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作品数:533被引量:1087H指数:13
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相关机构:中国科学院北京邮电大学南京航空航天大学中山大学更多>>
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  • 期刊=Chinese Journal of Traumatologyx
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Identification of overlay differentially expressed genes in both rats and goats with blast lung injury through comparative transcriptomics
《Chinese Journal of Traumatology》2024年第1期34-41,共8页Hong Wang Jun-Hong Gao Xiao-Lin Fan Qing Lu Liang Li Ning Ma Qi Wang Yu-Hao Zhang 
Natural Science Basis Research Plan in Shaanxi Province of China(Program No.2023-JC-YB-684).
Purpose:To identify the potential target genes of blast lung injury(BLI)for the diagnosis and treatment.Methods:This is an experimental study.The BLI models in rats and goats were established by conducting a fuel-air ...
关键词:Blast lung injury TRANSCRIPTOMIC Target genes Differentially expressed genes 
Effects of orientation and distance of goats on blast lung injury characteristics on a plateau above 4500-meter被引量:3
《Chinese Journal of Traumatology》2023年第3期139-146,共8页Zhao-Xia Duan Guan-Hua Li Jie-Yuan Zhang Meng-Sheng Deng Kui-Jun Chen Liang-Chao Zhang Xiang-Yun Cheng Jing Chen Guang-Ming Yang Jian-Min Wang 
Military Logistic(s)Scientific Research Program of China(ALJ18J001)。
Purpose:High explosives are used to produce blast waves to study their biological effects.The lungs are considered as the critical target organ in blast-effect studies.The degree of lung hemorrhaging is related to bot...
关键词:Blast injuries Lung injury PLATEAU 
Global gene expression profiling of blast lung injury of goats exposed to shock wave被引量:5
《Chinese Journal of Traumatology》2020年第5期249-257,共9页Hong Wang Wen-Juan Zhang Jun-Hong Gao Jin-Ren Liu Zhi-Yong Liu Bao-Qing Xia Xiao-Lin Fan Cun-Zhi Li Ai-Rong Qian 
This work was supported by Science and Technology Development Fund for Institute for Hygiene of Ordnance(KY202007).
Purpose:Blast lung injury(BLI)is the most common damage resulted from explosion-derived shock wave in military,terrorism and industrial accidents.However,the molecular mechanisms underlying BLI induced by shock wave a...
关键词:Blast lung injury Shock wave Differentially expressed genes RNA sequencing TRANSCRIPTOME 
Value of lung ultrasound score for evaluation of blast lung injury in goats被引量:11
《Chinese Journal of Traumatology》2020年第1期38-44,共7页Yu-Qi Xue Chun-Shuang Wu Hua-Cai Zhang Juan Du Jian-Hui Sun An-Qiang Zhang Ling Zeng Mao Zhang Jian-Xin Jiang 
supported by State Key Laboratory of Trauma,Burns and Combined Injury Project(No.SKLYQ201901,No.SKLKF201801).
Purpose:To establish a severe blast lung injury model of goats and investigate the feasibility of lung ultrasonic score in the evaluation of blast lung injury.Methods:Twenty female healthy goats were randomly divided ...
关键词:BLAST INJURIES LUNG INJURY Goats Bio-shock tube 
An open air research study of blast-induced traumatic brain injury to goats被引量:3
《Chinese Journal of Traumatology》2015年第5期267-274,共8页Hui-Jun Chen Chuan Xu Yue Li Zhi-Qiang Chen Guan-Hua Li Zhao-Xia Duan Xiao-Xia Li Jie-Yuan Zhang Zhe Wang Hua Feng Bing-Cang Li 
special funds for major state basic research project,China,grants from the National Natural Science Foundation of China,grant from the funds of the State Key Laboratory of Trauma,Burn and Combined Injury
Purpose: we once reported blast-induced traumatic brain injury (bTBI) in confined space. Here, bTBI was studied again on goats in the open air using 3.0 kg trinitrotoluene. Methods: The goats were placed at 2, 4, ...
关键词:Brain injuries Explosive blast Open-air field S-100 Neuron specific enolase 
Blast-induced traumatic brain injury: a new trend of blast injury research被引量:4
《Chinese Journal of Traumatology》2015年第4期201-203,共3页Yan Zhao Zheng-GuoWang 
Blast injury has become the major life- and function-threatening injuries in recent warfares. There is increased research interest in the mental disorders caused by blast-induced traumatic brain injury (bTBI), which...
关键词:Blast injuries Cognitive dysfunction Stress disorders Post-traumatic 
Chronic caffeine exposure attenuates blast-induced memory deficit in mice被引量:5
《Chinese Journal of Traumatology》2015年第4期204-211,共8页Ya-Lei Ning Nan Yang Xing Chen Zi-Ai Zhao Xiu-Zhu Zhang Xing-Yun Chen Ping Li Yan Zhao Yuan-Guo Zhou 
We gratefully acknowledge Prof. Zhi-Yong Yin, senior engineers Xiao-Yan Li and Xin Ning for their technical support on the BST-I bio-shock tube. We thank Academician Zheng-Guo Wang for critically reading and editing the manuscript. This work was supported by the grants from National Natural Science Foundation of China (No. 81201461), Key Project of Medicine and Health of PLA (No. 08G098) and the Natural Science Foundation of Chongqing, China (No.CSTC2012jjAI0107).
Objective: To investigate the effects of three different ways of chronic caffeine administration on blast- induced memory dysfunction and to explore the underlying mechanisms. Methods: Adult male C57BL/6 mice were u...
关键词:Brain injuries Caffeine Memory disorders Blast injuries 
Development of a new biomechanical indicator for primary blast-induced brain injury
《Chinese Journal of Traumatology》2015年第1期10-12,共3页Feng Zhu Cliff C. Chou King H. Yang Albert I. King 
Primary blast-induced traumatic brain injury (bTBI) has been observed at the boundary of brain tissue and cerebrospinal fluid (CSF). Such injury can hardly be explained by using the theory of compressive wave prop...
关键词:Traumatic brain injury Shock wave Shear wave Analytical model Numerical simulation 
Changes of serum Tau, GFAP, TNF-α and malonaldehyde after blast-related traumatic brain injury被引量:12
《Chinese Journal of Traumatology》2014年第6期317-322,共6页Liu Mengdong Luo Peng Wang Zhanjiang Fei Zhou 
The work was supported by National Natural Science Foundation of China (No. 30930093), National Science and Technology Major Project of China (2013ZX 09J13109-02C), National Science & Technology Pillar Program of China (No. 2012BAI11B02), Program for Changjiang Scholars and Innovative Research Team in University (No. IRT1053), and Research Foundation of PLA (No. 2010gxjs078 and No. AWS11J008).
Objective: To determine the changes of serum Tau protein, glial fibrillary acidic protein (GFAP), tumor necrosis factor alpha (TNF-α), and malonaldehyde (MDA) in rats after blast-related traumatic brain injury...
关键词:Blast-related traumatic brain injury Tau proteins Glial fibrillary acidic protein Tumor necrosis factor-alpha MALONDIALDEHYDE 
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