云南高校图书馆联盟文献共享服务平台- DOMAIN

DOMAIN: 作品数：1354被引量：1998H指数：15; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：寇辉饶三平梁基华赵彬徐罗山更多>>; 相关机构：四川大学陕西师范大学中国科学院湖南大学更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划国家高技术研究发展计划中国博士后科学基金更多>>

Recognition of H3K9me1 by maize RNA-directed DNA methylation factor SHH2被引量：2: 《Journal of Integrative Plant Biology》2021年第6期1091-1096,共6页Yuhua Wang Xuelin Zhou Jinyan Luo Suhui Lv Rui Liu Xuan Du Bei Jia Fengtong Yuan Heng Zhang Jiamu Du; supported by National Natural Science Foundation of China(31770782);the Ministry of Science and Technology of China(2016YFA0503200);the Shenzhen Science and Technology Program(JCYJ20200109110403829 and KQTD20190929173906742);Key Laboratory of Molecular Design for Plant Cell Factory of Guangdong Higher Education Institutes(2019KSYS006)to J.D.; RNA-directed DNA methylation(Rd DM) is a plant-specific de novo DNA methylation pathway,which has extensive cross-talk with histone modifications. Here, we report that the maize RdDM regulator SAWADEE HOMEODOMAIN HOMO...; 关键词：EPIGENETICS H3K9me1 MAIZE RNA-directed DNA methylation SAWADEE domain SHH2

Crystal structure of SARS-CoV-2 nucleocapsid protein RNA binding domain reveals potential unique drug targeting sites被引量：25: 《Acta Pharmaceutica Sinica B》2020年第7期1228-1238,共11页Sisi Kang Mei Yang Zhongsi Hong Liping Zhang Zhaoxia Huang Xiaoxue Chen Suhua He Ziliang Zhou Zhechong Zhou Qiuyue Chen Yan Yan Changsheng Zhang Hong Shan Shoudeng Chen; supported by National Natural Science Foundation of China(31770801);Special Fund for Scientific and Technological Innovation Strategy of Guangdong Province of China(2018B030306029 and 2017A030313145);National Natural Science Foundation of China(81430041,81620108017);National Key Basic Research Program,China(SQ2018YFC090075);National Natural Science Foundation of China(81870019); The outbreak of coronavirus disease(COVID-19)caused by SARS-CoV-2 virus continually lead to worldwide human infections and deaths.Currently,there is no specific viral protein-targeted therapeutics.Viral nucleocapsid p...; 关键词：COVID-19 CORONAVIRUS SARS-CoV-2 Nucleocapsid protein RNA binding domain Crystal structure Antiviral targeting site

Cryo-EM structures of inactive and active GABAB receptor被引量：6: 《Cell Research》2020年第7期564-573,共10页Chunyou Mao Cangsong Shen Chuntao Li Dan-Dan Shen Chanjuan Xu Shenglan Zhang Rui Zhou Qingya Shen Li-Nan Chen Jianfeng Liu Yan Zhang; We are grateful to H.Eric Xu for generously providing the plasmids of the heterotrimeric G protein.We thank S.Chang for technical support in cryo-EM data collection at the Center of Cryo-Electron Microscopy,Zhejiang University;Protein expression and purification were performed at the Protein Facilities,Zhejiang University School of Medicine with the support of C.Ma.J.L.was supported by the Ministry of Science and Technology(2018YFA0507003);the National Natural Science Foundation of China(81720108031,81872945,31721002 and 31420103909);the Program for Introducing Talents of Discipline to the Universities of the Ministry of Education(B08029);the Mérieux Research Grants Program of the Institut Mérieux.Y.Z.was supported by the National Natural Science Foundation of China(81922071);the National Key Basic Research Program of China(2019YFA0508800);Zhejiang Province Natural Science Fund for Excellent Young Scholars(LR19H310001);the Fundamental Research Funds for the Central Universities(2019XZZX001-01-06).; Metabotropic GABAB G protein-coupled receptor functions as a mandatory heterodimer of GB1 and GB2 subunits and mediates inhibitory neurotransmission in the central nervous system.Each subunit is composed of the extrac...; 关键词：domain. inactive RATIONAL

A modified domain reduction method for numerical simulation of wave propagation in localized regions被引量：6: 《Earthquake Engineering and Engineering Vibration》2019年第1期35-52,共18页Luo Chao Lou Menglin Gui Guoqing Wang Hao; National Natural Science Foundation of China under Grant Nos.91315301,51478279;the State Key Laboratory Basic Theory Foundation of the Ministry of Science and Technology of China under the Grant SLDRCE08-A-07; A modified domain reduction method(MDRM) that introduces damping terms to the original DRM is presented in this paper. To verify the proposed MDRM and compare the computational accuracy of these two methods, a numeric...; 关键词：MODIFIED DOMAIN REDUCTION METHOD DOMAIN REDUCTION METHOD VISCOUS BOUNDARY VISCOUS spring BOUNDARY transmitting BOUNDARY wave propagation

Nanosecond Characterization of Regional Domain Imprint from Fast Domain Switching Currents in Pb(Zr,Ti)O_3 Thin Films: 《Chinese Physics Letters》2016年第2期122-124,共3页江钧江安全; Supported by the National Key Basic Research Program of China under Grant No 2014CB921004;the National Natural Science Foundation of China under Grant Nos 61225020 and 61176121;the Program for Professor of Special Appointment(Eastern Scholar)in Shanghai; The traditional imprint characterization of ferroelectric thin films estimates imprint time dependence of the mean coercive voltage of all domains from a polarization-voltage hysteresis loop, which shows a semilogarit...; 关键词：of from in TI

