NALOXONE

作品数:102被引量:136H指数:7
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相关领域:医药卫生更多>>
相关作者:何国伟路景涛王斌杨沁周爱武更多>>
相关机构:苏州大学安徽医科大学香港中文大学上海医科大学更多>>
相关期刊:《Chinese Medical Journal》《外科研究与新技术(中英文)》《中华物理医学与康复杂志》《外文科技期刊数据库(文摘版)医药卫生》更多>>
相关基金:国家自然科学基金国家重点基础研究发展计划更多>>
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PBPK-PD model for predicting morphine pharmacokinetics,CNS effects and naloxone antagonism in humans
《Acta Pharmacologica Sinica》2024年第8期1752-1764,共13页Rui-jing Mu Tian-lei Liu Xiao-dong Liu Li Liu 
supported by the National Key Research and Development Program of China(Grant No.2022YFC3300902).
Morphine and morphine-6-glucuronide(M6G)produce central nervous system(CNS)effects by activating mu-opioid receptors,while naloxone is used mainly for the reversal of opioid overdose,specifically for the fatal complic...
关键词:MORPHINE NALOXONE PBPK-PD model MIOSIS respiratory depression ANALGESIA 
Exploring the Contribution of Pharmacists in Addressing the Opioid Crisis through Naloxone Prescriptions and Pharmacist-Led Interventions
《Pharmacology & Pharmacy》2024年第2期27-38,共12页Michelle Krey Sophia Villa Nadia Gharibyar Haroon Mesdaq 
The opioid epidemic in the United States continues to take the lives of many individuals, with overdoses continuing to rise every year. Naloxone is an opioid antagonist that is efficacious in temporarily reversing opi...
关键词:NALOXONE Narcan Opioid Crisis Opioid Epidemic PHARMACY PHARMACIST Interventions 
Acute opioid-induced gastroparesis successfully treated with naloxone: a case report
《Emergency and Critical Care Medicine》2023年第2期78-80,共3页Hao Rui Seet Joe-Anthony Rotella 
A 56-year-old man presented to the emergency department after an intentional overdose of oxycodone and ethanol.He was previously opioid-naive with no other medical history.He subsequently developed acute abdominal pai...
关键词:Case report GASTROPARESIS NALOXONE OPIOIDS 
Observation of the Clinical Effect of Combining Naloxone and Nimodipine in Patients with Severe Cerebral Infarction
《外文科技期刊数据库(文摘版)医药卫生》2022年第10期166-170,共5页HANZhaoqiang 
Objective: to observe the clinical effect of combining naloxone and nimodipine in patients with severe cerebral infarction. Methods: 68 patients with severe cerebral infarction admitted from January 2019 to December 2...
关键词:severe cerebral infarction NALOXONE NIMODIPINE neurological function adverse reactions 
Montanide ISA-720 and Naloxone in HBsAg Vaccine Formulation:Cytokine Profiling and Monitoring of Long-Lasting Humoral Immune Responses
《Biomedical and Environmental Sciences》2022年第9期792-803,共12页Mina Mirzaee Setareh Haghighat Bahareh Golkaran Fatemeh Asgarhalvaei Rayhaneh Mirzaee Morteza Taghizadeh Mohammad Ali Savoji Behzad Esfandiari Mehdi Mahdavi 
supported by a grant from the Deputy of Research and Technology,Health Ministry of Iran[Grant no.642];partially by a grant from the Pasteur Institute of Iran。
Objective This study aimed to investigate the effects of Montanide ISA-720 and Naloxone(NLX)in Hepatitis B surface antigen(HBsAg)vaccine formulation on cytokine and long-lasting antibody responses.Methods First,the HB...
关键词:HBSAG VACCINE NALOXONE Montanide ISA-720 Long-lasting humoral response 
Effects of Different Extinction for Morphine-CPP on Hippocampal EEG Power Spectrum in Mice
《Wuhan University Journal of Natural Sciences》2022年第3期265-272,共8页LI Chunchun GAO Jingyao WANG Xiaoqin WANG Gongwu CAO Jun 
the National Natural Science Foundation of China(31760278);NHC Key Laboratory of Drug Addiction Medicine of Kunming Medical University(2020DAMOP-002)。
The relationship between hippocampal electroencephalogram(EEG)power spectrum and the extinction of addiction memory was investigated.Forty KM mice(Kunming mice)that had successfully established morphine(MOR)-condition...
关键词:MORPHINE NALOXONE conditioned place preference hippocampus electroencephalogram(EEG)power spectrum 
Acupuncture plus naloxone hydrochloride in the treatment of coma after surgery for cerebral hemorrhage: a randomized controlled trial被引量:4
《Journal of Acupuncture and Tuina Science》2022年第2期134-138,共5页CHEN Min WU Shuangshuang TANG Peiying 
Objective To observe the efficacy of acupuncture combined with naloxone hydrochloride in the treatment of coma after surgery for cerebral hemorrhage and to explore its possible mechanism of action.Methods Seventy-two ...
关键词:Acupuncture Therapy Acupuncture Medication Combined NALOXONE Cerebral Hemorrhage Brain Edema COMA Randomized Controlled Trial 
Sodium alginate and naloxone loaded macrophage-derived nanovesicles for the treatment of spinal cord injury被引量:3
《Asian Journal of Pharmaceutical Sciences》2022年第1期87-101,共15页Xiaoyao Liu Xue Jiang Qi Yua Wenwen Shen He Tian Xifan Mei Chao Wu 
the financial support received from the Natural Science Foundation of Liaoning Province [No. 20180550155, 2021-MS-332];the National Natural Science Foundation of China (No.81671907, 81871556, 82072165);LiaoNing Revitalization Talents Program (No. XLYC1902108);Scientific Research Project of the Educational Department of Liaoning Province(No. JYTQN201917, JYTQN201919);Liaoning Provincial Key Laboratory of Marine Bioactive Substances and Technological Innovation Center of Liaoning Pharmaceutical Action and Quality Evaluation (No. 2020–10)。
Spinal cord injury(SCI)causes Ca^(2+) overload,which can lead to inflammation and neuronal apoptosis.In this study,we prepared a nanovesicle derived from macrophage membrane(MVs),which encapsulated sodium alginate(SA)...
关键词:NALOXONE Sodium alginate Spinal cord injury Macrophage membrane INFLAMMATION NEUROPROTECTION 
Discussion on Clinical Treatment Strategy and Effect of Acute Cerebrovascular Disease Complicated with Disturbance of Consciousness
《外文科技期刊数据库(文摘版)医药卫生》2021年第10期1091-1095,共8页WU Qi 
Objective: the purpose of this project is to explore the strategies and effects of clinical treatment for patients suffering from acute cerebrovascular diseases accompanied by conscious disturbance. Methods: 30 patien...
关键词:acute cerebrovascular disease disturbance of consciousness therapeutic strategy NALOXONE EFFECT 
Central spexin produces antinociceptive effect against inflammatory pain via Fos in mice
《解剖学杂志》2021年第S01期78-78,共1页Lyu Shuangyu Cui Binbin Zhang Xiaomei Zhou Yuchen 
Spexin/NPQ is a novel highly conserved neuropeptide.It has a widespread expression in the periphery and central nervous system.This study explored the mechanisms and effects of supraspinal spexin on in A ammatory pain...
关键词:PAIN NALOXONE ANTAGONIST 
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