supported by the National Key Research and Development Program of China(No.2022YFC2304501 and No.2021YFC2301800);the Fundamental Research Funds for the Central Universities(2023QZJH50);the Medical Health Science and Technology Project of the Zhejiang Provincial Health Commission(No.2022RC141);the Chinese National Natural Science Foundation(No.81870425).
Citation of this article:Zhou R,Chen J,Huang R,Yang Y,Shi Y.The Failure Rate of Liver Stiffness Measured by Vibrationcontrolled Transient Elastography in the United States and Relevant Factors.J Clin Transl Hepatol 20...
funded by Roche Diagnostics GmbH and partly supported by the“Center of Excellence for Metabolic Associated Fatty Liver Disease,National Sun Yat-sen University,Kaohsiung”,under The Featured Areas Research Center Program within the framework of the Higher Education Sprout Project by the Ministry of Education in Taiwan.
Background and Aims:Early detection of hepatocellular carcinoma(HCC)is crucial for improving survival in patients with chronic hepatitis.The GALAD algorithm combines gen-der(biological sex),age,α-fetoprotein(AFP),Len...
Cirrhosis is often characterized by decreased liver function,ranging from a compensated,typically asymptomatic phase to a decompensated phase characterized by the appearance of ascites or variceal bleeding,and ultimat...
supported by the Biocodex Microbiota Foundation(National Research Grant Russia 2019).The sponsor did not participate in the development of the study design,influence the conduct of the study,data analysis,or the decision to publish.
Background and Aims:Gut dysbiosis and abnormal cytokine profiles are common in cirrhosis.This study aimed to evaluate the correlations between them.Methods:In the blood plasma of cirrhosis patients and controls,27 cyt...
supported by the Jiangsu Province Capability Improvement Project through Science,Technology and Education(grant number:ZDXK202248,recipient:QZ);National Natural Science Foundation of China(grant number:82373654,recipient:CS);Science and Technology Young Scientific and Technological Talents Project of Jiangsu Province(grant number:2021-50,recipient:CS);Key project of Changzhou Medical Center,Nanjing Medical University(grant number:CZKYCMCM202210,recipient:CS);Chinese Academy of Medical Sciences(grant number:2019RU038,recipient:CS).
Background and Aims:Age-related mosaic chromosomal alterations(mCAs)detected from genotyping of blood-de-rived DNA are structural somatic variants that indicate clonal hematopoiesis.This study aimed to investigate whe...
supported by the Shanghai Key Specialty of Traditional Chinese Clinical Medicine(grant number shslczdzk01201);the National Science and Technology Major Project(grant number 2018ZX10302204);Shanghai University of Traditional Chinese Medicine(grant number ZYJK FW201811013).
Background and Aims:The application of antifibrotic drugs to treat patients with chronic liver diseases who are receiving antiviral therapies for hepatocellular carcinoma(HCC)has not been established.Here,we aimed to ...
Hepatocellular carcinoma(HCC)is the most common primary tumor of the liver and often evolves from regenerating nodules in liver cirrhosis.While there have been significant advances in the treatment of HCC,the overall ...
supported by The National Natural Scientific Foundation of China(Grant No.81972230).
Hepatic myelopathy(HM)is a rare neurological complication in the end stage of many liver diseases and is characterized by bilateral spastic paraparesis without sensory and sphinc-ter dysfunction.It occurs owing to met...
supported by the National Natural Science Foundation of China(NSFC)(82300660 XW,81870406 HR and 81602939 HL);Beijing Natural Science Foundation(7232195 XW);Peking University Medicine Sailing Program for Young Scholars’Scientific&Technological Innovation(BMU2023YFJHPY025);Capital’s Funds for Health Improvement and Research(2020-4-4087 HL);Peking University People’s Hospital Scientific Research Development Funds(RDJP2022-60 XW)and Qi-Min Project.
Background and Aims:China accounts for 14.9%of total cirrhosis deaths worldwide.A detailed and comprehensive understanding of the contemporary status of cirrhosis mortality in China is crucial for establishing strateg...
Sarcopenia is a well-known complication of chronic liver disease(CLD),and it is almost always observed in patients with cirrhosis,at least in those with decompensated disease.Since nonalcoholic fatty liver disease(NAF...