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Treatment of immunoglobulin A nephropathy:Current perspective and future prospects
《World Journal of Clinical Cases》2025年第19期5-10,共6页Yusuf ZiyaŞener SeherŞener 
Immunoglobulin(Ig)A nephropathy is the most common type of primary glomerulonephritis globally.It typically manifests with microscopic hematuria and a spectrum of proteinuria,although rapidly progressive glomeruloneph...
关键词：Immunoglobulin A nephropathy Telitacicept Complement inhibitors B-cell lineage depletion Anti-proteinuric treatment 
Novel silver nanoparticles loaded Cu-based metal-organic framework as a promising antimicrobial material for controlling Escherichia coli O157:H7 in pork
《Food Science and Human Wellness》2025年第3期914-924,共11页Dongbo Yang Jing Yi Xiaoya Li Shuqi Zhang Yiming Xiang Xingxing Liu Zhongguo Shan Haihua Wang 
funded by the Key Research and Development Projects of Shaanxi Province(2023-YBNY-178);Shaanxi Fundamental Science Research Project for Chemistry&Biology(22JHQ029);China Postdoctoral Science Foundation(2019M653766);National Natural Science Foundation of China(21901212)。
The risk of infection following consumption of foodborne pathogens contaminated foods became a significant concern for human health and imposes great economic losses to food industry.Herein,Ag nanoparticles were integ...
关键词：Metal-organic frameworks ANTIMICROBIAL ANTIBIOFILM Pork model 
Unsaponifiable matter from walnut oil ameliorate memory deficits and mitochondrial dysfunction in aging mice via activating Nrf2 signaling pathway
《Food Science and Human Wellness》2025年第3期1127-1138,共12页Dan Hong Xiao Xiao Aijin Ma Zhou Chen Siting Li Junxia Xia Yiling Tian Yingmin Jia 
supported by the National Key Research and Development Program(2022YFD1600402);Hebei Provincial Major Science and Technology Achievement Transformation Project(21287101Z);Hebei Provincial Innovation and Entrepreneurship Team Project(215A7102D)。
Aging is an inevitable biological phenomenon that involves a multitude of physiological alterations.Dietary interventions are being considered as potential strategies for delaying age-related dysfunction.Unsaponifiabl...
关键词：Unsaponifiable matter Memory impairment mitochondrial dysfunctions Nrf2 signaling pathway Antioxidant stress 
Granulomatosis with polyangiitis induced by the anti-programmed cell death-1 inhibitor tislelizumab:A case report
《World Journal of Clinical Cases》2025年第15期56-62,共7页Jian-Hui Zhao Jing-Jiao Wang Yi-Wen Li 
BACKGROUND Immune checkpoint inhibitors(ICIs)are a new class of antitumor agents.They enhance antitumor effects by blocking inhibitory receptors and related ligands expressed on T cells.ICIs also modulate regular immu...
关键词：Tislelizumab Programmed cell death-1 inhibitor Granulomatosis with polyangiitis Anti-neutrophil cytoplasmic antibody-associated vasculitis Case report 
Therapeutic targeting of cellular prion protein: toward the development of dual mechanism anti-prion compounds
《Neural Regeneration Research》2025年第4期1009-1014,共6页Antonio Masone Chiara Zucchelli Enrico Caruso Giovanna Musco Roberto Chiesa 
supported by Telethon Italy award GGP15225(to RC and GM);Italian Ministry of Health award RF-2016-02362950(to RC and CZ);the CJD Foundation USA(to RC);the Associazione Italiana Encefalopatie da Prioni(AIEnP)(to RC).
PrPSc,a misfolded,aggregation-prone isoform of the cellular prion protein(PrPC),is the infectious prion agent responsible for fatal neurodegenerative diseases of humans and other mammals.PrPSccan adopt different patho...
关键词：anti-prion drug anti-PrPC antibody antisense oligonucleotide NEURODEGENERATION pharmacological chaperone porphyrin prion disease PrPC degrader PrPC shedding zinc finger repressor 
Anti-Swelling Polyelectrolyte Hydrogel with Submillimeter Lateral Confinement for Osmotic Energy Conversion
《Nano-Micro Letters》2025年第4期96-110,共15页Yongxu Liu Jiangnan Song Zhen Liu Jialin Chen Dejuan Wang Hui Zhi Jiebin Tang Yafang Zhang Ningbo Li Weijia Zhou Meng An Hong Liu Guobin Xue 
supported by The Project of“20 Items of University”of Jinan(Grant No.202228078);Innovative Research Team in Higher Educational Institutions of Shandong Province(Grant No.2023KJ107);Taishan Scholars Program of Shandong Province(tsqn201812085);National Natural Science Foundation of China(Grant No.51903102,Grant No.52376063,Grant No.52302256);China Postdoctoral Science Foundation(Grant No.2023MD744223).
