ARG-GLY-ASP

作品数:26被引量:86H指数:5
导出分析报告
相关领域:医药卫生更多>>
相关作者:赵明彭师奇张琴姜文花张筱宜更多>>
相关机构:首都医科大学承德医学院吉林大学大连医科大学更多>>
相关期刊:《World Journal of Gastroenterology》《World Journal of Stem Cells》《吉林大学学报(理学版)》《肿瘤》更多>>
相关基金:国家自然科学基金教育部留学回国人员科研启动基金国家高技术研究发展计划辽宁省高校创新团队支持计划更多>>
-

检索结果分析

结果分析中...
条 记 录,以下是1-10
视图:
排序:
Integrin beta 3-overexpressing mesenchymal stromal cells display enhanced homing and can reduce atherosclerotic plaque
《World Journal of Stem Cells》2023年第9期931-946,共16页Hai-Juan Hu Xue-Ru Xiao Tong Li De-Min Liu Xue Geng Mei Han Wei Cui 
National Natural Science Foundation of China,No.82100301;Key Science and Technology Research Program of Hebei Provincial Department of Health,No,20221014.
BACKGROUND Umbilical cord(UC)mesenchymal stem cell(MSC)transplantation is a potential therapeutic intervention for atherosclerotic vascular disease.Integrin beta 3(ITGB3)promotes cell migration in several cell types.H...
关键词:ATHEROSCLEROSIS INFLAMMATION Integrin beta 3 Mesenchymal stem cells Arg-Gly-Asp structure Umbilical cord 
一种新的含有Arg-Gly-Asp三肽序列蛇毒解离素的分离纯化及生物活性研究被引量:3
《药学学报》2019年第5期897-905,共9页柯璐琳 陈艺云 赵宁宁 张琼 陈婉琼 邱秀梁 许云禄 
福建医科大学苗圃研究基金资助项目(2015MP030)
蛇毒是一种具有特殊药理活性的物质,其含有一系列能拮抗整合素的小分子多肽,称之为解离素。解离素可以阻断整合素依赖性血小板聚集、肿瘤生长和肿瘤转移等活性。从江浙短尾蝮蛇毒(Gloydius brevicaudus venom, GBV)中分离纯化出含有精...
关键词:短尾蝮蛇 精氨酸-甘氨酸-天门冬氨酸序列 解离素 分离纯化 生物学活性 
^18F-阿法肽的基础研发及临床转化历程被引量:2
《中华核医学与分子影像杂志》2019年第4期193-195,共3页陈小元 
一、^18F标记精氨酸-甘氨酸-天冬氨酸(Arg-Gly-Asp, RGD)显像剂的出现肿瘤血管新生是肿瘤发生、发展、侵袭、转移的标志性生物学行为,新生血管是肿瘤诊疗的有效靶点。整合素是组织微环境中调控细胞-细胞及细胞-胞外基质相互作用的核心分...
关键词:^18F 精氨酸-甘氨酸-天冬氨酸 ARG-GLY-ASP 整合素ΑVΒ3 肿瘤血管新生 肿瘤发生 转化 临床 
In Vitro Biocompatibility of MC3T3-E1 Osteoblast-like Cells on Arg-Gly-Asp Acid Peptides Immobilized Graphite-like Carbon Coating on Carbon/Carbon Composites
《Acta Metallurgica Sinica(English Letters)》2017年第6期558-566,共9页Sheng Cao He-Jun Li Ke-Zhi Li Jin-Hua Lu Lei-Lei Zhang 
supported by the National Natural Science Foundation of China under Grant Nos.51202194 and 51221001;the Programme of Introducing Talents of Discipline to Universities(‘‘111’’project of China)under Grant No.B08040
Carbon/carbon (C/C) composites were deposited with graphite-like carbon (GLC) coating, and then, Arg-Gly- Asp acid (RGD) peptides were successfully immobilized onto the functionalized GLC coating. GLC coating wa...
关键词:MC3T3-E1 osteoblast-like cells Carbon/carbon composites Graphite-like carbon (GLC) coating Arg-Gly-Asp acid (RGD) peptides Surface modification 
特异性细胞粘附Arg-Gly-Asp-Cys/三乙二醇单-11-巯基十一烷基醚界面的制备与电化学表征被引量:1
《化学通报》2015年第12期1133-1137,共5页单梅 胡家金 周珍 赵佳 周铁安 
国家自然科学基金项目(21275048);湖南省科技厅重点项目(2013TT1009);湖南省研究生科研创新项目(CX2015B262)资助
采用自组装技术将人工合成的细胞粘附分子精氨酸-甘氨酸-天冬氨酸-半胱氨酸(RGDC)和防止细胞非特异性粘附的三乙二醇单-11-巯基十一烷基醚(TGME)修饰于金电极表面,制备了致密的、稳定的、对细胞具有特异性粘附作用的传感界面。通过调整R...
关键词:细胞特异性粘附界面 精氨酸-甘氨酸-天冬氨酸-半胱氨酸 三乙二醇单-11-巯基十一烷基醚大鼠心肌细胞 Cr(Ⅵ)影响 
Effects of Integrins and Integrin αvβ3 Inhibitor on Angiogenesis in Cerebral Ischemic Stroke被引量:3
《Journal of Huazhong University of Science and Technology(Medical Sciences)》2014年第3期299-305,共7页毕佳佳 易黎 
Summary: Integrins such as αvβ3, α5β31 play a key role in angiogenesis regulation, invasion and metastasis, inflammation, wound healing, etc. The up-regulation of integrin αvβ3 after cerebral ischemic stroke ca...
关键词:integrin αvβ3 cerebral ischemic stroke vascular endothelial growth factor cyclo[Arg-Gly-Asp-D-Phe-Val] 
