ANTI-HCV

作品数:39被引量:75H指数:6
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相关领域:医药卫生更多>>
相关作者:徐万洲谢云峥朱绍文祝宏贾海英更多>>
相关机构:广东国际旅行卫生保健中心第二军医大学武汉大学浙江省血液中心更多>>
相关期刊:《传染病信息》《Journal of Pharmaceutical Analysis》《Journal of Life Sciences》《中华实验和临床感染病杂志(电子版)》更多>>
相关基金:国家自然科学基金国家高技术研究发展计划北京市自然科学基金北京大学人民医院研究与发展基金更多>>
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化学发光法检测Anti-HCV在临床中的应用价值分析
《中文科技期刊数据库(引文版)医药卫生》2023年第5期88-90,共3页赵红梅 
研究分析化学发光法对人抗丙型肝炎病毒抗体(Human Hepatitis C virus antibodies,Anti-HCV)检测的临床应用价值。方法:随机选取我院2021年1月至2022年12月的30例丙型肝炎患者,将其视为本研究观察对象,对其采取时间分辨荧光免疫法、化...
关键词:化学发光法 时间分辨荧光免疫法 ANTI-HCV 临床应用价值 
Role of Ras-related Nuclear Protein/Polypyrimidine Tract Binding Protein in Facilitating the Replication of Hepatitis C Virus
《Journal of Clinical and Translational Hepatology》2021年第4期458-465,共8页Jihua Xue Jun Cheng Xuejiao Ma Yixian Shi Huafa Yin Yufeng Gao Jiabin Li 
The work was supported by the Anhui Provincial Natural Science Foundation(1608085QH172);States S&T Projects of 13th Five Year(2018ZX10302206),Chinese Founda-tion for Hepatitis Prevention and Control(TQGB20200151,TQGB20180367);Anhui Key Program of Medical Scien-tific Research of China(#2010A010).
Background and Aims:Ras-related nuclear(RAN)protein is a small GTP-binding protein that is indispensable for the translocation of RNA and proteins through the nuclear pore complex.Recent studies have indicated that RA...
关键词:Ras-related nuclear protein HCV infection Polypyrimidine tractbinding protein Nucleo-cytoplasmic translocation Novel anti-HCV therapeutics 
Structural basis for the inhibition of the SARS-CoV-2 main protease by the anti-HCV drug narlaprevir被引量:1
《Signal Transduction and Targeted Therapy》2021年第3期584-586,共3页Yu Bai Fei Ye Yong Feng Hanyi Liao Hao Song Jianxun Qi George Fu Gao Wenjie Tan Lifeng Fu Yi Shi 
This work was supported by the Strategic Priority Research Program of CAS(XDB29010000);the National Science and Technology Major Project(2018ZX10101004 and 2018ZX10733403);the National Key Research and Development Program of China(2020YFC0845900,2016YFD0500300 and 2016YFE0205800);the National Natural Science Foundation of China(82041016,81871658,81673358 and 21807109);a grant from the Bill&Melinda Gates Foundation and and is partially supported by the Yanqi Lake Meeting organized by the Academic Divisions of CAS;Y.S.is supported by the Youth Innovation Promotion Association of CAS.
Dear Editor,The second wave of the coronavirus disease(COVID-19)pandemic has recently appeared in Europe.Most European countries,such as France,Germany,and Italy,have announced the implementation of a new round of epi...
关键词:PREVENTION DRUG DRUGS 
Phytochemical analysis of Berberis lyceum methanolic extract and its antiviral activity through the restoration of MAPK signaling pathway modulated by HCV NS5A被引量:1
《Asian Pacific Journal of Tropical Biomedicine》2021年第3期132-140,共9页Koloko Brice Landry Shafiq Azam Sidra Rehman Somayya Tariq Bushra Iqbal Mateen Abbas Dieudonné Massoma Lembè Bushra Ijaz 
supported by the CEMB-TWAS Postgraduate Fellowship(FR number 3240286682,2015)granted to Mr.Koloko Brice Landry
Objective:To evaluate the antiviral activity and phytochemicals of selected plant extracts and their effect on the mitogen-activated protein kinase(MAPK)signaling pathway modulated by hepatitis C virus(HCV)nonstructur...