Mesh Deformation Method Based on Mean Value Coordinates Interpolation被引量：1: 《Acta Mechanica Solida Sinica》2016年第1期1-12,共12页Shuli Sun Shuming Lv Yuan Yuan Mingwu Yuan; Project supported by the National Basic Research Program of China(No.2010CB731503);the National Natural Science Foundation of China(Nos.11172004 and 10772004);the Beijing Municipal Natural Science Foundation(No.1102020); Mesh deformation technique is widely used in many application fields, and has re- ceived a lot of attentions in recent years. This paper focuses on the methodology and algorithm of algebraic type mesh deformation for ...; 关键词：unstructured mesh mesh deformation mean value coordinates （MVC） visibilityanalysis domain partition

Recent Developments in Computing Streamfunction and Velocity Potential in a Limited Domain被引量：1: 《Atmospheric and Oceanic Science Letters》2015年第6期403-408,共6页CAO Jie XU Qin GAO Shou-Ting; supported by the National Basic Research Program of China(Grant No.2012CB417201);the National Science and Technology Support Program(Grant No.GYHY201406001);the National Natural Science Foundation of China(Grant No.41205033);the Key Project of the Key Laboratory of Atmosphere and Environments on the Plateau in Sichuan Province(Grant No.PAEKL-2014-C1); After first reviewing historical and current difficulties in solving streamfunction and velocity potential in a limited domain,and describing recent developments in obtaining accurate solutions in a limited domain wit...; 关键词：streamfunction VELOCITY potential LIMITED DOMAIN m

Molecular dissection of phage lysin PlySs2: integrity of the catalytic and cell wall binding domains is essential for its broad lytic activity: 《Virologica Sinica》2015年第1期45-51,共7页Yanling Huang Hang Yang Junping Yu Hongping Wei; supported by the National Natural Science Foundation of China (No. 31400126);Basic Research Program of the Ministry of Science and Technology of China (No. 2012CB721102);Chinese Academy of Sciences (No. KJZD-EW-L02);Open Research Fund Program of the State Key Laboratory of Virology of China (No. 2014IOV002);Key Laboratory of Emerging Infectious Diseases and Biosafety, Wuhan; The novel phage lysin PlySs2, is reported to be highly active against various bacteria, including staphylococci, streptococci and Listeria. However, the molecular mechanisms underlying its broad lytic spectrum remain ...; 关键词：STREPTOCOCCI LYSIN cell wall binding DOMAIN CATALYTIC DOMAIN bacterial resistance

Crystal structure of the YTH domain of YTHDF2 reveals mechanism for recognition of N6-methyladenosine被引量：39: 《Cell Research》2014年第12期1493-1496,共4页Tingting Zhu Ian A Roundtree Ping Wang Xiao Wang Li Wang Chang Sun Yuan Tian Jie Li Chuan He Yanhui Xu; We thank staff members ofbeamline BL17U at SSRF （Shanghai Synchrotron Radiation Facility, China） for their assistance in data collection, and Mr Lei Zhang and staff members of Biomedical Core Facility in Fudan University for their help on biochemical analyses. We thank Dr Jinbiao Ma for the help on synthesis of m6A-RNA. This work was supported by grants from the National Basic Research Program of China （2011CB965300）, the National Science ＆ Technology Major Project ＂Key New Drug Creation and Manufacturing Program＂ of China （2014ZX09507-002）, the National Natural Science Foundation of China （U1432242, 91419301, 31270779 and 31030019）, the Basic Research Project of Shanghai Science and Technology Commission （12JC 1402700）, and the ＂Shu Guang＂ project （11SG06） supported by Shanghai Municipal Education Commission and Shanghai Education Development Foundation.; Dear Editor, N6-methyladenosine （m6A） has been demonstrated to be ubiquitous in several types of eukaryotic RNAs, including messenger RNA （mRNA）, transfer RNA （tRNA）, ribosomal RNA （rRNA）, long non-coding RNA...; 关键词：晶体结构 mRNA 识别机制核糖体RNA 非编码RNA 信使RNA 转移RNA

Self-adaptive spatial image denoising model based on scale correlation and SURE-LET in the nonsubsampled contourlet transform domain被引量：5: 《Science China(Information Sciences)》2014年第9期68-82,共15页LIANG MeiYu DU JunPing LIU HongGang; supported by National Basic Research Program of China(973)(Grant No.2012CB821206);National Natural Science Foundation of China(Grant No.61320106006); A novel self-adaptive image denoising model based on scale correlation and Stein＇s unbiased risk estimate-linear expansion of thresholds（SURE-LET） in the nonsubsampled contourlet transform domain is proposed in thi...; 关键词：spatial images image denoising nonsubsampled contourlet transform SURE-LET scale correlation

高级检索 检索式检索

时间限定

期刊范围

学科限定全选

高级检索 检索式检索

时间限定

期刊范围

学科限定全选

DOMAIN

检索结果分析

下载全文

高级检索检索式检索

时间限定

期刊范围

学科限定全选

高级检索 检索式检索

时间限定

期刊范围

学科限定全选

DOMAIN

检索结果分析

下载全文

用户登录

高级检索检索式检索