ENDOMORPHIN-1

作品数:5被引量:4H指数:2
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相关领域:医药卫生生物学更多>>
相关作者:李正红高琴王锐杨顶建单立冬更多>>
相关机构:蚌埠医学院安徽医科大学昭和大学陕西中医药大学更多>>
相关期刊:《Acta Pharmacologica Sinica》《Chinese Medical Journal》《International Journal of Organic Chemistry》《Journal of Chinese Pharmaceutical Sciences》更多>>
相关基金:国家自然科学基金更多>>
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Synthesis and Plasma Stability of Disulfide-Bridged Cyclic Endomorphin-1 Derivatives
《International Journal of Organic Chemistry》2012年第1期1-6,共6页Friederike M. Mansfeld Istvan Toth 
Endomorphin-1 is an endogenous opioid peptide that mediates pain relief through interaction with the μ-opioid receptor in the central nervous system. To enhance the metabolic stability of this tetrapeptide, cyclisati...
关键词:ENDOMORPHIN-1 OPIOID PEPTIDE CYCLISATION DISULFIDE 
Short reaction of C-peptide, glucagon-like peptide-1, ghrelin and endomorphin-1 for different style diet in type 2 diabetic patients被引量:2
《Chinese Medical Journal》2011年第21期3485-3489,共5页CHEN Yi WANG Xin ZHANG Mei-fang LI Yan-xiang LI Ying GU Ting XIA Fang-zhen YU Jiao LU Ying-li 
This work was supported by a grant from the National Natural Science Foundation of China (No. 81070677). Conflict of interest: None.
Background Food composition and style is changing dramatically now, which causes inappropriate secretion of hormones from brain, gastrointestinal and endo-pancreas, may be related to unbalance of glucose in blood. The...
关键词:C-PEPTIDE gut hormone ENDOMORPHIN-1 different style meal diabetes 
The Stability of Endomorphin-1 Solution
《Journal of Chinese Pharmaceutical Sciences》2003年第3期131-134,共4页刘晖 杨顶建 倪京满 王锐 
Aim To study the most stable pH value of endomorphin-1 solution and toestimate the shelf-life of EM-1 solution. Methods The content of EM-1 in its solution was determinedby HPLC, and stability was studied by accelerat...
关键词:ENDOMORPHIN-1 most stable pH value accelerated tests HPLC 
Endomorphin-1对佐剂性关节炎作用的研究被引量:2
《中国基层医药》2002年第9期804-805,共2页李正红 高琴 
目的 观察内吗啡肽 1 (endomorphin 1 ,EM 1 )对佐剂性关节炎动物的镇痛作用。 方法 制备大鼠佐剂性关节炎动物模型 ,采用钾离子透入法和辐射热 缩腿法两种测痛方法 ,观察腹腔注射EM 1 (50 μg/kg)的作用。 结果 EM 1对佐剂性关节...
关键词:ENDOMORPHIN-1 佐剂性关节炎 内吗啡肽-1 
Analgesic effect of endomorphin-1
《Acta Pharmacologica Sinica》2001年第11期976-980,共5页李正红 单立冬 蒋星红 郭试瑜 俞光第 久光正 印其章 
AIM: To study the analgesic effect of endomorphin-1 ( EM-1). METHODS: The experiment was performed in rats and mice to study the analgesic effect of intraperi-(oneal ( ip) injection of EM-1 with tail stimulation-vocal...
关键词:ENDOMORPHINS ANALGESIA mu opioid receptors drug tolerance NALOXONE cyprodime 
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