supported by the National Key Research and Development Program of China(2022YFC2601800);the Key-Area Research and Development Program of Guangdong Province(2023B1111020007);the National Natural Science Foundation of China(32161143017,82173833,81973343,and 82272658);the Guangdong Basic and Applied Basic Research Foundation(2023B1515040006);the Open Program of Shenzhen Bay Laboratory(SZBL202009051006);the Guangdong Provincial Key Laboratory of Construction Foundation(2023B1212060022);the Sichuan Science and Technology Program(2022JDRC0042 and 2022NSFSC0776);the Joint Research Foundation of Chengdu Medical College and the Seventh People’s Hospital(2022LHTD-02,2021LHJYPJ-08,and 2022488);the Shenzhen Bay Scholars Program。
The ribosome is a cellular system responsible for translating the nucleotide code of mRNA into proteins.In human cells,this complex consists of four distinct ribosomal RNAs(rRNAs):The 28S,18S,5.8S,and 5S rRNAs,along w...