Natural Science Basis Research Plan in Shaanxi Province of China(Program No.2023-JC-YB-684).
Purpose:To identify the potential target genes of blast lung injury(BLI)for the diagnosis and treatment.Methods:This is an experimental study.The BLI models in rats and goats were established by conducting a fuel-air ...
Military Logistic(s)Scientific Research Program of China(ALJ18J001)。
Purpose:High explosives are used to produce blast waves to study their biological effects.The lungs are considered as the critical target organ in blast-effect studies.The degree of lung hemorrhaging is related to bot...
This work was supported by Science and Technology Development Fund for Institute for Hygiene of Ordnance(KY202007).
Purpose:Blast lung injury(BLI)is the most common damage resulted from explosion-derived shock wave in military,terrorism and industrial accidents.However,the molecular mechanisms underlying BLI induced by shock wave a...
supported by State Key Laboratory of Trauma,Burns and Combined Injury Project(No.SKLYQ201901,No.SKLKF201801).
Purpose:To establish a severe blast lung injury model of goats and investigate the feasibility of lung ultrasonic score in the evaluation of blast lung injury.Methods:Twenty female healthy goats were randomly divided ...
special funds for major state basic research project,China,grants from the National Natural Science Foundation of China,grant from the funds of the State Key Laboratory of Trauma,Burn and Combined Injury
Purpose: we once reported blast-induced traumatic brain injury (bTBI) in confined space. Here, bTBI was studied again on goats in the open air using 3.0 kg trinitrotoluene. Methods: The goats were placed at 2, 4, ...
Blast injury has become the major life- and function-threatening injuries in recent warfares. There is increased research interest in the mental disorders caused by blast-induced traumatic brain injury (bTBI), which...
We gratefully acknowledge Prof. Zhi-Yong Yin, senior engineers Xiao-Yan Li and Xin Ning for their technical support on the BST-I bio-shock tube. We thank Academician Zheng-Guo Wang for critically reading and editing the manuscript. This work was supported by the grants from National Natural Science Foundation of China (No. 81201461), Key Project of Medicine and Health of PLA (No. 08G098) and the Natural Science Foundation of Chongqing, China (No.CSTC2012jjAI0107).
Objective: To investigate the effects of three different ways of chronic caffeine administration on blast- induced memory dysfunction and to explore the underlying mechanisms. Methods: Adult male C57BL/6 mice were u...
Primary blast-induced traumatic brain injury (bTBI) has been observed at the boundary of brain tissue and cerebrospinal fluid (CSF). Such injury can hardly be explained by using the theory of compressive wave prop...
The work was supported by National Natural Science Foundation of China (No. 30930093), National Science and Technology Major Project of China (2013ZX 09J13109-02C), National Science & Technology Pillar Program of China (No. 2012BAI11B02), Program for Changjiang Scholars and Innovative Research Team in University (No. IRT1053), and Research Foundation of PLA (No. 2010gxjs078 and No. AWS11J008).
Objective: To determine the changes of serum Tau protein, glial fibrillary acidic protein (GFAP), tumor necrosis factor alpha (TNF-α), and malonaldehyde (MDA) in rats after blast-related traumatic brain injury...