supported by the National Natural Science Foundation of China(32325049,U22A20529,32303000);Zhejiang Provincial Natural Science Foundation(LQ24C190009);Ningbo Natural Science Foundation(2022J192);Zhejiang Provincial Top Key Discipline of Biological Engineering(1741000592)。
In reptiles,such as the red-eared slider turtle(Trachemys scripta elegans),gonadal sex determination is highly dependent on the environmental temperature during embryonic stages.This complex process,which leads to dif...
supported by the National Natural Science Foundation of China(32025037);Ministry of Science and Technology of China(2023YFD2401603);Ministry of Agriculture and Rural Affairs of China(NK2022010207);Science and Technology Special Fund of Hainan Province(ZDYF2024XDNY256);Natural Science Foundation of Wuhan。
Zebrafish serve as a valuable model organism for studying germ cell biology and reproductive processes.The AB strain of zebrafish is proposed to exhibit a polygenic sex determination system,where most males initially ...
supported by the National Natural Science Foundation of China(32072806,31572399);National Key Research and Development Program of China(2022YFD1302201);Program of Shaanxi Province Science and Technology Innovation Team(2019TD-036);Major Projects of Natural Science Foundation of Inner Mongolia Autonomous Region(2020ZD10);Key Research and Development Program of Shaanxi Province(2022NY-044);Key Technologies Demonstration of Animal Husbandry in Shaanxi Province(20221086)。
Bacterial or viral infections,such as Brucella,mumps virus,herpes simplex virus,and Zika virus,destroy immune homeostasis of the testes,leading to spermatogenesis disorder and infertility.Of note,recent research shows...
This work was supported by the China National Basic Research Program(2016YFA0100203);National Natural Science Foundation of China(31572399Detail,32072806,32072815,32002246);State Key Lab of Reproductive Regulation&Breeding of Grassland Livestock(SKL-OT-201801);Science and Technology Major Project of Inner Mongolia Autonomous Region of China(ZDZX2018065);and Shaanxi Province Science and Technology Innovation Team(2019TD-036);The authors thank Dr.John Clotaire Daguia Zambe for helpful comments about this paper,Jia Fang for the PGL3-NF-κB luciferase reporter plasmid,and Dong-Xue Che for bioinformatics analysis.
Double sex and mab-3-related transcription factor 1(Dmrt1),which is expressed in goat male germline stem cells(mGSCs)and Sertoli cells,is one of the most conserved transcription factors involved in sex determination.I...
Special Preliminary Study of 973(2008CB117015);Changjiang Scholars and Innovative Research Team Projects(IRT0734);Priority Themes of Major Science and Technology in Zhejiang Province(2009C12077);the K.C.Wong Magna Fund of Ningbo University
The Dmrt family of genes are involved in sex differentiation in different species of invertebrates, and some vertebrates including human. In this study, we cloned the full-length eDNA of ayu (Plecoglossus altivelis)...