关键词:ANTI-HCV HCV NS5A Berberis lyceum MAPK pathway PHYTOCHEMICALS HPLC 
Comparative study on anti-HCV testing using plasma, dried plasma spots (DPS), and dried blood spots (DBS)
《Biosafety and Health》2021年第1期50-55,共6页Jieqiong Ma Lin He Kai Chen Yuehua Wang Yanan Ren Wenge Xing Yan Jiang 
supported by the National Science and Technology Major Project of China in the 13th Five-Year(2017ZX10201101-002-003)
The aim of this study was to evaluate the performance of an assay using dried plasma spot(DPS)and dried blood spot(DBS)samples for the serological detection of anti-hepatitis C virus(HCV)antibodies.Between January and...
关键词:HCV PLASMA Dried plasma spots Dried blood spots Spearman's correlation coefficient 
两种不同全自动酶免检测系统检测性能比对研究
《江西医药》2019年第5期568-570,共3页彭小华 汤明 章丹 
目的比较两种不同全自动酶免检测系统检测性能。方法在同一工作环境下,使用相同的质控品作为标本,并用指定厂家试剂对其进行HBsAg、Anti-HCV试、Anti-HIV、Anti-TP检测,一组用Uranus-AE-100全自动酶免分析仪进行检测,另一组用Freedom Ev...
关键词:全自动酶免检测系统 性能对比 HBsAg ANTI-HCV ANTI-HIV ANTI-TP 
化学发光微粒子免疫分析法检测Anti-HCV结果的假阳性分析
《现代医学与健康研究电子杂志》2018年第20期20-21,共2页陈影 姚玮 王庆保 余金芸 
目的分析化学发光微粒子免疫分析法(CMIA)检测Anti-HCV阳性结果中假阳性的情况。方法选取本实验室测定Anti-HCV结果为阳性的标本67例,用RT-PCR方法检测血清中HCV-RNA的载量,判断标准:HCV-RNA(+)为真阳,HCV-RNA(—)为假阳。结果 67例经HC...
关键词:丙型肝炎 ANTI-HCV 化学发光法 
Synthesis and biological evaluation of 12-benzyl matrinic amide derivatives as a novel family of anti-HCV agents被引量:4
《Chinese Chemical Letters》2016年第7期1052-1057,共6页Sheng Tang Zong-Gen Peng Xin Zhang Xin-Yue Cheng Wen-Jing Li Jian-Dong Jiang Ying-Hong Li Dan-Qing Song 
supported by the National Natural Science Foundation of China (Nos. 21472246 and 81321004);the Beijing Natural Science Foundation (No. 7152097);National Mega-Project for Innovation Drugs (No. 2012ZX09103101-037)
A new series of 12-benzyl matrinic amide/ethanamide derivatives were synthesized from matrinine(1)and evaluated for their anti-HCV activity,taking compound 2 as the lead.SAR revealed that the introduction of a suita...
关键词:Matrinic acid Matrinic amide Hepatitis C virus Structure–activity relationship 
患者术前传染病患病率现状分析被引量:6
《中国卫生检验杂志》2016年第8期1198-1200,共3页王玲玲 贾海英 王昌敏 
目的分析28 427例患者术前各种感染性指标的现状,探讨其检查的必要性,进一步加强医院的生物安全防护,降低医护人员职业暴露风险,减少或避免医院内感染及医疗纠纷。方法对新疆某三甲医院2014年4月-2015年3月的住院患者进行术前传染病检查...
关键词:术前检测 HBSAG ANTI-HCV ANTI-HIV TP 
Direct anti-HCV agents被引量:6
《Acta Pharmaceutica Sinica B》2016年第1期26-31,共6页Xingquan Zhang 
Unlike human immunodeficiency virus(HIV)and hepatitis B virus(HBV),hepatitis C virus(HCV)infection is a curable disease.Current direct antiviral agent(DAA)targets are focused on HCV NS3/4A protein(protease),NS5 B prot...
关键词:Hepatitis C virus Cure HCV Sustained VIROLOGIC response DIRECT ANTIVIRAL AGENTS NS3/4A PROTEASE inhibitor 
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