Background:Apoptosis signal-regulating kinase 1(ASK1)is a MAP3K kinase in the MAPK signaling pathway activated by stressors and triggers downstream biological effects such as inflammation and apoptosis;therefore,inhib...
Fujian Provincial Health and Wellness Scientific Research Talent Development Program;grant number:2019-1-5
Objective:To investigate the effect of serum deprivation response-related protein(SDPR)on hepatocellular carcinoma(HCC)cells through the ASK1-JNK/p38 MAPK signaling pathway.Methods:A total of 30 HCC tissue samples and...
Financial support for this study was provided by the National Natural Science Foundation of China(grant nos.81870067 and 82170664).
Background: Hepatic ischemia-reperfusion injury (HIRI) stands as an unavoidable complication arising from liver surgery, profoundly intertwined with its prognosis. The role of lysine methyltransferase SET domain bifur...