACA012 and 2024BCB021);the Chinese Medicine Research Foundation of the Health Commission of Hubei Province(No.ZY2025Z013)。
Five novel nor-eremophilane-type sesquiterpenoids,peniroqueforins E–H and J(1–4 and 7),two new eremophilane-type sesquiterpenoids,peniroqueforins I and K(5 and 8),and a new eudesmane-type sesquiterpenoid,peniroquefo...
关键词：Penicillium roqueforti SESQUITERPENOIDS Nor-sesquiterpenoids Anti-MDR cancer activity 
Anti-nuclear cytoplasmic antibody-associated vasculitis and kidney cancer:A mini review
《World Journal of Nephrology》2025年第2期27-33,共7页Samuel Wilding Henry H L Wu Nina Brown Rajkumar Chinnadurai 
This mini review explores the links between anti-neutrophil cytoplasmic antibody-associated vasculitis(AAV)and kidney cancer.Several studies suggest an increased incidence of cancer for patients with AAV.Different can...
关键词：Anti-nuclear cytoplasmic antibody-associated vasculitis Kidney cancer Etiology Pathophysiology Immunosuppression 
Therapeutic targeting of cellular prion protein: toward the development of dual mechanism anti-prion compounds
《Neural Regeneration Research》2025年第4期1009-1014,共6页Antonio Masone Chiara Zucchelli Enrico Caruso Giovanna Musco Roberto Chiesa 
supported by Telethon Italy award GGP15225(to RC and GM);Italian Ministry of Health award RF-2016-02362950(to RC and CZ);the CJD Foundation USA(to RC);the Associazione Italiana Encefalopatie da Prioni(AIEnP)(to RC).
PrPSc,a misfolded,aggregation-prone isoform of the cellular prion protein(PrPC),is the infectious prion agent responsible for fatal neurodegenerative diseases of humans and other mammals.PrPSccan adopt different patho...
关键词：anti-prion drug anti-PrPC antibody antisense oligonucleotide NEURODEGENERATION pharmacological chaperone porphyrin prion disease PrPC degrader PrPC shedding zinc finger repressor 
Bacteriocin Microcin J25’s antibacterial infection effects and novel non-microbial regulatory mechanisms: differential regulation of dopaminergic receptors
《Journal of Animal Science and Biotechnology》2025年第2期813-830,共18页Lijun Shang Fengjuan Yang Qingyun Chen Ziqi Dai Guangxin Yang Xiangfang Zeng Shiyan Qiao Haitao Yu 
supported by the National Key Research and Development Program of China(Grant number 32030105);National Pig Technology Innovation Center Leading Technology Projects(NCTIP XD/B05);Beijing Innovation Consortium of Livestock Research System(BAIC05-2024).
Background The antibacterial and immunomodulatory activities of bacteriocins make them attractive targets for development as anti-infective drugs.Although the importance of the enteric nervous system(ENS)in the strugg...
关键词：Arachidonic acid Dopaminergic receptors Enteric nervous system MACROPHAGE MICROBIOTA Microcins 
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