Harvesting the immense and renewable osmotic energy with reverse electrodialysis(RED)technology shows great promise in dealing with the ever-growing energy crisis.One key challenge is to improve the output power densi...
关键词：Ionic polymer HYDROGEL Confinement effect Anti-swelling Osmotic energy conversion 
Overall survival with frontline vs subsequent anti-epidermal growth factor receptor therapies in unresectable,RAS/BRAF wild-type,leftsided metastatic colorectal cancer
《World Journal of Clinical Oncology》2025年第3期57-67,共11页Nussara Pakvisal Richard M Goldberg Chirawadee Sathitruangsak Witthaya Silaphong Satawat Faengmon Nattaya Teeyapun Chinachote Teerapakpinyo Suebpong Tanasanvimon 
BACKGROUND The combination of anti-epidermal growth factor receptor(EGFR)therapy and chemotherapy is currently a preferred first-line treatment for patients with unre-sectable,RAS and BRAF wild-type,left-sided metasta...
关键词：Metastatic colorectal cancer Anti-epidermal growth factor receptor FRONTLINE Subsequent line RAS wild-type metastatic colorectal cancer BRAF wild-type metastatic colorectal cancer Left-sided metastatic colorectal cancer Overall survival 
Two Years of Modified Protocol with Cyclosporin A for Treatment of Acute Insulin Resistance Induced by Anti-Glutamic Acid Decarboxylase (GAD) Antibodies in Obese Type II Diabetics
《Journal of Diabetes Mellitus》2025年第1期52-58,共7页Kamel El-Reshaid Shaikha Al-Bader 
Background: Diabetes mellitus (DM) is a disease characterized by hyperglycemia due to (a) insulin-insufficiency (type I DM), or (b) impaired glucose cell-entry (insulin resistance) due to the downregulation of insulin...
关键词：Anti-GAD Antibodies C-PEPTIDE Cyclosporin A Diabetes Mellitus HYPERGLYCEMIA Insulin Resistance Therapy 
Flexible dual-Janus porous membrane for underwater gas bubbles anti-buoyancy unidirectional transportation
《Science China Chemistry》2025年第3期881-890,共10页Shuang Ben Han Ma Rui Liu Yuzhen Ning Zhihong Zhao Xudong Zhang Qiang Li Kesong Liu 
supported by the National Natural Science Foundation of China (22105014,21871020,52303143);the China Postdoctoral Science Foundation (2020M680296,2022T150035,2021TQ0023);the High-level Talent Project of Shenyang Ligong University;the Special fund of Basic Scientific Research Expenses for Undergraduate Universities in Liaoning Province (LJ212410144077,LJ212410144072);the Beijing Young Talent Support Program;the 111 Project;the Fundamental Research Funds for the Central Universities。
Controllable transportation of bubbles in surfactant or aqueous is very important in daily chemical products,food fermentation,mineral flotation and other fields.However,bubbles are mainly dominated by buoyancy and mo...
关键词：air diode anti-buoyancy unidirectional penetration without additional force dual-Janus membranes wettability gradient structural gradient 
Designing carboxymethyl cellulose based hydrogel electrolyte membranes enhanced by inorganic nanoparticle toward stable zinc anode
《Green Energy & Environment》2025年第3期537-550,共14页Xiangye Li Yuan Li Yu Jiang Dahui Wang Fen Ran 
supported by the National Natural Science Foundation of China (51763014 and 52073133);Key Talent Project Foundation of Gansu Province;Joint fund between Shenyang National Laboratory for Materials Science and State Key Laboratory of Advanced Processing and Recycling of Nonferrous Metals (18LHPY002);the Program for Hong Liu Distinguished Young Scholars in Lanzhou University of Technology。
Aqueous zinc metal batteries have garnered substantial attention ascribing to affordability,intrinsic safety,and environmental benignity Nevertheless,zinc metal batteries yet are challenged with potential service life...
关键词：Carboxymethyl cellulose Graphite oxide Hydrogel electrolyte Anti-swelling 
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