supported by the Lingang Laboratory,Grant No.LG-GG-202204-01;the National Natural Science Foundation(82121005,32130022);CAS Strategic Priority Research Program(XDB37030103);Shanghai Municipal Science and Technology Major Project(2019SHZDZX02).
Therapeutic antibodies are at the forefront of biotherapeutics,valued for their high target specificity and binding affinity.Despite their potential,optimizing antibodies for superior efficacy presents significant cha...