A Dual Ligand Targeted Nanoprobe with High MRI Sensitivity for Diagnosis of Breast Cancer被引量:4
《Chinese Journal of Polymer Science》2014年第3期321-332,共12页Fa-ming Gong Zuo-quan Zhang Xiao-dong Chen Lu Zhang Xing-su Yu Qi-hua Yang Xin-tao Shuai 梁碧玲 程度 
supported by the 863 Programs of China(No.2009AA03Z310);National Natural Science Foundation of China(Nos.21174166,30973419);the Ph.D.Programs Foundation of Ministry of Education of China(No.20100171110011);the Postdoctoral Foundation(No.201003370);Natural Science Foundation(Nos.9351027501000003,S2011020003140);S&T Programs of Guangdong Province(Nos.2010B031500011,2009B030803003,2009B030801107,2012B031800135);SYSU Projects for Promotion of Key and Emerging Interdisciplinary Researches(10ykjc18);Young Teachers(11lgpy44)
Antibody targeted delivery is an effective strategy to improve the diagnostic imaging outcome of nanoscale imaging agents in the focal areas. Dual targeting micelles encapsulating superparamagnetic iron oxide were pre...
关键词:Block copolymer micelle Superparamagnetic iron oxide (SPI0) Breast cancer Magnetic resonance imaging(MRI) HERCEPTIN c(Arg-Gly-Asp-d-Phe-Lys) (cRGDfK). 
Novel Chemical Strategy for the Synthesis of RGDCySS Tetrapeptide
《Chemical Research in Chinese Universities》2014年第1期103-107,共5页XU Baofeng YANG Sen ZHU Jinming MA Yudan ZHAO Gang GUO Yi XU Li 
Supported by the National Natural Science Foundation of China(No.81271697), the Science Foundation of Changchun City, China(No.09SF02), the China Postdoctoral Science Foundation(No.20100481048), the Specialized Research Fund for the Doctoral Program of Higher Education of China(No.20100061120077) and the Social Development Project of Science and Tech- nology Department of Jilin Province, China(Nos.20106031, 20120967, YYZX2012).
A new route was described to synthesize Arg-Gly-Asp-X(RGDX,X=amino acid) tetrapeptide.To better understand the method,the tetrapeptide Arg-Gly-Asp-CySS(RGDCySS) was chosen as a model target for X.First,GDCySS was ...
关键词:Arg-Gly-Asp(RGD) Arg-Gly-Asp-X(RGDX) Peptide synthesis Arg-Gly-Asp-CySS(RGDCySS) Chemical method N-Carboxy-a-amino acid anhydride(NCA) 
Antitumor effects of mutant endostatin are enhanced by Bcl-2 antisense oligonucleotides in UM-UC-3 bladder cancer cell line被引量:5
《Chinese Medical Journal》2013年第15期2834-2839,共6页REN Ming-hua YU Jing-song SONG Er-lin ZHANG Cheng MA Li JIAO Zhi-xing ZHAO Wei-ming SHAN Yu-juan NI Shao-bin 
Background Endostatin is a potent inhibitor of tumor angiogenesis. In the preliminary studies, we developed a mutant endostatin containing Arg-Gly-Asp-Arg-Gly-Asp (RGDRGD) sequences. In this study, we compared the a...
关键词:ENDOSTATIN BCL-2 antisense oligonucleotides ARG-GLY-ASP 
Specific targeting of angiogenesis in lung cancer with RGD-conjugated ultrasmall superparamagnetic iron oxide particles using a 4.7T magnetic resonance scanner被引量:6
《Chinese Medical Journal》2013年第12期2242-2247,共6页LIU Can LIU Dong-bo LONG Guo-xian WANG Jun-feng MEI Qi HU Guang-yuan QIU Hong HU Guo-qing 
Background Angiogenesis is an essential step for tumor development and metastasis.The cell adhesion molecule αvβ3 integrin plays an important role in angiogenesis and is a specific marker of tumor angiogenesis.A nov...
关键词:ultrasmall superparamagnetic iron oxide particles ARG-GLY-ASP avfβ magnetic resonance imaging 
检索报告 对象比较 聚类工具 使用帮助 返回顶部