Supported by the Key R&D Projects of Hainan Province,No.ZDYF2022SHFZ295.
BACKGROUND Schizophrenia(SZ),a chronic and widespread brain disorder,presents with complex etiology and pathogenesis that remain inadequately understood.Despite the absence of a universally recognized endophenotype,pe...
supported by the National Key R&D Program of China(2023YFC3404200 to Y.Z.);the National Natural Science Foundation of China(T2188102 and 21991134 to C.F.,22325406 to J.L.,and 12305400 to Q.Y.);the New Cornerstone Investi-gator Program(to C.F.),the 2022 Shanghai‘Science and Tech-nology Innovation Action Plan’Fundamental Research Project(22JC1401203 to Y.Z.);the Xiangfu Lab Research Project(XF012022E0100 to C.F.).
Abnormal levels of zinc ions within endo-lysosomes have been implicated in the progression of Alzheimer’s disease(AD),yet the detection of low-concentration zinc ions at the organelle level remains challenging.Here w...